BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

204 related articles for article (PubMed ID: 30168823)

  • 21. The structural requirements of histone deacetylase inhibitors: C4-modified SAHA analogs display dual HDAC6/HDAC8 selectivity.
    Negmeldin AT; Knoff JR; Pflum MKH
    Eur J Med Chem; 2018 Jan; 143():1790-1806. PubMed ID: 29150330
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Investigation of non-hydroxamate scaffolds against HDAC6 inhibition: A pharmacophore modeling, molecular docking, and molecular dynamics simulation approach.
    Zeb A; Park C; Son M; Rampogu S; Alam SI; Park SJ; Lee KW
    J Bioinform Comput Biol; 2018 Jun; 16(3):1840015. PubMed ID: 29945500
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Design, Synthesis and Biological Evaluation of a Phenyl Butyric Acid Derivative, N-(4-chlorophenyl)-4-phenylbutanamide: A HDAC6 Inhibitor with Anti-proliferative Activity on Cervix Cancer and Leukemia Cells.
    Rodríguez-Fonseca RA; Sixto-López Y; Fragoso-Vázquez MJ; Flores-Mejía R; Cabrera-Pérez LC; Vázquez-Moctezuma I; Rosales-Hernández MC; Bello M; Martínez-Archundia M; Trujillo-Ferrara JG; Becerra-Martínez E; Correa-Basurto J
    Anticancer Agents Med Chem; 2017; 17(10):1441-1454. PubMed ID: 28044941
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Structure, Functions and Selective Inhibitors of HDAC6.
    Liang T; Fang H
    Curr Top Med Chem; 2018; 18(28):2429-2447. PubMed ID: 30499393
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Novel 2, 5-diketopiperazine derivatives as potent selective histone deacetylase 6 inhibitors: Rational design, synthesis and antiproliferative activity.
    Chen X; Chen X; Steimbach RR; Wu T; Li H; Dan W; Shi P; Cao C; Li D; Miller AK; Qiu Z; Gao J; Zhu Y
    Eur J Med Chem; 2020 Feb; 187():111950. PubMed ID: 31865013
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Discovery of Novel Histone Deacetylase 6 (HDAC6) Inhibitors with Enhanced Antitumor Immunity of Anti-PD-L1 Immunotherapy in Melanoma.
    Peng X; Li L; Chen J; Ren Y; Liu J; Yu Z; Cao H; Chen J
    J Med Chem; 2022 Feb; 65(3):2434-2457. PubMed ID: 35043615
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Structure-activity relationship study of thiazolyl-hydroxamate derivatives as selective histone deacetylase 6 inhibitors.
    Nam G; Jung JM; Park HJ; Baek SY; Baek KS; Mok HY; Kim DE; Jung YH
    Bioorg Med Chem; 2019 Aug; 27(15):3408-3420. PubMed ID: 31235266
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Design, synthesis and biological evaluation of selective histone deacetylase 6 (HDAC6) inhibitors bearing benzoindazole or pyrazoloindazole scaffold as surface recognition motif.
    Xu Q; Mou Y; Wang S; Gao X; Zhang Y; Wang Z; Xu X; Han Y; Jia W; Zhang M; Zhao L; Liu D
    Bioorg Chem; 2021 Jun; 111():104910. PubMed ID: 33894432
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Identification of Novel Histone Deacetylase 6-Selective Inhibitors Bearing 3,3,3-Trifluorolactic Amide (TFLAM) Motif as a Zinc Binding Group.
    Kurohara T; Tanaka K; Takahashi D; Ueda S; Yamashita Y; Takada Y; Takeshima H; Yu S; Itoh Y; Hase K; Suzuki T
    Chembiochem; 2021 Nov; 22(22):3158-3163. PubMed ID: 34224197
    [TBL] [Abstract][Full Text] [Related]  

  • 30. HDAC6 inhibition protects cardiomyocytes against doxorubicin-induced acute damage by improving α-tubulin acetylation.
    Song R; Yang Y; Lei H; Wang G; Huang Y; Xue W; Wang Y; Yao L; Zhu Y
    J Mol Cell Cardiol; 2018 Nov; 124():58-69. PubMed ID: 30315806
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Structure-Based Drug Designing Recommends HDAC6 Inhibitors To Attenuate Microtubule-Associated Tau-Pathogenesis.
    Zeb A; Park C; Rampogu S; Son M; Lee G; Lee KW
    ACS Chem Neurosci; 2019 Mar; 10(3):1326-1335. PubMed ID: 30407786
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Quinazolin-2,4-dione-Based Hydroxamic Acids as Selective Histone Deacetylase-6 Inhibitors for Treatment of Non-Small Cell Lung Cancer.
    Yu CW; Hung PY; Yang HT; Ho YH; Lai HY; Cheng YS; Chern JW
    J Med Chem; 2019 Jan; 62(2):857-874. PubMed ID: 30525585
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Unusual zinc-binding mode of HDAC6-selective hydroxamate inhibitors.
    Porter NJ; Mahendran A; Breslow R; Christianson DW
    Proc Natl Acad Sci U S A; 2017 Dec; 114(51):13459-13464. PubMed ID: 29203661
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Novel quinolone-based potent and selective HDAC6 inhibitors: Synthesis, molecular modeling studies and biological investigation.
    Relitti N; Saraswati AP; Chemi G; Brindisi M; Brogi S; Herp D; Schmidtkunz K; Saccoccia F; Ruberti G; Ulivieri C; Vanni F; Sarno F; Altucci L; Lamponi S; Jung M; Gemma S; Butini S; Campiani G
    Eur J Med Chem; 2021 Feb; 212():112998. PubMed ID: 33199154
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Inhibitors of histone deacetylase 6 based on a novel 3-hydroxy-isoxazole zinc binding group.
    Linciano P; Pinzi L; Belluti S; Chianese U; Benedetti R; Moi D; Altucci L; Franchini S; Imbriano C; Sorbi C; Rastelli G
    J Enzyme Inhib Med Chem; 2021 Dec; 36(1):2080-2086. PubMed ID: 34583596
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Fluorescence Polarization-Based Competition Assays to Evaluate Histone Deacetylase 6 Inhibitors.
    Ashraf QF; Quilates EJ; Olaoye OO; de Araujo ED; Gunning PT
    Methods Mol Biol; 2023; 2589():481-492. PubMed ID: 36255644
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Synthesis and structure-activity relationship of thiol-based histone deacetylase 6 inhibitors.
    Guo Z; Zhang Y; Bao Y; Huang Z; Gu X; Wang G; Li J
    Chem Biol Drug Des; 2022 Jul; 100(1):90-107. PubMed ID: 35404520
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Molecular docking-based virtual drug screening revealing an oxofluorenyl benzamide and a bromonaphthalene sulfonamido hydroxybenzoic acid as HDAC6 inhibitors with cytotoxicity against leukemia cells.
    Dawood M; Elbadawi M; Böckers M; Bringmann G; Efferth T
    Biomed Pharmacother; 2020 Sep; 129():110454. PubMed ID: 32768947
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Selective pharmacological inhibitors of HDAC6 reveal biochemical activity but functional tolerance in cancer models.
    Depetter Y; Geurs S; De Vreese R; Goethals S; Vandoorn E; Laevens A; Steenbrugge J; Meyer E; de Tullio P; Bracke M; D'hooghe M; De Wever O
    Int J Cancer; 2019 Aug; 145(3):735-747. PubMed ID: 30694564
    [TBL] [Abstract][Full Text] [Related]  

  • 40. High-selective HDAC6 inhibitor promotes HDAC6 degradation following autophagy modulation and enhanced antitumor immunity in glioblastoma.
    Liu JR; Yu CW; Hung PY; Hsin LW; Chern JW
    Biochem Pharmacol; 2019 May; 163():458-471. PubMed ID: 30885763
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 11.