106 related articles for article (PubMed ID: 30128074)
1. Lead Optimization of 5-Aryl Benzimidazolone- and Oxindole-Based AMPA Receptor Modulators Selective for TARP γ-8.
Ravula S; Savall BM; Wu N; Lord B; Coe K; Wang K; Seierstad M; Swanson DM; Ziff J; Nguyen M; Leung P; Rynberg R; La D; Pippel DJ; Koudriakova T; Lovenberg TW; Carruthers NI; Maher MP; Ameriks MK
ACS Med Chem Lett; 2018 Aug; 9(8):821-826. PubMed ID: 30128074
[TBL] [Abstract][Full Text] [Related]
2. Influence of the TARP γ8-Selective Negative Allosteric Modulator JNJ-55511118 on AMPA Receptor Gating and Channel Conductance.
Coombs ID; Sexton CA; Cull-Candy SG; Farrant M
Mol Pharmacol; 2022 May; 101(5):343-356. PubMed ID: 35246481
[TBL] [Abstract][Full Text] [Related]
3. Characterizing the binding and function of TARP γ8-selective AMPA receptor modulators.
Dohrke JN; Watson JF; Birchall K; Greger IH
J Biol Chem; 2020 Oct; 295(43):14565-14577. PubMed ID: 32747446
[TBL] [Abstract][Full Text] [Related]
4. Discovery of the First α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptor Antagonist Dependent upon Transmembrane AMPA Receptor Regulatory Protein (TARP) γ-8.
Gardinier KM; Gernert DL; Porter WJ; Reel JK; Ornstein PL; Spinazze P; Stevens FC; Hahn P; Hollinshead SP; Mayhugh D; Schkeryantz J; Khilevich A; De Frutos O; Gleason SD; Kato AS; Luffer-Atlas D; Desai PV; Swanson S; Burris KD; Ding C; Heinz BA; Need AB; Barth VN; Stephenson GA; Diseroad BA; Woods TA; Yu H; Bredt D; Witkin JM
J Med Chem; 2016 May; 59(10):4753-68. PubMed ID: 27067148
[TBL] [Abstract][Full Text] [Related]
5. Synthesis, pharmacology and preclinical evaluation of
Chen Z; Mori W; Zhang X; Yamasaki T; Dunn PJ; Zhang G; Fu H; Shao T; Zhang Y; Hatori A; Ma L; Fujinaga M; Xie L; Deng X; Li H; Yu Q; Rong J; Josephson L; Ma JA; Shao Y; Tomita S; Zhang MR; Liang SH
Eur J Med Chem; 2018 Sep; 157():898-908. PubMed ID: 30145376
[TBL] [Abstract][Full Text] [Related]
6. Discovery of Imidazo[1,2-
Savall BM; Wu D; Swanson DM; Seierstad M; Wu N; Vives Martinez J; García Olmos B; Lord B; Coe K; Koudriakova T; Lovenberg TW; Carruthers NI; Maher MP; Ameriks MK
ACS Med Chem Lett; 2019 Mar; 10(3):267-272. PubMed ID: 30891124
[TBL] [Abstract][Full Text] [Related]
7. Inhibition of AMPA receptors (AMPARs) containing transmembrane AMPAR regulatory protein γ-8 with JNJ-55511118 shows preclinical efficacy in reducing chronic repetitive alcohol self-administration.
Hoffman JL; Faccidomo S; Saunders BL; Taylor SM; Kim M; Hodge CW
Alcohol Clin Exp Res; 2021 Jul; 45(7):1424-1435. PubMed ID: 34086361
[TBL] [Abstract][Full Text] [Related]
8. Negative modulation of AMPA receptors bound to transmembrane AMPA receptor regulatory protein γ-8 blunts the positive reinforcing properties of alcohol and sucrose in a brain region-dependent manner in male mice.
Hoffman JL; Faccidomo SP; Taylor SM; DeMiceli KG; May AM; Smith EN; Whindleton CM; Hodge CW
Psychopharmacology (Berl); 2023 Jun; 240(6):1261-1273. PubMed ID: 37055596
[TBL] [Abstract][Full Text] [Related]
9. Modulatory mechanisms of TARP γ8-selective AMPA receptor therapeutics.
Zhang D; Lape R; Shaikh SA; Kohegyi BK; Watson JF; Cais O; Nakagawa T; Greger IH
Nat Commun; 2023 Mar; 14(1):1659. PubMed ID: 36966141
[TBL] [Abstract][Full Text] [Related]
10. Structural and functional insights into transmembrane AMPA receptor regulatory protein complexes.
Twomey EC; Yelshanskaya MV; Sobolevsky AI
J Gen Physiol; 2019 Dec; 151(12):1347-1356. PubMed ID: 31615831
[TBL] [Abstract][Full Text] [Related]
11. Discovery and Characterization of AMPA Receptor Modulators Selective for TARP-γ8.
Maher MP; Wu N; Ravula S; Ameriks MK; Savall BM; Liu C; Lord B; Wyatt RM; Matta JA; Dugovic C; Yun S; Ver Donck L; Steckler T; Wickenden AD; Carruthers NI; Lovenberg TW
J Pharmacol Exp Ther; 2016 May; 357(2):394-414. PubMed ID: 26989142
[TBL] [Abstract][Full Text] [Related]
12. Differential regulation of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) receptor tetramerization by auxiliary subunits.
Certain N; Gan Q; Bennett J; Hsieh H; Wollmuth LP
bioRxiv; 2023 Feb; ():. PubMed ID: 36798164
[TBL] [Abstract][Full Text] [Related]
13. Inquiries into the Biological Significance of Transmembrane AMPA Receptor Regulatory Protein (TARP) γ-8 Through Investigations of TARP γ-8 Null Mice§.
Gleason SD; Kato A; Bui HH; Thompson LK; Valli SN; Stutz PV; Kuo MS; Falcone JF; Anderson WH; Li X; Witkin JM
CNS Neurol Disord Drug Targets; 2015; 14(5):612-26. PubMed ID: 25921737
[TBL] [Abstract][Full Text] [Related]
14. TARP γ-8 glycosylation regulates the surface expression of AMPA receptors.
Zheng CY; Chang K; Suh YH; Roche KW
Biochem J; 2015 Feb; 465(3):471-7. PubMed ID: 25495042
[TBL] [Abstract][Full Text] [Related]
15. TARP subtypes differentially and dose-dependently control synaptic AMPA receptor gating.
Milstein AD; Zhou W; Karimzadegan S; Bredt DS; Nicoll RA
Neuron; 2007 Sep; 55(6):905-18. PubMed ID: 17880894
[TBL] [Abstract][Full Text] [Related]
16. Imaging of Transmembrane AMPA Receptor Regulatory Proteins by Positron Emission Tomography.
Yu Q; Kumata K; Rong J; Chen Z; Yamasaki T; Chen J; Xiao Z; Ishii H; Hiraishi A; Shao T; Zhang Y; Hu K; Xie L; Fujinaga M; Zhao C; Mori W; Collier T; Haider A; Tomita S; Zhang MR; Liang S
J Med Chem; 2022 Jul; 65(13):9144-9158. PubMed ID: 35762919
[TBL] [Abstract][Full Text] [Related]
17. Molecular Mechanism of AMPA Receptor Modulation by TARP/Stargazin.
Ben-Yaacov A; Gillor M; Haham T; Parsai A; Qneibi M; Stern-Bach Y
Neuron; 2017 Mar; 93(5):1126-1137.e4. PubMed ID: 28238551
[TBL] [Abstract][Full Text] [Related]
18. Enhanced TARP-γ8-PSD-95 coupling in excitatory neurons contributes to the rapid antidepressant-like action of ketamine in male mice.
Xue SG; He JG; Lu LL; Song SJ; Chen MM; Wang F; Chen JG
Nat Commun; 2023 Dec; 14(1):7971. PubMed ID: 38042894
[TBL] [Abstract][Full Text] [Related]
19. TARP-associated AMPA receptors display an increased maximum channel conductance and multiple kinetically distinct open states.
Shelley C; Farrant M; Cull-Candy SG
J Physiol; 2012 Nov; 590(22):5723-38. PubMed ID: 22988139
[TBL] [Abstract][Full Text] [Related]
20. Preclinical Evaluation of Azabenzimidazole-Based PET Radioligands for γ-8 Dependent Transmembrane AMPA Receptor Regulatory Protein Imaging.
Chen J; Li Y; Yu Q; Patel JS; Zhou X; Zhang K; Rong J; Zhao C; Chaudhary AF; Zhang W; Bi C; Song Z; Davenport AT; Daunais JB; Haider A; Collier L; Yuan H; Liang S
Chembiochem; 2024 Mar; 25(6):e202300813. PubMed ID: 38227784
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]