414 related articles for article (PubMed ID: 30137266)
1. Structural and Functional Biology of Aldo-Keto Reductase Steroid-Transforming Enzymes.
Penning TM; Wangtrakuldee P; Auchus RJ
Endocr Rev; 2019 Apr; 40(2):447-475. PubMed ID: 30137266
[TBL] [Abstract][Full Text] [Related]
2. Stereospecific reduction of 5β-reduced steroids by human ketosteroid reductases of the AKR (aldo-keto reductase) superfamily: role of AKR1C1-AKR1C4 in the metabolism of testosterone and progesterone via the 5β-reductase pathway.
Jin Y; Mesaros AC; Blair IA; Penning TM
Biochem J; 2011 Jul; 437(1):53-61. PubMed ID: 21521174
[TBL] [Abstract][Full Text] [Related]
3. Role of aldo-keto reductase family 1 (AKR1) enzymes in human steroid metabolism.
Rižner TL; Penning TM
Steroids; 2014 Jan; 79():49-63. PubMed ID: 24189185
[TBL] [Abstract][Full Text] [Related]
4. The aldo-keto reductases (AKRs): Overview.
Penning TM
Chem Biol Interact; 2015 Jun; 234():236-46. PubMed ID: 25304492
[TBL] [Abstract][Full Text] [Related]
5. Engineering steroid hormone specificity into aldo-keto reductases.
Penning TM; Ma H; Jez JM
Chem Biol Interact; 2001 Jan; 130-132(1-3):659-71. PubMed ID: 11306084
[TBL] [Abstract][Full Text] [Related]
6. Human dehydrogenase/reductase SDR family member 11 (DHRS11) and aldo-keto reductase 1C isoforms in comparison: Substrate and reaction specificity in the reduction of 11-keto-C
Endo S; Morikawa Y; Kudo Y; Suenami K; Matsunaga T; Ikari A; Hara A
J Steroid Biochem Mol Biol; 2020 May; 199():105586. PubMed ID: 31926269
[TBL] [Abstract][Full Text] [Related]
7. Human and murine steroid 5β-reductases (AKR1D1 and AKR1D4): insights into the role of the catalytic glutamic acid.
Chen M; Wangtrakuldee P; Zang T; Duan L; Gathercole LL; Tomlinson JW; Penning TM
Chem Biol Interact; 2019 May; 305():163-170. PubMed ID: 30928400
[TBL] [Abstract][Full Text] [Related]
8. Germline Mutations in Steroid Metabolizing Enzymes: A Focus on Steroid Transforming Aldo-Keto Reductases.
Detlefsen AJ; Paulukinas RD; Penning TM
Int J Mol Sci; 2023 Jan; 24(3):. PubMed ID: 36768194
[TBL] [Abstract][Full Text] [Related]
9. Conversion of human steroid 5β-reductase (AKR1D1) into 3β-hydroxysteroid dehydrogenase by single point mutation E120H: example of perfect enzyme engineering.
Chen M; Drury JE; Christianson DW; Penning TM
J Biol Chem; 2012 May; 287(20):16609-22. PubMed ID: 22437839
[TBL] [Abstract][Full Text] [Related]
10. Porcine aldo-keto reductase 1C subfamily members AKR1C1 and AKR1C4: Substrate specificity, inhibitor sensitivity and activators.
Endo S; Morikawa Y; Matsunaga T; Hara A; Nishinaka T
J Steroid Biochem Mol Biol; 2022 Jul; 221():106113. PubMed ID: 35398259
[TBL] [Abstract][Full Text] [Related]
11. 5β-Reduced steroids and human Δ(4)-3-ketosteroid 5β-reductase (AKR1D1).
Chen M; Penning TM
Steroids; 2014 May; 83():17-26. PubMed ID: 24513054
[TBL] [Abstract][Full Text] [Related]
12. Molecular determinants of steroid recognition and catalysis in aldo-keto reductases. Lessons from 3alpha-hydroxysteroid dehydrogenase.
Penning TM
J Steroid Biochem Mol Biol; 1999; 69(1-6):211-25. PubMed ID: 10418995
[TBL] [Abstract][Full Text] [Related]
13. Promiscuity and diversity in 3-ketosteroid reductases.
Penning TM; Chen M; Jin Y
J Steroid Biochem Mol Biol; 2015 Jul; 151():93-101. PubMed ID: 25500069
[TBL] [Abstract][Full Text] [Related]
14. The rate-determining steps of aldo-keto reductases (AKRs), a study on human steroid 5β-reductase (AKR1D1).
Chen M; Jin Y; Penning TM
Chem Biol Interact; 2015 Jun; 234():360-5. PubMed ID: 25500266
[TBL] [Abstract][Full Text] [Related]
15. Mouse 17alpha-hydroxysteroid dehydrogenase (AKR1C21) binds steroids differently from other aldo-keto reductases: identification and characterization of amino acid residues critical for substrate binding.
Faucher F; Cantin L; Pereira de Jésus-Tran K; Lemieux M; Luu-The V; Labrie F; Breton R
J Mol Biol; 2007 Jun; 369(2):525-40. PubMed ID: 17442338
[TBL] [Abstract][Full Text] [Related]
16. Human type 3 3alpha-hydroxysteroid dehydrogenase (aldo-keto reductase 1C2) and androgen metabolism in prostate cells.
Rizner TL; Lin HK; Peehl DM; Steckelbroeck S; Bauman DR; Penning TM
Endocrinology; 2003 Jul; 144(7):2922-32. PubMed ID: 12810547
[TBL] [Abstract][Full Text] [Related]
17. The roles of aldo-keto reductases in steroid hormone action.
Bauman DR; Steckelbroeck S; Penning TM
Drug News Perspect; 2004 Nov; 17(9):563-78. PubMed ID: 15645014
[TBL] [Abstract][Full Text] [Related]
18. Engineering aldo-keto reductase 1B10 to mimic the distinct 1B15 topology and specificity towards inhibitors and substrates, including retinoids and steroids.
Giménez-Dejoz J; Weber S; Fernández-Pardo Á; Möller G; Adamski J; Porté S; Parés X; Farrés J
Chem Biol Interact; 2019 Jul; 307():186-194. PubMed ID: 31028727
[TBL] [Abstract][Full Text] [Related]
19. Structure and function of 3 alpha-hydroxysteroid dehydrogenase.
Penning TM; Bennett MJ; Smith-Hoog S; Schlegel BP; Jez JM; Lewis M
Steroids; 1997 Jan; 62(1):101-11. PubMed ID: 9029723
[TBL] [Abstract][Full Text] [Related]
20. Aldo keto-reductase family 1C members 1 through 4 recombinant enzyme purification and enzyme assay.
Detlefsen AJ
Methods Enzymol; 2023; 689():303-329. PubMed ID: 37802576
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]