BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

110 related articles for article (PubMed ID: 30165192)

  • 1. Smoothened stabilizes and protects TRAF6 from degradation: A novel non-canonical role of smoothened with implications in lymphoma biology.
    Qu C; Kunkalla K; Vaghefi A; Frederiksen JK; Liu Y; Chapman JR; Blonska M; Bernal-Mizrachi L; Alderuccio JP; Lossos IS; Landgraf R; Vega F
    Cancer Lett; 2018 Nov; 436():149-158. PubMed ID: 30165192
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Trimeric G protein-CARMA1 axis links smoothened, the hedgehog receptor transducer, to NF-κB activation in diffuse large B-cell lymphoma.
    Qu C; Liu Y; Kunkalla K; Singh RR; Blonska M; Lin X; Agarwal NK; Vega F
    Blood; 2013 Jun; 121(23):4718-28. PubMed ID: 23632891
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Smoothened (SMO) regulates insulin-like growth factor 1 receptor (IGF1R) levels and protein kinase B (AKT) localization and signaling.
    Agarwal NK; Kim CH; Kunkalla K; Vaghefi A; Sanchez S; Manuel S; Bilbao D; Vega F; Landgraf R
    Lab Invest; 2022 Apr; 102(4):401-410. PubMed ID: 34893758
    [TBL] [Abstract][Full Text] [Related]  

  • 4. ON 01910.Na inhibits growth of diffuse large B-cell lymphoma by cytoplasmic sequestration of sumoylated C-MYB/TRAF6 complex.
    Dai YH; Hung LY; Chen RY; Lai CH; Chang KC
    Transl Res; 2016 Sep; 175():129-143.e13. PubMed ID: 27150054
    [TBL] [Abstract][Full Text] [Related]  

  • 5. E3 ligase Herc4 regulates Hedgehog signalling through promoting Smoothened degradation.
    Jiang W; Yao X; Shan Z; Li W; Gao Y; Zhang Q
    J Mol Cell Biol; 2019 Sep; 11(9):791-803. PubMed ID: 30925584
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Tumor necrosis factor receptor-associated factor 6 contributes to malignant behavior of human cancers through promoting AKT ubiquitination and phosphorylation.
    Shi J; Liu Z; Xu Q
    Cancer Sci; 2019 Jun; 110(6):1909-1920. PubMed ID: 30945383
    [TBL] [Abstract][Full Text] [Related]  

  • 7. TRAF6 interacts with and ubiquitinates PIK3CA to enhance PI3K activation.
    Wang Z; Liu Y; Huang S; Fang M
    FEBS Lett; 2018 Jun; 592(11):1882-1892. PubMed ID: 29729098
    [TBL] [Abstract][Full Text] [Related]  

  • 8. TRAF6 is functional in inhibition of TLR4-mediated NF-κB activation by resveratrol.
    Jakus PB; Kalman N; Antus C; Radnai B; Tucsek Z; Gallyas F; Sumegi B; Veres B
    J Nutr Biochem; 2013 May; 24(5):819-23. PubMed ID: 22925919
    [TBL] [Abstract][Full Text] [Related]  

  • 9. SUMO regulates the activity of Smoothened and Costal-2 in Drosophila Hedgehog signaling.
    Zhang J; Liu Y; Jiang K; Jia J
    Sci Rep; 2017 Feb; 7():42749. PubMed ID: 28195188
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Defining causative factors contributing in the activation of hedgehog signaling in diffuse large B-cell lymphoma.
    Ramirez E; Singh RR; Kunkalla K; Liu Y; Qu C; Cain C; Multani AS; Lennon PA; Jackacky J; Ho M; Dawud S; Gu J; Yang S; Hu PC; Vega F
    Leuk Res; 2012 Oct; 36(10):1267-73. PubMed ID: 22809693
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Fbw7 regulates apoptosis in activated B-cell like diffuse large B-cell lymphoma by targeting Stat3 for ubiquitylation and degradation.
    Yao S; Xu F; Chen Y; Ge Y; Zhang F; Huang H; Li L; Lin D; Luo X; Xu J; Luo D; Zhu X; Liu Y
    J Exp Clin Cancer Res; 2017 Jan; 36(1):10. PubMed ID: 28069035
    [TBL] [Abstract][Full Text] [Related]  

  • 12. MicroRNA-21 plays an oncogenic role by targeting FOXO1 and activating the PI3K/AKT pathway in diffuse large B-cell lymphoma.
    Go H; Jang JY; Kim PJ; Kim YG; Nam SJ; Paik JH; Kim TM; Heo DS; Kim CW; Jeon YK
    Oncotarget; 2015 Jun; 6(17):15035-49. PubMed ID: 25909227
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Overcoming the emerging drug resistance of smoothened: an overview of small-molecule SMO antagonists with antiresistance activity.
    Zhang H; Sun Z; Liu Z; Song C
    Future Med Chem; 2018 Dec; 10(24):2855-2875. PubMed ID: 30557039
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Akt, 14-3-3ζ, and vimentin mediate a drug-resistant invasive phenotype in diffuse large B-cell lymphoma.
    Maxwell SA; Cherry EM; Bayless KJ
    Leuk Lymphoma; 2011 May; 52(5):849-64. PubMed ID: 21323512
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Regulation of Smoothened Phosphorylation and High-Level Hedgehog Signaling Activity by a Plasma Membrane Associated Kinase.
    Li S; Li S; Han Y; Tong C; Wang B; Chen Y; Jiang J
    PLoS Biol; 2016 Jun; 14(6):e1002481. PubMed ID: 27280464
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Epigallocatechin-3-gallate(EGCG) suppresses melanoma cell growth and metastasis by targeting TRAF6 activity.
    Zhang J; Lei Z; Huang Z; Zhang X; Zhou Y; Luo Z; Zeng W; Su J; Peng C; Chen X
    Oncotarget; 2016 Nov; 7(48):79557-79571. PubMed ID: 27791197
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Activation of the PI3K/AKT/mTOR pathway in diffuse large B cell lymphoma: clinical significance and inhibitory effect of rituximab.
    Xu ZZ; Xia ZG; Wang AH; Wang WF; Liu ZY; Chen LY; Li JM
    Ann Hematol; 2013 Oct; 92(10):1351-8. PubMed ID: 23636313
    [TBL] [Abstract][Full Text] [Related]  

  • 18. SMO Gene Amplification and Activation of the Hedgehog Pathway as Novel Mechanisms of Resistance to Anti-Epidermal Growth Factor Receptor Drugs in Human Lung Cancer.
    Della Corte CM; Bellevicine C; Vicidomini G; Vitagliano D; Malapelle U; Accardo M; Fabozzi A; Fiorelli A; Fasano M; Papaccio F; Martinelli E; Troiani T; Troncone G; Santini M; Bianco R; Ciardiello F; Morgillo F
    Clin Cancer Res; 2015 Oct; 21(20):4686-97. PubMed ID: 26124204
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Hedgehog signaling pathway is activated in diffuse large B-cell lymphoma and contributes to tumor cell survival and proliferation.
    Singh RR; Kim JE; Davuluri Y; Drakos E; Cho-Vega JH; Amin HM; Vega F
    Leukemia; 2010 May; 24(5):1025-36. PubMed ID: 20200556
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Presenilins are novel substrates for TRAF6-mediated ubiquitination.
    Yan R; Farrelly S; McCarthy JV
    Cell Signal; 2013 Sep; 25(9):1769-79. PubMed ID: 23707529
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.