156 related articles for article (PubMed ID: 30133283)
1. Synergistic Effects of Stereochemistry and Appendages on the Performance Diversity of a Collection of Synthetic Compounds.
Melillo B; Zoller J; Hua BK; Verho O; Borghs JC; Nelson SD; Maetani M; Wawer MJ; Clemons PA; Schreiber SL
J Am Chem Soc; 2018 Sep; 140(37):11784-11790. PubMed ID: 30133283
[TBL] [Abstract][Full Text] [Related]
2. Multiple Chemical Features Impact Biological Performance Diversity of a Highly Active Natural Product-Inspired Library.
Hippman RS; Pavlinov I; Gao Q; Mavlyanova MK; Gerlach EM; Aldrich LN
Chembiochem; 2020 Nov; 21(21):3137-3145. PubMed ID: 32558167
[TBL] [Abstract][Full Text] [Related]
3. Synthesis and profiling of a diverse collection of azetidine-based scaffolds for the development of CNS-focused lead-like libraries.
Lowe JT; Lee MD; Akella LB; Davoine E; Donckele EJ; Durak L; Duvall JR; Gerard B; Holson EB; Joliton A; Kesavan S; Lemercier BC; Liu H; Marié JC; Mulrooney CA; Muncipinto G; Welzel-O'Shea M; Panko LM; Rowley A; Suh BC; Thomas M; Wagner FF; Wei J; Foley MA; Marcaurelle LA
J Org Chem; 2012 Sep; 77(17):7187-211. PubMed ID: 22853001
[TBL] [Abstract][Full Text] [Related]
4. Diversity-Oriented Library Synthesis from Steviol and Isosteviol-Derived Scaffolds.
Holth TAD; Walters MA; Hutt OE; Georg GI
ACS Comb Sci; 2020 Mar; 22(3):150-155. PubMed ID: 32065745
[TBL] [Abstract][Full Text] [Related]
5. DNA Barcoding a Complete Matrix of Stereoisomeric Small Molecules.
Gerry CJ; Wawer MJ; Clemons PA; Schreiber SL
J Am Chem Soc; 2019 Jul; 141(26):10225-10235. PubMed ID: 31184885
[TBL] [Abstract][Full Text] [Related]
6. A practical method for targeted library design balancing lead-like properties with diversity.
Stocks MJ; Wilden GR; Pairaudeau G; Perry MW; Steele J; Stonehouse JP
ChemMedChem; 2009 May; 4(5):800-8. PubMed ID: 19360802
[TBL] [Abstract][Full Text] [Related]
7. Using biological performance similarity to inform disaccharide library design.
Tanikawa T; Fridman M; Zhu W; Faulk B; Joseph IC; Kahne D; Wagner BK; Clemons PA
J Am Chem Soc; 2009 Apr; 131(14):5075-83. PubMed ID: 19298063
[TBL] [Abstract][Full Text] [Related]
8. Systematic Diversity-Oriented Synthesis of Reduced Flavones from γ-Pyrones to Probe Biological Performance Diversity.
Gerlach EM; Korkmaz MA; Pavlinov I; Gao Q; Aldrich LN
ACS Chem Biol; 2019 Jul; 14(7):1536-1545. PubMed ID: 31184855
[TBL] [Abstract][Full Text] [Related]
9. Real-Time Biological Annotation of Synthetic Compounds.
Gerry CJ; Hua BK; Wawer MJ; Knowles JP; Nelson SD; Verho O; Dandapani S; Wagner BK; Clemons PA; Booker-Milburn KI; Boskovic ZV; Schreiber SL
J Am Chem Soc; 2016 Jul; 138(28):8920-7. PubMed ID: 27398798
[TBL] [Abstract][Full Text] [Related]
10. Next generation diversity-oriented synthesis: a paradigm shift from chemical diversity to biological diversity.
Pavlinov I; Gerlach EM; Aldrich LN
Org Biomol Chem; 2019 Feb; 17(7):1608-1623. PubMed ID: 30328455
[TBL] [Abstract][Full Text] [Related]
11. [Structural diversity oriented synthesis to explore the living world].
Wong YS
Med Sci (Paris); 2015 Jan; 31(1):93-7. PubMed ID: 25658736
[TBL] [Abstract][Full Text] [Related]
12. Access to a Structurally Complex Compound Collection via Ring Distortion of the Alkaloid Sinomenine.
Garcia A; Drown BS; Hergenrother PJ
Org Lett; 2016 Oct; 18(19):4852-4855. PubMed ID: 27650404
[TBL] [Abstract][Full Text] [Related]
13. A concise route to the highly-functionalized azetidine precursor: the enantioselective synthesis of penaresidin B.
Ding F; William R; Kock SM; Leow ML; Liu XW
Chem Commun (Camb); 2015 Mar; 51(22):4639-42. PubMed ID: 25692188
[TBL] [Abstract][Full Text] [Related]
14. Polymer supported synthesis of a natural product-inspired oxepane library.
Basu S; Waldmann H
Bioorg Med Chem; 2014 Aug; 22(16):4430-44. PubMed ID: 24947480
[TBL] [Abstract][Full Text] [Related]
15. Stereocontrolled synthesis of substituted N-arenesulfonyl azetidines from gamma-(phenylseleno)alkyl arylsulfonamides.
Tiecco M; Testaferri L; Temperini A; Terlizzi R; Bagnoli L; Marini F; Santi C
Org Biomol Chem; 2007 Nov; 5(21):3510-9. PubMed ID: 17943211
[TBL] [Abstract][Full Text] [Related]
16. Synthesis of novel angular spirocyclic azetidines.
Guérot C; Tchitchanov BH; Knust H; Carreira EM
Org Lett; 2011 Feb; 13(4):780-3. PubMed ID: 21235246
[TBL] [Abstract][Full Text] [Related]
17. Construction of polyheterocyclic benzopyran library with diverse core skeletons through diversity-oriented synthesis pathway: part II.
Zhu M; Lim BJ; Koh M; Park SB
ACS Comb Sci; 2012 Feb; 14(2):124-34. PubMed ID: 22181986
[TBL] [Abstract][Full Text] [Related]
18. Diversity-Oriented Synthesis of Libraries Based on Benzofuran and 2,3-Dihydrobenzofuran Scaffolds.
Qin L; Vo DD; Nakhai A; Andersson CD; Elofsson M
ACS Comb Sci; 2017 Jun; 19(6):370-376. PubMed ID: 28306238
[TBL] [Abstract][Full Text] [Related]
19. Diversity by divergence: Solution-phase parallel synthesis of a library of N-diversified 1-oxa-7-azaspiro[4.5]decan-2-yl-propanes and -butanes.
Kumar S; Thornton PD; Santini C
ACS Comb Sci; 2013 Nov; 15(11):564-71. PubMed ID: 24079459
[TBL] [Abstract][Full Text] [Related]
20. Stereoselective construction of highly functionalized azetidines via a [2 + 2]-cycloaddition.
Ye Y; Wang H; Fan R
Org Lett; 2010 Jun; 12(12):2802-5. PubMed ID: 20469873
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]