317 related articles for article (PubMed ID: 30134653)
1. PADFrag: A Database Built for the Exploration of Bioactive Fragment Space for Drug Discovery.
Yang JF; Wang F; Jiang W; Zhou GY; Li CZ; Zhu XL; Hao GF; Yang GF
J Chem Inf Model; 2018 Sep; 58(9):1725-1730. PubMed ID: 30134653
[TBL] [Abstract][Full Text] [Related]
2. ACFIS: a web server for fragment-based drug discovery.
Hao GF; Jiang W; Ye YN; Wu FX; Zhu XL; Guo FB; Yang GF
Nucleic Acids Res; 2016 Jul; 44(W1):W550-6. PubMed ID: 27150808
[TBL] [Abstract][Full Text] [Related]
3. Towards systematic exploration of chemical space: building the fragment library module in molecular property diagnostic suite.
Gaur AS; John L; Kumar N; Vivek MR; Nagamani S; Mahanta HJ; Sastry GN
Mol Divers; 2023 Jun; 27(3):1459-1468. PubMed ID: 35925528
[TBL] [Abstract][Full Text] [Related]
4. How Size Matters: Diversity for Fragment Library Design.
Shi Y; von Itzstein M
Molecules; 2019 Aug; 24(15):. PubMed ID: 31387220
[TBL] [Abstract][Full Text] [Related]
5. Charting, navigating, and populating natural product chemical space for drug discovery.
Lachance H; Wetzel S; Kumar K; Waldmann H
J Med Chem; 2012 Jul; 55(13):5989-6001. PubMed ID: 22537178
[TBL] [Abstract][Full Text] [Related]
6. From fragment screening to potent binders: strategies for fragment-to-lead evolution.
Eitner K; Koch U
Mini Rev Med Chem; 2009 Jul; 9(8):956-61. PubMed ID: 19601891
[TBL] [Abstract][Full Text] [Related]
7. Enriching screening libraries with bioactive fragment space.
Zhang N; Zhao H
Bioorg Med Chem Lett; 2016 Aug; 26(15):3594-7. PubMed ID: 27311891
[TBL] [Abstract][Full Text] [Related]
8. SAR Matrix Method for Large-Scale Analysis of Compound Structure-Activity Relationships and Exploration of Multitarget Activity Spaces.
Hu Y; Bajorath J
Methods Mol Biol; 2018; 1825():339-352. PubMed ID: 30334212
[TBL] [Abstract][Full Text] [Related]
9. Computational tools for in silico fragment-based drug design.
Mortier J; Rakers C; Frederick R; Wolber G
Curr Top Med Chem; 2012; 12(17):1935-43. PubMed ID: 23116473
[TBL] [Abstract][Full Text] [Related]
10. DrugSpaceX: a large screenable and synthetically tractable database extending drug space.
Yang T; Li Z; Chen Y; Feng D; Wang G; Fu Z; Ding X; Tan X; Zhao J; Luo X; Chen K; Jiang H; Zheng M
Nucleic Acids Res; 2021 Jan; 49(D1):D1170-D1178. PubMed ID: 33104791
[TBL] [Abstract][Full Text] [Related]
11. Privileged structures: efficient chemical "navigators" toward unexplored biologically relevant chemical spaces.
Kim J; Kim H; Park SB
J Am Chem Soc; 2014 Oct; 136(42):14629-38. PubMed ID: 25310802
[TBL] [Abstract][Full Text] [Related]
12. Using fragment-based technologies to target protein-protein interactions.
Bower JF; Pannifer A
Curr Pharm Des; 2012; 18(30):4685-96. PubMed ID: 22650253
[TBL] [Abstract][Full Text] [Related]
13. From Protein Structure to Small-Molecules: Recent Advances and Applications to Fragment-Based Drug Discovery.
Ferreira LG; Andricopulo AD
Curr Top Med Chem; 2017; 17(20):2260-2270. PubMed ID: 28240184
[TBL] [Abstract][Full Text] [Related]
14. Counting on Fragment Based Drug Design Approach for Drug Discovery.
Kashyap A; Singh PK; Silakari O
Curr Top Med Chem; 2018; 18(27):2284-2293. PubMed ID: 30499406
[TBL] [Abstract][Full Text] [Related]
15. Natural-product-derived fragments for fragment-based ligand discovery.
Over B; Wetzel S; Grütter C; Nakai Y; Renner S; Rauh D; Waldmann H
Nat Chem; 2013 Jan; 5(1):21-8. PubMed ID: 23247173
[TBL] [Abstract][Full Text] [Related]
16. Efficient search of chemical space: navigating from fragments to structurally diverse chemotypes.
Wassermann AM; Kutchukian PS; Lounkine E; Luethi T; Hamon J; Bocker MT; Malik HA; Cowan-Jacob SW; Glick M
J Med Chem; 2013 Nov; 56(21):8879-91. PubMed ID: 24117015
[TBL] [Abstract][Full Text] [Related]
17. Fragment library design: using cheminformatics and expert chemists to fill gaps in existing fragment libraries.
Kutchukian PS; So SS; Fischer C; Waller CL
Methods Mol Biol; 2015; 1289():43-53. PubMed ID: 25709032
[TBL] [Abstract][Full Text] [Related]
18. Fragment-Based Ligand Designing.
Katiyar SP; Malik V; Kumari A; Singh K; Sundar D
Methods Mol Biol; 2018; 1762():123-144. PubMed ID: 29594771
[TBL] [Abstract][Full Text] [Related]
19. Fragment based lead discovery of small molecule inhibitors for the EPHA4 receptor tyrosine kinase.
van Linden OP; Farenc C; Zoutman WH; Hameetman L; Wijtmans M; Leurs R; Tensen CP; Siegal G; de Esch IJ
Eur J Med Chem; 2012 Jan; 47(1):493-500. PubMed ID: 22137457
[TBL] [Abstract][Full Text] [Related]
20. Fragment-based ligand discovery.
Fischer M; Hubbard RE
Mol Interv; 2009 Feb; 9(1):22-30. PubMed ID: 19299661
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]