168 related articles for article (PubMed ID: 30131393)
1. The Dysfunctional MDM2-p53 Axis in Adipocytes Contributes to Aging-Related Metabolic Complications by Induction of Lipodystrophy.
Liu Z; Jin L; Yang JK; Wang B; Wu KKL; Hallenborg P; Xu A; Cheng KKY
Diabetes; 2018 Nov; 67(11):2397-2409. PubMed ID: 30131393
[TBL] [Abstract][Full Text] [Related]
2. Tumor suppression and normal aging in mice with constitutively high p53 activity.
Mendrysa SM; O'Leary KA; McElwee MK; Michalowski J; Eisenman RN; Powell DA; Perry ME
Genes Dev; 2006 Jan; 20(1):16-21. PubMed ID: 16391230
[TBL] [Abstract][Full Text] [Related]
3. Relevance of the p53-MDM2 axis to aging.
Wu D; Prives C
Cell Death Differ; 2018 Jan; 25(1):169-179. PubMed ID: 29192902
[TBL] [Abstract][Full Text] [Related]
4. A novel mouse model of rhabdomyosarcoma underscores the dichotomy of MDM2-ALT1 function in vivo.
Comiskey DF; Jacob AG; Sanford BL; Montes M; Goodwin AK; Steiner H; Matsa E; Tapia-Santos AS; Bebee TW; Grieves J; La Perle K; Boyaka P; Chandler DS
Oncogene; 2018 Jan; 37(1):95-106. PubMed ID: 28892044
[TBL] [Abstract][Full Text] [Related]
5. Tempo-spatial alternative polyadenylation analysis reveals that 3' UTR lengthening of Mdm2 regulates p53 expression and cellular senescence in aged rat testis.
Wang L; Chen M; Fu H; Ni T; Wei G
Biochem Biophys Res Commun; 2020 Mar; 523(4):1046-1052. PubMed ID: 31973811
[TBL] [Abstract][Full Text] [Related]
6. Monitoring p53 by MDM2 and MDMX is required for endocrine pancreas development and function in a spatio-temporal manner.
Zhang Y; Zeng SX; Hao Q; Lu H
Dev Biol; 2017 Mar; 423(1):34-45. PubMed ID: 28118981
[TBL] [Abstract][Full Text] [Related]
7. Dysfunction of the MDM2/p53 axis is linked to premature aging.
Lessel D; Wu D; Trujillo C; Ramezani T; Lessel I; Alwasiyah MK; Saha B; Hisama FM; Rading K; Goebel I; Schütz P; Speit G; Högel J; Thiele H; Nürnberg G; Nürnberg P; Hammerschmidt M; Zhu Y; Tong DR; Katz C; Martin GM; Oshima J; Prives C; Kubisch C
J Clin Invest; 2017 Oct; 127(10):3598-3608. PubMed ID: 28846075
[TBL] [Abstract][Full Text] [Related]
8. UBTD1 induces cellular senescence through an UBTD1-Mdm2/p53 positive feedback loop.
Zhang XW; Wang XF; Ni SJ; Qin W; Zhao LQ; Hua RX; Lu YW; Li J; Dimri GP; Guo WJ
J Pathol; 2015 Mar; 235(4):656-67. PubMed ID: 25382750
[TBL] [Abstract][Full Text] [Related]
9. Mdm2 controls CREB-dependent transactivation and initiation of adipocyte differentiation.
Hallenborg P; Feddersen S; Francoz S; Murano I; Sundekilde U; Petersen RK; Akimov V; Olson MV; Lozano G; Cinti S; Gjertsen BT; Madsen L; Marine JC; Blagoev B; Kristiansen K
Cell Death Differ; 2012 Aug; 19(8):1381-9. PubMed ID: 22388350
[TBL] [Abstract][Full Text] [Related]
10. Adipose specific disruption of seipin causes early-onset generalised lipodystrophy and altered fuel utilisation without severe metabolic disease.
Mcilroy GD; Suchacki K; Roelofs AJ; Yang W; Fu Y; Bai B; Wallace RJ; De Bari C; Cawthorn WP; Han W; Delibegović M; Rochford JJ
Mol Metab; 2018 Apr; 10():55-65. PubMed ID: 29459250
[TBL] [Abstract][Full Text] [Related]
11. microRNA-1827 represses MDM2 to positively regulate tumor suppressor p53 and suppress tumorigenesis.
Zhang C; Liu J; Tan C; Yue X; Zhao Y; Peng J; Wang X; Laddha SV; Chan CS; Zheng S; Hu W; Feng Z
Oncotarget; 2016 Feb; 7(8):8783-96. PubMed ID: 26840028
[TBL] [Abstract][Full Text] [Related]
12. Protection against High-Fat-Diet-Induced Obesity in MDM2
Liu S; Kim TH; Franklin DA; Zhang Y
Cell Rep; 2017 Jan; 18(4):1005-1018. PubMed ID: 28122227
[TBL] [Abstract][Full Text] [Related]
13. Adipose MDM2 regulates systemic insulin sensitivity.
Hallenborg P; Jensen BAH; Fjære E; Petersen RK; Belmaâti MS; Rasmussen SS; Gunnarsson JP; Lauritzen P; Cheng KKY; Hermansson M; Sonne SB; Ejsing CS; Xu A; Kratchmarova I; Krüger M; Madsen L; Kristiansen K; Blagoev B
Sci Rep; 2021 Nov; 11(1):21839. PubMed ID: 34750429
[TBL] [Abstract][Full Text] [Related]
14. SRSF7 downregulation induces cellular senescence through generation of
Hong J; Min S; Yoon G; Lim SB
Aging (Albany NY); 2023 Dec; 15(24):14591-14606. PubMed ID: 38159247
[TBL] [Abstract][Full Text] [Related]
15. TRIAD1 inhibits MDM2-mediated p53 ubiquitination and degradation.
Bae S; Jung JH; Kim K; An IS; Kim SY; Lee JH; Park IC; Jin YW; Lee SJ; An S
FEBS Lett; 2012 Sep; 586(19):3057-63. PubMed ID: 22819825
[TBL] [Abstract][Full Text] [Related]
16. Osteoblast differentiation and skeletal development are regulated by Mdm2-p53 signaling.
Lengner CJ; Steinman HA; Gagnon J; Smith TW; Henderson JE; Kream BE; Stein GS; Lian JB; Jones SN
J Cell Biol; 2006 Mar; 172(6):909-21. PubMed ID: 16533949
[TBL] [Abstract][Full Text] [Related]
17. Accumulation of Smooth Muscle 22α Protein Accelerates Senescence of Vascular Smooth Muscle Cells via Stabilization of p53 In Vitro and In Vivo.
Miao SB; Xie XL; Yin YJ; Zhao LL; Zhang F; Shu YN; Chen R; Chen P; Dong LH; Lin YL; Lv P; Zhang DD; Nie X; Xue ZY; Han M
Arterioscler Thromb Vasc Biol; 2017 Oct; 37(10):1849-1859. PubMed ID: 28798142
[TBL] [Abstract][Full Text] [Related]
18. Age-Induced Changes in White, Brite, and Brown Adipose Depots: A Mini-Review.
Schosserer M; Grillari J; Wolfrum C; Scheideler M
Gerontology; 2018; 64(3):229-236. PubMed ID: 29212073
[TBL] [Abstract][Full Text] [Related]
19. Mir-660 is downregulated in lung cancer patients and its replacement inhibits lung tumorigenesis by targeting MDM2-p53 interaction.
Fortunato O; Boeri M; Moro M; Verri C; Mensah M; Conte D; Caleca L; Roz L; Pastorino U; Sozzi G
Cell Death Dis; 2014 Dec; 5(12):e1564. PubMed ID: 25501825
[TBL] [Abstract][Full Text] [Related]
20. Disruption of the RP-MDM2-p53 pathway accelerates APC loss-induced colorectal tumorigenesis.
Liu S; Tackmann NR; Yang J; Zhang Y
Oncogene; 2017 Mar; 36(10):1374-1383. PubMed ID: 27617574
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
