223 related articles for article (PubMed ID: 30177851)
1. A novel cell-based screening assay for small-molecule MYB inhibitors identifies podophyllotoxins teniposide and etoposide as inhibitors of MYB activity.
Yusenko M; Jakobs A; Klempnauer KH
Sci Rep; 2018 Sep; 8(1):13159. PubMed ID: 30177851
[TBL] [Abstract][Full Text] [Related]
2. Targeting the transcription factor Myb by small-molecule inhibitors.
Uttarkar S; Frampton J; Klempnauer KH
Exp Hematol; 2017 Mar; 47():31-35. PubMed ID: 28017646
[TBL] [Abstract][Full Text] [Related]
3. Discovery of podophyllotoxins.
Imbert TF
Biochimie; 1998 Mar; 80(3):207-22. PubMed ID: 9615861
[TBL] [Abstract][Full Text] [Related]
4. The natural anti-tumor compound Celastrol targets a Myb-C/EBPβ-p300 transcriptional module implicated in myeloid gene expression.
Coulibaly A; Haas A; Steinmann S; Jakobs A; Schmidt TJ; Klempnauer KH
PLoS One; 2018; 13(2):e0190934. PubMed ID: 29394256
[TBL] [Abstract][Full Text] [Related]
5. Recent advances in semisynthesis, biosynthesis, biological activities, mode of action, and structure-activity relationship of podophyllotoxins: an update (2008-2010).
Lv M; Xu H
Mini Rev Med Chem; 2011 Sep; 11(10):901-9. PubMed ID: 21781026
[TBL] [Abstract][Full Text] [Related]
6. Antitumor properties of podophyllotoxin and related compounds.
Gordaliza M; Castro MA; del Corral JM; Feliciano AS
Curr Pharm Des; 2000 Dec; 6(18):1811-39. PubMed ID: 11102564
[TBL] [Abstract][Full Text] [Related]
7. A review on hemisynthesis, biosynthesis, biological activities, mode of action, and structure-activity relationship of podophyllotoxins: 2003-2007.
Xu H; Lv M; Tian X
Curr Med Chem; 2009; 16(3):327-49. PubMed ID: 19149581
[TBL] [Abstract][Full Text] [Related]
8. Targeting acute myeloid leukemia with a small molecule inhibitor of the Myb/p300 interaction.
Uttarkar S; Dassé E; Coulibaly A; Steinmann S; Jakobs A; Schomburg C; Trentmann A; Jose J; Schlenke P; Berdel WE; Schmidt TJ; Müller-Tidow C; Frampton J; Klempnauer KH
Blood; 2016 Mar; 127(9):1173-82. PubMed ID: 26631113
[TBL] [Abstract][Full Text] [Related]
9. Small-Molecule Disruption of the Myb/p300 Cooperation Targets Acute Myeloid Leukemia Cells.
Uttarkar S; Piontek T; Dukare S; Schomburg C; Schlenke P; Berdel WE; Müller-Tidow C; Schmidt TJ; Klempnauer KH
Mol Cancer Ther; 2016 Dec; 15(12):2905-2915. PubMed ID: 27707899
[TBL] [Abstract][Full Text] [Related]
10. DNA topoisomerase II inhibitors induce macrophage ABCA1 expression and cholesterol efflux-an LXR-dependent mechanism.
Zhang L; Jiang M; Shui Y; Chen Y; Wang Q; Hu W; Ma X; Li X; Liu X; Cao X; Liu M; Duan Y; Han J
Biochim Biophys Acta; 2013 Jun; 1831(6):1134-45. PubMed ID: 23466610
[TBL] [Abstract][Full Text] [Related]
11. [In vitro comparison of podophyllotoxin analogues; etoposide, teniposide and NK 611 using human lung cancer cell lines].
Takigawa N; Ohnoshi T; Ueoka H; Kiura K; Moritaka T; Tabata M; Segawa Y; Shibayama T; Gemba K; Matsumura T
Gan To Kagaku Ryoho; 1993 Mar; 20(4):473-7. PubMed ID: 8383949
[TBL] [Abstract][Full Text] [Related]
12. Mechanisms of action of teniposide (VM-26) and comparison with etoposide (VP-16).
Long BH
Semin Oncol; 1992 Apr; 19(2 Suppl 6):3-19. PubMed ID: 1329225
[TBL] [Abstract][Full Text] [Related]
13. Evidence that the apoptotic actions of etoposide are independent of c-Jun/activating protein-1-mediated transregulation.
Jarvis WD; Johnson CR; Fornari FA; Park JS; Dent P; Grant S
J Pharmacol Exp Ther; 1999 Sep; 290(3):1384-92. PubMed ID: 10454518
[TBL] [Abstract][Full Text] [Related]
14. Altered formation of DNA in human cells treated with inhibitors of DNA topoisomerase II (etoposide and teniposide).
Lönn U; Lönn S; Nylen U; Winblad G
Cancer Res; 1989 Nov; 49(22):6202-7. PubMed ID: 2553248
[TBL] [Abstract][Full Text] [Related]
15. Naphthol AS-E Phosphate Inhibits the Activity of the Transcription Factor Myb by Blocking the Interaction with the KIX Domain of the Coactivator p300.
Uttarkar S; Dukare S; Bopp B; Goblirsch M; Jose J; Klempnauer KH
Mol Cancer Ther; 2015 Jun; 14(6):1276-85. PubMed ID: 25740244
[TBL] [Abstract][Full Text] [Related]
16. DNA damage signals induction of fas ligand in tumor cells.
Mo YY; Beck WT
Mol Pharmacol; 1999 Feb; 55(2):216-22. PubMed ID: 9927611
[TBL] [Abstract][Full Text] [Related]
17. The effect of the two epipodophyllotoxin derivatives etoposide (VP-16) and teniposide (VM-26) on cell lines established from patients with small cell carcinoma of the lung.
Roed H; Vindelov LL; Christensen IJ; Spang-Thomsen M; Hansen HH
Cancer Chemother Pharmacol; 1987; 19(1):16-20. PubMed ID: 3815721
[TBL] [Abstract][Full Text] [Related]
18. DNA breakage in human lung carcinoma cells and nuclei that are naturally sensitive or resistant to etoposide and teniposide.
Long BH; Musial ST; Brattain MG
Cancer Res; 1986 Aug; 46(8):3809-16. PubMed ID: 3015377
[TBL] [Abstract][Full Text] [Related]
19. Protein-linked DNA strand breaks produced by etoposide and teniposide in mouse L1210 and human VA-13 and HT-29 cell lines: relationship to cytotoxicity.
Kerrigan D; Pommier Y; Kohn KW
NCI Monogr; 1987; (4):117-21. PubMed ID: 3041238
[TBL] [Abstract][Full Text] [Related]
20. Etoposide and teniposide in the treatment of acute leukemia.
Björkholm M
Med Oncol Tumor Pharmacother; 1990; 7(1):3-10. PubMed ID: 2187120
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]