BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

233 related articles for article (PubMed ID: 30135211)

  • 1. Peptide-MHC (pMHC) binding to a human antiviral T cell receptor induces long-range allosteric communication between pMHC- and CD3-binding sites.
    Rangarajan S; He Y; Chen Y; Kerzic MC; Ma B; Gowthaman R; Pierce BG; Nussinov R; Mariuzza RA; Orban J
    J Biol Chem; 2018 Oct; 293(41):15991-16005. PubMed ID: 30135211
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Peptide-MHC Binding Reveals Conserved Allosteric Sites in MHC Class I- and Class II-Restricted T Cell Receptors (TCRs).
    He Y; Agnihotri P; Rangarajan S; Chen Y; Kerzic MC; Ma B; Nussinov R; Mariuzza RA; Orban J
    J Mol Biol; 2020 Dec; 432(24):166697. PubMed ID: 33157083
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The Full Model of the pMHC-TCR-CD3 Complex: A Structural and Dynamical Characterization of Bound and Unbound States.
    Alba J; D'Abramo M
    Cells; 2022 Feb; 11(4):. PubMed ID: 35203317
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Identification of the Docking Site for CD3 on the T Cell Receptor β Chain by Solution NMR.
    He Y; Rangarajan S; Kerzic M; Luo M; Chen Y; Wang Q; Yin Y; Workman CJ; Vignali KM; Vignali DA; Mariuzza RA; Orban J
    J Biol Chem; 2015 Aug; 290(32):19796-805. PubMed ID: 26109064
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Identification of a common docking topology with substantial variation among different TCR-peptide-MHC complexes.
    Teng MK; Smolyar A; Tse AG; Liu JH; Liu J; Hussey RE; Nathenson SG; Chang HC; Reinherz EL; Wang JH
    Curr Biol; 1998 Mar; 8(7):409-12. PubMed ID: 9545202
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The structural basis of T-cell receptor (TCR) activation: An enduring enigma.
    Mariuzza RA; Agnihotri P; Orban J
    J Biol Chem; 2020 Jan; 295(4):914-925. PubMed ID: 31848223
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The
    Hwang W; Mallis RJ; Lang MJ; Reinherz EL
    Proc Natl Acad Sci U S A; 2020 Sep; 117(35):21336-21345. PubMed ID: 32796106
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The T-Cell Receptor Can Bind to the Peptide-Bound Major Histocompatibility Complex and Uncomplexed β
    Merkle PS; Irving M; Hongjian S; Ferber M; Jørgensen TJD; Scholten K; Luescher I; Coukos G; Zoete V; Cuendet MA; Michielin O; Rand KD
    Biochemistry; 2017 Aug; 56(30):3945-3961. PubMed ID: 28671821
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Conformational melding permits a conserved binding geometry in TCR recognition of foreign and self molecular mimics.
    Borbulevych OY; Piepenbrink KH; Baker BM
    J Immunol; 2011 Mar; 186(5):2950-8. PubMed ID: 21282516
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A comprehensive calorimetric investigation of an entropically driven T cell receptor-peptide/major histocompatibility complex interaction.
    Armstrong KM; Baker BM
    Biophys J; 2007 Jul; 93(2):597-609. PubMed ID: 17449678
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Not just another Fab: the crystal structure of a TcR-MHC-peptide complex.
    Jardetzky T
    Structure; 1997 Feb; 5(2):159-63. PubMed ID: 9032079
    [TBL] [Abstract][Full Text] [Related]  

  • 12. An allosteric site in the T-cell receptor Cβ domain plays a critical signalling role.
    Natarajan K; McShan AC; Jiang J; Kumirov VK; Wang R; Zhao H; Schuck P; Tilahun ME; Boyd LF; Ying J; Bax A; Margulies DH; Sgourakis NG
    Nat Commun; 2017 May; 8():15260. PubMed ID: 28508865
    [TBL] [Abstract][Full Text] [Related]  

  • 13. An alphabeta T cell receptor structure at 2.5 A and its orientation in the TCR-MHC complex.
    Garcia KC; Degano M; Stanfield RL; Brunmark A; Jackson MR; Peterson PA; Teyton L; Wilson IA
    Science; 1996 Oct; 274(5285):209-19. PubMed ID: 8824178
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Two human T cell receptors bind in a similar diagonal mode to the HLA-A2/Tax peptide complex using different TCR amino acids.
    Ding YH; Smith KJ; Garboczi DN; Utz U; Biddison WE; Wiley DC
    Immunity; 1998 Apr; 8(4):403-11. PubMed ID: 9586631
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Intramolecular Domain Movements of Free and Bound pMHC and TCR Proteins: A Molecular Dynamics Simulation Study.
    Karch R; Stocsits C; Ilieva N; Schreiner W
    Cells; 2019 Jul; 8(7):. PubMed ID: 31337065
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Allosteric changes in the TCR/CD3 structure upon interaction with extra- or intra-cellular ligands.
    Rubin B; Knibiehler M; Gairin JE
    Scand J Immunol; 2007; 66(2-3):228-37. PubMed ID: 17635800
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Mechano-regulation of Peptide-MHC Class I Conformations Determines TCR Antigen Recognition.
    Wu P; Zhang T; Liu B; Fei P; Cui L; Qin R; Zhu H; Yao D; Martinez RJ; Hu W; An C; Zhang Y; Liu J; Shi J; Fan J; Yin W; Sun J; Zhou C; Zeng X; Xu C; Wang J; Evavold BD; Zhu C; Chen W; Lou J
    Mol Cell; 2019 Mar; 73(5):1015-1027.e7. PubMed ID: 30711376
    [TBL] [Abstract][Full Text] [Related]  

  • 18. T cell receptor engagement by peptide-MHC ligands induces a conformational change in the CD3 complex of thymocytes.
    Gil D; Schrum AG; Alarcón B; Palmer E
    J Exp Med; 2005 Feb; 201(4):517-22. PubMed ID: 15728235
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Assembly, specific binding, and crystallization of a human TCR-alphabeta with an antigenic Tax peptide from human T lymphotropic virus type 1 and the class I MHC molecule HLA-A2.
    Garboczi DN; Utz U; Ghosh P; Seth A; Kim J; VanTienhoven EA; Biddison WE; Wiley DC
    J Immunol; 1996 Dec; 157(12):5403-10. PubMed ID: 8955188
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Antigen ligation triggers a conformational change within the constant domain of the alphabeta T cell receptor.
    Beddoe T; Chen Z; Clements CS; Ely LK; Bushell SR; Vivian JP; Kjer-Nielsen L; Pang SS; Dunstone MA; Liu YC; Macdonald WA; Perugini MA; Wilce MC; Burrows SR; Purcell AW; Tiganis T; Bottomley SP; McCluskey J; Rossjohn J
    Immunity; 2009 Jun; 30(6):777-88. PubMed ID: 19464197
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.