BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

252 related articles for article (PubMed ID: 30121007)

  • 1. A Role for De Novo Purine Metabolic Enzyme PAICS in Bladder Cancer Progression.
    Chakravarthi BVSK; Rodriguez Pena MDC; Agarwal S; Chandrashekar DS; Hodigere Balasubramanya SA; Jabboure FJ; Matoso A; Bivalacqua TJ; Rezaei K; Chaux A; Grizzle WE; Sonpavde G; Gordetsky J; Netto GJ; Varambally S
    Neoplasia; 2018 Sep; 20(9):894-904. PubMed ID: 30121007
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Expression and Role of PAICS, a De Novo Purine Biosynthetic Gene in Prostate Cancer.
    Chakravarthi BV; Goswami MT; Pathi SS; Dodson M; Chandrashekar DS; Agarwal S; Nepal S; Hodigere Balasubramanya SA; Siddiqui J; Lonigro RJ; Chinnaiyan AM; Kunju LP; Palanisamy N; Varambally S
    Prostate; 2017 Jan; 77(1):10-21. PubMed ID: 27550065
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Role and regulation of coordinately expressed de novo purine biosynthetic enzymes PPAT and PAICS in lung cancer.
    Goswami MT; Chen G; Chakravarthi BV; Pathi SS; Anand SK; Carskadon SL; Giordano TJ; Chinnaiyan AM; Thomas DG; Palanisamy N; Beer DG; Varambally S
    Oncotarget; 2015 Sep; 6(27):23445-61. PubMed ID: 26140362
    [TBL] [Abstract][Full Text] [Related]  

  • 4. PAICS, a De Novo Purine Biosynthetic Enzyme, Is Overexpressed in Pancreatic Cancer and Is Involved in Its Progression.
    Agarwal S; Chakravarthi BVSK; Kim HG; Gupta N; Hale K; Balasubramanya SAH; Oliver PG; Thomas DG; Eltoum IA; Buchsbaum DJ; Manne U; Varambally S
    Transl Oncol; 2020 Jul; 13(7):100776. PubMed ID: 32422575
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Genetic and metabolomic analysis of AdeD and AdeI mutants of de novo purine biosynthesis: cellular models of de novo purine biosynthesis deficiency disorders.
    Duval N; Luhrs K; Wilkinson TG; Baresova V; Skopova V; Kmoch S; Vacano GN; Zikanova M; Patterson D
    Mol Genet Metab; 2013 Mar; 108(3):178-189. PubMed ID: 23394948
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Knockdown of PAICS inhibits malignant proliferation of human breast cancer cell lines.
    Meng M; Chen Y; Jia J; Li L; Yang S
    Biol Res; 2018 Aug; 51(1):24. PubMed ID: 30097015
    [TBL] [Abstract][Full Text] [Related]  

  • 7. PAICS, a Purine Nucleotide Metabolic Enzyme, is Involved in Tumor Growth and the Metastasis of Colorectal Cancer.
    Agarwal S; Chakravarthi BVSK; Behring M; Kim HG; Chandrashekar DS; Gupta N; Bajpai P; Elkholy A; Balasubramanya SAH; Hardy C; Diffalha SA; Varambally S; Manne U
    Cancers (Basel); 2020 Mar; 12(4):. PubMed ID: 32218208
    [TBL] [Abstract][Full Text] [Related]  

  • 8. PAICS deficiency, a new defect of de novo purine synthesis resulting in multiple congenital anomalies and fatal outcome.
    Pelet A; Skopova V; Steuerwald U; Baresova V; Zarhrate M; Plaza JM; Hnizda A; Krijt M; Souckova O; Wibrand F; Andorsdóttir G; Joensen F; Sedlak D; Bleyer AJ; Kmoch S; Lyonnet S; Zikanova M
    Hum Mol Genet; 2019 Nov; 28(22):3805-3814. PubMed ID: 31600779
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Zebrafish mutations in gart and paics identify crucial roles for de novo purine synthesis in vertebrate pigmentation and ocular development.
    Ng A; Uribe RA; Yieh L; Nuckels R; Gross JM
    Development; 2009 Aug; 136(15):2601-11. PubMed ID: 19570845
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Cadherin switches during epithelial-mesenchymal transition: CDH4/RCAD downregulation reduces bladder cancer progression.
    Martins-Lima C; Miranda-Gonçalves V; Lobo J; Constâncio V; Leite-Silva P; Guimarães-Teixeira C; Monteiro-Reis S; Sequeira JP; Cantante M; Gonçalves CS; Costa BM; Henrique R; Jerónimo C
    Cell Oncol (Dordr); 2022 Feb; 45(1):135-149. PubMed ID: 35064910
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Molecular Subtypes of Urothelial Bladder Cancer: Results from a Meta-cohort Analysis of 2411 Tumors.
    Tan TZ; Rouanne M; Tan KT; Huang RY; Thiery JP
    Eur Urol; 2019 Mar; 75(3):423-432. PubMed ID: 30213523
    [TBL] [Abstract][Full Text] [Related]  

  • 12. PAICS as a potential target for cancer therapy linking purine biosynthesis to cancer progression.
    Huo A; Xiong X
    Life Sci; 2023 Oct; 331():122070. PubMed ID: 37673296
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Downregulation of PAICS due to loss of chromosome 4q is associated with poor survival in stage III colorectal cancer.
    Kobayashi Y; Kumamoto K; Okayama H; Matsumoto T; Nakano H; Saito K; Matsumoto Y; Endo E; Kanke Y; Watanabe Y; Onozawa H; Fujita S; Sakamoto W; Saito M; Momma T; Takenoshita S; Kono K
    PLoS One; 2021; 16(2):e0247169. PubMed ID: 33596246
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Long non-coding RNA ZEB1-AS1 regulates miR-200b/FSCN1 signaling and enhances migration and invasion induced by TGF-β1 in bladder cancer cells.
    Gao R; Zhang N; Yang J; Zhu Y; Zhang Z; Wang J; Xu X; Li Z; Liu X; Li Z; Li J; Kong C; Bi J
    J Exp Clin Cancer Res; 2019 Mar; 38(1):111. PubMed ID: 30823924
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Multienzyme interactions of the de novo purine biosynthetic protein PAICS facilitate purinosome formation and metabolic channeling.
    He J; Zou LN; Pareek V; Benkovic SJ
    J Biol Chem; 2022 May; 298(5):101853. PubMed ID: 35331738
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Crystal structures of human PAICS reveal substrate and product binding of an emerging cancer target.
    Škerlová J; Unterlass J; Göttmann M; Marttila P; Homan E; Helleday T; Jemth AS; Stenmark P
    J Biol Chem; 2020 Aug; 295(33):11656-11668. PubMed ID: 32571877
    [TBL] [Abstract][Full Text] [Related]  

  • 17. PAICS contributes to gastric carcinogenesis and participates in DNA damage response by interacting with histone deacetylase 1/2.
    Huang N; Xu C; Deng L; Li X; Bian Z; Zhang Y; Long S; Chen Y; Zhen N; Li G; Sun F
    Cell Death Dis; 2020 Jul; 11(7):507. PubMed ID: 32632107
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Long non-coding RNA containing ultraconserved genomic region 8 promotes bladder cancer tumorigenesis.
    Olivieri M; Ferro M; Terreri S; Durso M; Romanelli A; Avitabile C; De Cobelli O; Messere A; Bruzzese D; Vannini I; Marinelli L; Novellino E; Zhang W; Incoronato M; Ilardi G; Staibano S; Marra L; Franco R; Perdonà S; Terracciano D; Czerniak B; Liguori GL; Colonna V; Fabbri M; Febbraio F; Calin GA; Cimmino A
    Oncotarget; 2016 Apr; 7(15):20636-54. PubMed ID: 26943042
    [TBL] [Abstract][Full Text] [Related]  

  • 19. TGF-β-induced transgelin promotes bladder cancer metastasis by regulating epithelial-mesenchymal transition and invadopodia formation.
    Chen Z; He S; Zhan Y; He A; Fang D; Gong Y; Li X; Zhou L
    EBioMedicine; 2019 Sep; 47():208-220. PubMed ID: 31420300
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Therapeutically actionable PAK4 is amplified, overexpressed, and involved in bladder cancer progression.
    Chandrashekar DS; Chakravarthi BVSK; Robinson AD; Anderson JC; Agarwal S; Balasubramanya SAH; Eich ML; Bajpai AK; Davuluri S; Guru MS; Guru AS; Naik G; Della Manna DL; Acharya KK; Carskadon S; Manne U; Crossman DK; Ferguson JE; Grizzle WE; Palanisamy N; Willey CD; Crowley MR; Netto GJ; Yang ES; Varambally S; Sonpavde G
    Oncogene; 2020 May; 39(20):4077-4091. PubMed ID: 32231273
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.