BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

252 related articles for article (PubMed ID: 30145931)

  • 1. Pathological missorting of endogenous MAPT/Tau in neurons caused by failure of protein degradation systems.
    Balaji V; Kaniyappan S; Mandelkow E; Wang Y; Mandelkow EM
    Autophagy; 2018; 14(12):2139-2154. PubMed ID: 30145931
    [TBL] [Abstract][Full Text] [Related]  

  • 2. BAG3 and SYNPO (synaptopodin) facilitate phospho-MAPT/Tau degradation via autophagy in neuronal processes.
    Ji C; Tang M; Zeidler C; Höhfeld J; Johnson GV
    Autophagy; 2019 Jul; 15(7):1199-1213. PubMed ID: 30744518
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Decrease of neuronal FKBP4/FKBP52 modulates perinuclear lysosomal positioning and MAPT/Tau behavior during MAPT/Tau-induced proteotoxic stress.
    Chambraud B; Daguinot C; Guillemeau K; Genet M; Dounane O; Meduri G; Poüs C; Baulieu EE; Giustiniani J
    Autophagy; 2021 Nov; 17(11):3491-3510. PubMed ID: 33459145
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Abeta oligomers cause localized Ca(2+) elevation, missorting of endogenous Tau into dendrites, Tau phosphorylation, and destruction of microtubules and spines.
    Zempel H; Thies E; Mandelkow E; Mandelkow EM
    J Neurosci; 2010 Sep; 30(36):11938-50. PubMed ID: 20826658
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Tau missorting and spastin-induced microtubule disruption in neurodegeneration: Alzheimer Disease and Hereditary Spastic Paraplegia.
    Zempel H; Mandelkow EM
    Mol Neurodegener; 2015 Dec; 10():68. PubMed ID: 26691836
    [TBL] [Abstract][Full Text] [Related]  

  • 6. MAPT/Tau accumulation represses autophagy flux by disrupting IST1-regulated ESCRT-III complex formation: a vicious cycle in Alzheimer neurodegeneration.
    Feng Q; Luo Y; Zhang XN; Yang XF; Hong XY; Sun DS; Li XC; Hu Y; Li XG; Zhang JF; Li X; Yang Y; Wang Q; Liu GP; Wang JZ
    Autophagy; 2020 Apr; 16(4):641-658. PubMed ID: 31223056
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The cargo receptor SQSTM1 ameliorates neurofibrillary tangle pathology and spreading through selective targeting of pathological MAPT (microtubule associated protein tau).
    Xu Y; Zhang S; Zheng H
    Autophagy; 2019 Apr; 15(4):583-598. PubMed ID: 30290707
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Axodendritic sorting and pathological missorting of Tau are isoform-specific and determined by axon initial segment architecture.
    Zempel H; Dennissen FJA; Kumar Y; Luedtke J; Biernat J; Mandelkow EM; Mandelkow E
    J Biol Chem; 2017 Jul; 292(29):12192-12207. PubMed ID: 28536263
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Lost after translation: missorting of Tau protein and consequences for Alzheimer disease.
    Zempel H; Mandelkow E
    Trends Neurosci; 2014 Dec; 37(12):721-32. PubMed ID: 25223701
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Tau phosphorylation affects its axonal transport and degradation.
    Rodríguez-Martín T; Cuchillo-Ibáñez I; Noble W; Nyenya F; Anderton BH; Hanger DP
    Neurobiol Aging; 2013 Sep; 34(9):2146-57. PubMed ID: 23601672
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Missorting of tau in neurons causes degeneration of synapses that can be rescued by the kinase MARK2/Par-1.
    Thies E; Mandelkow EM
    J Neurosci; 2007 Mar; 27(11):2896-907. PubMed ID: 17360912
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Microfluidic Chamber Technology to Study Missorting and Spreading of Tau Protein in Alzheimer's Disease.
    Kaniyappan S; Balaji V; Wang Y; Mandelkow E
    Methods Mol Biol; 2023; 2551():111-123. PubMed ID: 36310200
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Tau protein is essential for stress-induced brain pathology.
    Lopes S; Vaz-Silva J; Pinto V; Dalla C; Kokras N; Bedenk B; Mack N; Czisch M; Almeida OF; Sousa N; Sotiropoulos I
    Proc Natl Acad Sci U S A; 2016 Jun; 113(26):E3755-63. PubMed ID: 27274066
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Linking amyloid-β and tau: amyloid-β induced synaptic dysfunction via local wreckage of the neuronal cytoskeleton.
    Zempel H; Mandelkow EM
    Neurodegener Dis; 2012; 10(1-4):64-72. PubMed ID: 22156588
    [TBL] [Abstract][Full Text] [Related]  

  • 15. AMPK activation regulates neuronal structure in developing hippocampal neurons.
    Ramamurthy S; Chang E; Cao Y; Zhu J; Ronnett GV
    Neuroscience; 2014 Feb; 259():13-24. PubMed ID: 24295634
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A mitochondria cluster at the proximal axon initial segment controls axodendritic TAU trafficking in rodent primary and human iPSC-derived neurons.
    Tjiang N; Zempel H
    Cell Mol Life Sci; 2022 Feb; 79(2):120. PubMed ID: 35119496
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Amyloid-β oligomers induce synaptic damage via Tau-dependent microtubule severing by TTLL6 and spastin.
    Zempel H; Luedtke J; Kumar Y; Biernat J; Dawson H; Mandelkow E; Mandelkow EM
    EMBO J; 2013 Nov; 32(22):2920-37. PubMed ID: 24065130
    [TBL] [Abstract][Full Text] [Related]  

  • 18. UBE4B, a microRNA-9 target gene, promotes autophagy-mediated Tau degradation.
    Subramanian M; Hyeon SJ; Das T; Suh YS; Kim YK; Lee JS; Song EJ; Ryu H; Yu K
    Nat Commun; 2021 Jun; 12(1):3291. PubMed ID: 34078905
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Autophagic degradation of tau in primary neurons and its enhancement by trehalose.
    Krüger U; Wang Y; Kumar S; Mandelkow EM
    Neurobiol Aging; 2012 Oct; 33(10):2291-305. PubMed ID: 22169203
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Characterisation of cytoskeletal abnormalities in mice transgenic for wild-type human tau and familial Alzheimer's disease mutants of APP and presenilin-1.
    Boutajangout A; Authelet M; Blanchard V; Touchet N; Tremp G; Pradier L; Brion JP
    Neurobiol Dis; 2004 Feb; 15(1):47-60. PubMed ID: 14751770
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.