These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

135 related articles for article (PubMed ID: 30155826)

  • 1. Delivery of mtZFNs into Early Mouse Embryos.
    McCann BJ; Cox A; Gammage PA; Stewart JB; Zernicka-Goetz M; Minczuk M
    Methods Mol Biol; 2018; 1867():215-228. PubMed ID: 30155826
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Enhanced Manipulation of Human Mitochondrial DNA Heteroplasmy In Vitro Using Tunable mtZFN Technology.
    Gammage PA; Minczuk M
    Methods Mol Biol; 2018; 1867():43-56. PubMed ID: 30155814
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Manipulation of Murine Mitochondrial DNA Heteroplasmy with mtZFNs.
    Nash PA; Minczuk M
    Methods Mol Biol; 2023; 2615():329-344. PubMed ID: 36807802
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Genome editing in mitochondria corrects a pathogenic mtDNA mutation in vivo.
    Gammage PA; Viscomi C; Simard ML; Costa ASH; Gaude E; Powell CA; Van Haute L; McCann BJ; Rebelo-Guiomar P; Cerutti R; Zhang L; Rebar EJ; Zeviani M; Frezza C; Stewart JB; Minczuk M
    Nat Med; 2018 Nov; 24(11):1691-1695. PubMed ID: 30250142
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Near-complete elimination of mutant mtDNA by iterative or dynamic dose-controlled treatment with mtZFNs.
    Gammage PA; Gaude E; Van Haute L; Rebelo-Guiomar P; Jackson CB; Rorbach J; Pekalski ML; Robinson AJ; Charpentier M; Concordet JP; Frezza C; Minczuk M
    Nucleic Acids Res; 2016 Sep; 44(16):7804-16. PubMed ID: 27466392
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Manipulation of mitochondrial genes and mtDNA heteroplasmy.
    Bacman SR; Gammage PA; Minczuk M; Moraes CT
    Methods Cell Biol; 2020; 155():441-487. PubMed ID: 32183972
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Engineered mtZFNs for Manipulation of Human Mitochondrial DNA Heteroplasmy.
    Gammage PA; Van Haute L; Minczuk M
    Methods Mol Biol; 2016; 1351():145-62. PubMed ID: 26530680
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mitochondrially targeted ZFNs for selective degradation of pathogenic mitochondrial genomes bearing large-scale deletions or point mutations.
    Gammage PA; Rorbach J; Vincent AI; Rebar EJ; Minczuk M
    EMBO Mol Med; 2014 Apr; 6(4):458-66. PubMed ID: 24567072
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Mitochondrial DNA heteroplasmy in disease and targeted nuclease-based therapeutic approaches.
    Nissanka N; Moraes CT
    EMBO Rep; 2020 Mar; 21(3):e49612. PubMed ID: 32073748
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Selective elimination of mitochondrial mutations in the germline by genome editing.
    Reddy P; Ocampo A; Suzuki K; Luo J; Bacman SR; Williams SL; Sugawara A; Okamura D; Tsunekawa Y; Wu J; Lam D; Xiong X; Montserrat N; Esteban CR; Liu GH; Sancho-Martinez I; Manau D; Civico S; Cardellach F; Del Mar O'Callaghan M; Campistol J; Zhao H; Campistol JM; Moraes CT; Izpisua Belmonte JC
    Cell; 2015 Apr; 161(3):459-469. PubMed ID: 25910206
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Organ-specific shifts in mtDNA heteroplasmy following systemic delivery of a mitochondria-targeted restriction endonuclease.
    Bacman SR; Williams SL; Garcia S; Moraes CT
    Gene Ther; 2010 Jun; 17(6):713-20. PubMed ID: 20220783
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Targeted elimination of mutant mitochondrial DNA in MELAS-iPSCs by mitoTALENs.
    Yang Y; Wu H; Kang X; Liang Y; Lan T; Li T; Tan T; Peng J; Zhang Q; An G; Liu Y; Yu Q; Ma Z; Lian Y; Soh BS; Chen Q; Liu P; Chen Y; Sun X; Li R; Zhen X; Liu P; Yu Y; Li X; Fan Y
    Protein Cell; 2018 Mar; 9(3):283-297. PubMed ID: 29318513
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Therapeutic Manipulation of mtDNA Heteroplasmy: A Shifting Perspective.
    Jackson CB; Turnbull DM; Minczuk M; Gammage PA
    Trends Mol Med; 2020 Jul; 26(7):698-709. PubMed ID: 32589937
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A systematic analysis of the suitability of preimplantation genetic diagnosis for mitochondrial diseases in a heteroplasmic mitochondrial mouse model.
    Neupane J; Vandewoestyne M; Heindryckx B; Ghimire S; Lu Y; Qian C; Lierman S; Van Coster R; Gerris J; Deroo T; Deforce D; De Sutter P
    Hum Reprod; 2014 Apr; 29(4):852-9. PubMed ID: 24524987
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Metabolic rescue in pluripotent cells from patients with mtDNA disease.
    Ma H; Folmes CD; Wu J; Morey R; Mora-Castilla S; Ocampo A; Ma L; Poulton J; Wang X; Ahmed R; Kang E; Lee Y; Hayama T; Li Y; Van Dyken C; Gutierrez NM; Tippner-Hedges R; Koski A; Mitalipov N; Amato P; Wolf DP; Huang T; Terzic A; Laurent LC; Izpisua Belmonte JC; Mitalipov S
    Nature; 2015 Aug; 524(7564):234-8. PubMed ID: 26176921
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Anti-replicative recombinant 5S rRNA molecules can modulate the mtDNA heteroplasmy in a glucose-dependent manner.
    Loutre R; Heckel AM; Jeandard D; Tarassov I; Entelis N
    PLoS One; 2018; 13(6):e0199258. PubMed ID: 29912984
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Prospect of preimplantation genetic diagnosis for heritable mitochondrial DNA diseases.
    Dean NL; Battersby BJ; Ao A; Gosden RG; Tan SL; Shoubridge EA; Molnar MJ
    Mol Hum Reprod; 2003 Oct; 9(10):631-8. PubMed ID: 12970401
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Specific elimination of mutant mitochondrial genomes in patient-derived cells by mitoTALENs.
    Bacman SR; Williams SL; Pinto M; Peralta S; Moraes CT
    Nat Med; 2013 Sep; 19(9):1111-3. PubMed ID: 23913125
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Current strategies towards therapeutic manipulation of mtDNA heteroplasmy.
    Pereira CV; Moraes CT
    Front Biosci (Landmark Ed); 2017 Jan; 22(6):991-1010. PubMed ID: 27814659
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The mitochondrial genome in embryo technologies.
    Hiendleder S; Wolf E
    Reprod Domest Anim; 2003 Aug; 38(4):290-304. PubMed ID: 12887568
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.