145 related articles for article (PubMed ID: 30154106)
1. Evaluation of Organic Anion Transporter 1A2-knock-in Mice as a Model of Human Blood-brain Barrier.
Sano Y; Mizuno T; Mochizuki T; Uchida Y; Umetsu M; Terasaki T; Kusuhara H
Drug Metab Dispos; 2018 Nov; 46(11):1767-1775. PubMed ID: 30154106
[TBL] [Abstract][Full Text] [Related]
2. Solute Carrier Family of the Organic Anion-Transporting Polypeptides 1A2- Madin-Darby Canine Kidney II: A Promising In Vitro System to Understand the Role of Organic Anion-Transporting Polypeptide 1A2 in Blood-Brain Barrier Drug Penetration.
Liu H; Yu N; Lu S; Ito S; Zhang X; Prasad B; He E; Lu X; Li Y; Wang F; Xu H; An G; Unadkat JD; Kusuhara H; Sugiyama Y; Sahi J
Drug Metab Dispos; 2015 Jul; 43(7):1008-18. PubMed ID: 25908246
[TBL] [Abstract][Full Text] [Related]
3. Functional characterization of mouse organic anion transporting peptide 1a4 in the uptake and efflux of drugs across the blood-brain barrier.
Ose A; Kusuhara H; Endo C; Tohyama K; Miyajima M; Kitamura S; Sugiyama Y
Drug Metab Dispos; 2010 Jan; 38(1):168-76. PubMed ID: 19833843
[TBL] [Abstract][Full Text] [Related]
4. Hydrophilic anti-migraine triptans are substrates for OATP1A2, a transporter expressed at human blood-brain barrier.
Cheng Z; Liu H; Yu N; Wang F; An G; Xu Y; Liu Q; Guan CB; Ayrton A
Xenobiotica; 2012 Sep; 42(9):880-90. PubMed ID: 22509823
[TBL] [Abstract][Full Text] [Related]
5. Quantitative Determination of Luminal and Abluminal Membrane Distributions of Transporters in Porcine Brain Capillaries by Plasma Membrane Fractionation and Quantitative Targeted Proteomics.
Kubo Y; Ohtsuki S; Uchida Y; Terasaki T
J Pharm Sci; 2015 Sep; 104(9):3060-8. PubMed ID: 25703048
[TBL] [Abstract][Full Text] [Related]
6. Effects of β-blockers and tricyclic antidepressants on the activity of human organic anion transporting polypeptide 1A2 (OATP1A2).
Lu J; Michaud V; Moya LG; Gaudette F; Leung YH; Turgeon J
J Pharmacol Exp Ther; 2015 Mar; 352(3):552-8. PubMed ID: 25563901
[TBL] [Abstract][Full Text] [Related]
7. Sex-specific differences in organic anion transporting polypeptide 1a4 (Oatp1a4) functional expression at the blood-brain barrier in Sprague-Dawley rats.
Brzica H; Abdullahi W; Reilly BG; Ronaldson PT
Fluids Barriers CNS; 2018 Sep; 15(1):25. PubMed ID: 30208928
[TBL] [Abstract][Full Text] [Related]
8. Organic anion transporter 3 mediates the efflux transport of an amphipathic organic anion, dehydroepiandrosterone sulfate, across the blood-brain barrier in mice.
Miyajima M; Kusuhara H; Fujishima M; Adachi Y; Sugiyama Y
Drug Metab Dispos; 2011 May; 39(5):814-9. PubMed ID: 21325432
[TBL] [Abstract][Full Text] [Related]
9. Mouse reduced in osteosclerosis transporter functions as an organic anion transporter 3 and is localized at abluminal membrane of blood-brain barrier.
Ohtsuki S; Kikkawa T; Mori S; Hori S; Takanaga H; Otagiri M; Terasaki T
J Pharmacol Exp Ther; 2004 Jun; 309(3):1273-81. PubMed ID: 14762099
[TBL] [Abstract][Full Text] [Related]
10. Interindividual and Regional Variability in Drug Transporter Abundance at the Human Blood-Brain Barrier Measured by Quantitative Targeted Proteomics.
Billington S; Salphati L; Hop CECA; Chu X; Evers R; Burdette D; Rowbottom C; Lai Y; Xiao G; Humphreys WG; Nguyen TB; Prasad B; Unadkat JD
Clin Pharmacol Ther; 2019 Jul; 106(1):228-237. PubMed ID: 30673124
[TBL] [Abstract][Full Text] [Related]
11. Blood-brain barrier (BBB) pharmacoproteomics: reconstruction of in vivo brain distribution of 11 P-glycoprotein substrates based on the BBB transporter protein concentration, in vitro intrinsic transport activity, and unbound fraction in plasma and brain in mice.
Uchida Y; Ohtsuki S; Kamiie J; Terasaki T
J Pharmacol Exp Ther; 2011 Nov; 339(2):579-88. PubMed ID: 21828264
[TBL] [Abstract][Full Text] [Related]
12. Validation of a P-Glycoprotein (P-gp) Humanized Mouse Model by Integrating Selective Absolute Quantification of Human MDR1, Mouse Mdr1a and Mdr1b Protein Expressions with In Vivo Functional Analysis for Blood-Brain Barrier Transport.
Sadiq MW; Uchida Y; Hoshi Y; Tachikawa M; Terasaki T; Hammarlund-Udenaes M
PLoS One; 2015; 10(5):e0118638. PubMed ID: 25932627
[TBL] [Abstract][Full Text] [Related]
13. Quantitative targeted absolute proteomics of human blood-brain barrier transporters and receptors.
Uchida Y; Ohtsuki S; Katsukura Y; Ikeda C; Suzuki T; Kamiie J; Terasaki T
J Neurochem; 2011 Apr; 117(2):333-45. PubMed ID: 21291474
[TBL] [Abstract][Full Text] [Related]
14. Organic anion transporting polypeptide 1A2 mediates fentanyl uptake in cultured cells.
Huo XC; Yang HW; Huang LH; Zhang F; Pan ZY; Liao Q
Mol Med Rep; 2020 Jan; 21(1):485-492. PubMed ID: 31746415
[TBL] [Abstract][Full Text] [Related]
15. Influence of human OATP1B1, OATP1B3, and OATP1A2 on the pharmacokinetics of methotrexate and paclitaxel in humanized transgenic mice.
van de Steeg E; van Esch A; Wagenaar E; Kenworthy KE; Schinkel AH
Clin Cancer Res; 2013 Feb; 19(4):821-32. PubMed ID: 23243220
[TBL] [Abstract][Full Text] [Related]
16. Expression of the thyroid hormone transporters monocarboxylate transporter-8 (SLC16A2) and organic ion transporter-14 (SLCO1C1) at the blood-brain barrier.
Roberts LM; Woodford K; Zhou M; Black DS; Haggerty JE; Tate EH; Grindstaff KK; Mengesha W; Raman C; Zerangue N
Endocrinology; 2008 Dec; 149(12):6251-61. PubMed ID: 18687783
[TBL] [Abstract][Full Text] [Related]
17. Functional Expression of Organic Anion Transporting Polypeptide 1a4 Is Regulated by Transforming Growth Factor-
Abdullahi W; Brzica H; Hirsch NA; Reilly BG; Ronaldson PT
Mol Pharmacol; 2018 Dec; 94(6):1321-1333. PubMed ID: 30262595
[TBL] [Abstract][Full Text] [Related]
18. pH-dependent transport kinetics of the human organic anion-transporting polypeptide 1A2.
Morita T; Akiyoshi T; Sato R; Katayama K; Yajima K; Kataoka H; Imaoka A; Sugimoto Y; Ohtani H
Drug Metab Pharmacokinet; 2020 Apr; 35(2):220-227. PubMed ID: 31974044
[TBL] [Abstract][Full Text] [Related]
19. P-glycoprotein, breast cancer resistance protein, Organic Anion Transporter 3, and Transporting Peptide 1a4 during blood-brain barrier maturation: involvement of Wnt/β-catenin and endothelin-1 signaling.
Harati R; Benech H; Villégier AS; Mabondzo A
Mol Pharm; 2013 May; 10(5):1566-80. PubMed ID: 22998451
[TBL] [Abstract][Full Text] [Related]
20. OATP1A2 and OATP2B1 Are Interacting with Dopamine-Receptor Agonists and Antagonists.
Schäfer AM; Meyer Zu Schwabedissen HE; Bien-Möller S; Hubeny A; Vogelgesang S; Oswald S; Grube M
Mol Pharm; 2020 Jun; 17(6):1987-1995. PubMed ID: 32343897
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]