BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

913 related articles for article (PubMed ID: 30131371)

  • 1. G protein-coupled receptor kinases (GRKs) orchestrate biased agonism at the β
    Choi M; Staus DP; Wingler LM; Ahn S; Pani B; Capel WD; Lefkowitz RJ
    Sci Signal; 2018 Aug; 11(544):. PubMed ID: 30131371
    [TBL] [Abstract][Full Text] [Related]  

  • 2. beta-arrestin-dependent, G protein-independent ERK1/2 activation by the beta2 adrenergic receptor.
    Shenoy SK; Drake MT; Nelson CD; Houtz DA; Xiao K; Madabushi S; Reiter E; Premont RT; Lichtarge O; Lefkowitz RJ
    J Biol Chem; 2006 Jan; 281(2):1261-73. PubMed ID: 16280323
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Gαs is dispensable for β-arrestin coupling but dictates GRK selectivity and is predominant for gene expression regulation by β2-adrenergic receptor.
    Burghi V; Paradis JS; Officer A; Adame-Garcia SR; Wu X; Matthees ESF; Barsi-Rhyne B; Ramms DJ; Clubb L; Acosta M; Tamayo P; Bouvier M; Inoue A; von Zastrow M; Hoffmann C; Gutkind JS
    J Biol Chem; 2023 Nov; 299(11):105293. PubMed ID: 37774973
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Distinct phosphorylation sites on the β(2)-adrenergic receptor establish a barcode that encodes differential functions of β-arrestin.
    Nobles KN; Xiao K; Ahn S; Shukla AK; Lam CM; Rajagopal S; Strachan RT; Huang TY; Bressler EA; Hara MR; Shenoy SK; Gygi SP; Lefkowitz RJ
    Sci Signal; 2011 Aug; 4(185):ra51. PubMed ID: 21868357
    [TBL] [Abstract][Full Text] [Related]  

  • 5. G Protein-Coupled Receptor Kinase 2 Selectively Enhances β-Arrestin Recruitment to the D
    Sánchez-Soto M; Boldizsar NM; Schardien KA; Madaras NS; Willette BKA; Inbody LR; Dasaro C; Moritz AE; Drube J; Haider RS; Free RB; Hoffman C; Sibley DR
    Biomolecules; 2023 Oct; 13(10):. PubMed ID: 37892234
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Reactive oxygen species are required for β2 adrenergic receptor-β-arrestin interactions and signaling to ERK1/2.
    Singh M; Moniri NH
    Biochem Pharmacol; 2012 Sep; 84(5):661-9. PubMed ID: 22728070
    [TBL] [Abstract][Full Text] [Related]  

  • 7. G-protein-coupled receptor kinase specificity for beta-arrestin recruitment to the beta2-adrenergic receptor revealed by fluorescence resonance energy transfer.
    Violin JD; Ren XR; Lefkowitz RJ
    J Biol Chem; 2006 Jul; 281(29):20577-88. PubMed ID: 16687412
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Sortase ligation enables homogeneous GPCR phosphorylation to reveal diversity in β-arrestin coupling.
    Staus DP; Wingler LM; Choi M; Pani B; Manglik A; Kruse AC; Lefkowitz RJ
    Proc Natl Acad Sci U S A; 2018 Apr; 115(15):3834-3839. PubMed ID: 29581292
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Different G protein-coupled receptor kinases govern G protein and beta-arrestin-mediated signaling of V2 vasopressin receptor.
    Ren XR; Reiter E; Ahn S; Kim J; Chen W; Lefkowitz RJ
    Proc Natl Acad Sci U S A; 2005 Feb; 102(5):1448-53. PubMed ID: 15671180
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Biased Signaling in Mutated Variants of β
    Madhu MK; Shewani K; Murarka RK
    J Chem Inf Model; 2024 Jan; 64(2):449-469. PubMed ID: 38194225
    [TBL] [Abstract][Full Text] [Related]  

  • 11. GPCR kinase knockout cells reveal the impact of individual GRKs on arrestin binding and GPCR regulation.
    Drube J; Haider RS; Matthees ESF; Reichel M; Zeiner J; Fritzwanker S; Ziegler C; Barz S; Klement L; Filor J; Weitzel V; Kliewer A; Miess-Tanneberg E; Kostenis E; Schulz S; Hoffmann C
    Nat Commun; 2022 Jan; 13(1):540. PubMed ID: 35087057
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The role of G protein-coupled receptor kinases in GLP-1R β-arrestin recruitment and internalisation.
    McNeill SM; Lu J; Marion C Carino C; Inoue A; Zhao P; Sexton PM; Wootten D
    Biochem Pharmacol; 2024 Apr; 222():116119. PubMed ID: 38461904
    [TBL] [Abstract][Full Text] [Related]  

  • 13. G protein-coupled receptor interactions with arrestins and GPCR kinases: The unresolved issue of signal bias.
    Chen Q; Tesmer JJG
    J Biol Chem; 2022 Sep; 298(9):102279. PubMed ID: 35863432
    [TBL] [Abstract][Full Text] [Related]  

  • 14. G-protein-coupled receptor (GPCR) kinase phosphorylation and beta-arrestin recruitment regulate the constitutive signaling activity of the human cytomegalovirus US28 GPCR.
    Miller WE; Houtz DA; Nelson CD; Kolattukudy PE; Lefkowitz RJ
    J Biol Chem; 2003 Jun; 278(24):21663-71. PubMed ID: 12668664
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Histamine H
    Michinaga S; Nagata A; Ogami R; Ogawa Y; Hishinuma S
    Int J Mol Sci; 2024 Mar; 25(6):. PubMed ID: 38542369
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Angiotensin type 1A receptor regulates β-arrestin binding of the β
    Tóth AD; Gyombolai P; Szalai B; Várnai P; Turu G; Hunyady L
    Mol Cell Endocrinol; 2017 Feb; 442():113-124. PubMed ID: 27908837
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Differential conformational requirements for activation of G proteins and the regulatory proteins arrestin and G protein-coupled receptor kinase in the G protein-coupled receptor for parathyroid hormone (PTH)/PTH-related protein.
    Vilardaga JP; Frank M; Krasel C; Dees C; Nissenson RA; Lohse MJ
    J Biol Chem; 2001 Sep; 276(36):33435-43. PubMed ID: 11387315
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Visualization of arrestin recruitment by a G-protein-coupled receptor.
    Shukla AK; Westfield GH; Xiao K; Reis RI; Huang LY; Tripathi-Shukla P; Qian J; Li S; Blanc A; Oleskie AN; Dosey AM; Su M; Liang CR; Gu LL; Shan JM; Chen X; Hanna R; Choi M; Yao XJ; Klink BU; Kahsai AW; Sidhu SS; Koide S; Penczek PA; Kossiakoff AA; Woods VL; Kobilka BK; Skiniotis G; Lefkowitz RJ
    Nature; 2014 Aug; 512(7513):218-222. PubMed ID: 25043026
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A structural basis for how ligand binding site changes can allosterically regulate GPCR signaling and engender functional selectivity.
    Sanchez-Soto M; Verma RK; Willette BKA; Gonye EC; Moore AM; Moritz AE; Boateng CA; Yano H; Free RB; Shi L; Sibley DR
    Sci Signal; 2020 Feb; 13(617):. PubMed ID: 32019899
    [TBL] [Abstract][Full Text] [Related]  

  • 20. GPCR kinases differentially modulate biased signaling downstream of CXCR3 depending on their subcellular localization.
    Gardner J; Eiger DS; Hicks C; Choi I; Pham U; Chundi A; Namjoshi O; Rajagopal S
    Sci Signal; 2024 Feb; 17(823):eadd9139. PubMed ID: 38349966
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 46.