105 related articles for article (PubMed ID: 30182300)
1. Thymocyte self-renewal and oncogenic risk in immunodeficient mouse models: relevance for human gene therapy clinical trials targeting haematopoietic stem cell populations?
Ginn SL; McCormack MP; Alexander IE
Mamm Genome; 2018 Dec; 29(11-12):771-776. PubMed ID: 30182300
[TBL] [Abstract][Full Text] [Related]
2. Ldb1 is required for Lmo2 oncogene-induced thymocyte self-renewal and T-cell acute lymphoblastic leukemia.
Li L; Mitra A; Cui K; Zhao B; Choi S; Lee JY; Stamos DB; El-Khoury D; Warzecha C; Pfeifer K; Hardwick J; Zhao K; Venters B; Davé UP; Love PE
Blood; 2020 Jun; 135(25):2252-2265. PubMed ID: 32181817
[TBL] [Abstract][Full Text] [Related]
3. Limiting Thymic Precursor Supply Increases the Risk of Lymphoid Malignancy in Murine X-Linked Severe Combined Immunodeficiency.
Ginn SL; Hallwirth CV; Liao SHY; Teber ET; Arthur JW; Wu J; Lee HC; Tay SS; Hu M; Reddel RR; McCormack MP; Thrasher AJ; Cavazzana M; Alexander SI; Alexander IE
Mol Ther Nucleic Acids; 2017 Mar; 6():1-14. PubMed ID: 28325276
[TBL] [Abstract][Full Text] [Related]
4. SCL, LMO1 and Notch1 reprogram thymocytes into self-renewing cells.
Gerby B; Tremblay CS; Tremblay M; Rojas-Sutterlin S; Herblot S; Hébert J; Sauvageau G; Lemieux S; Lécuyer E; Veiga DF; Hoang T
PLoS Genet; 2014 Dec; 10(12):e1004768. PubMed ID: 25522233
[TBL] [Abstract][Full Text] [Related]
5. Hhex regulates Kit to promote radioresistance of self-renewing thymocytes in Lmo2-transgenic mice.
Shields BJ; Alserihi R; Nasa C; Bogue C; Alexander WS; McCormack MP
Leukemia; 2015 Apr; 29(4):927-38. PubMed ID: 25283843
[TBL] [Abstract][Full Text] [Related]
6. Overexpression of Lmo2 initiates T-lymphoblastic leukemia via impaired thymocyte competition.
Abdulla HD; Alserihi R; Flensburg C; Abeysekera W; Luo MX; Gray DHD; Liu X; Smyth GK; Alexander WS; Majewski IJ; McCormack MP
J Exp Med; 2023 Jun; 220(6):. PubMed ID: 36920307
[TBL] [Abstract][Full Text] [Related]
7. Evaluating the Safety of Retroviral Vectors Based on Insertional Oncogene Activation and Blocked Differentiation in Cultured Thymocytes.
Zhou S; Fatima S; Ma Z; Wang YD; Lu T; Janke LJ; Du Y; Sorrentino BP
Mol Ther; 2016 Jun; 24(6):1090-1099. PubMed ID: 26957223
[TBL] [Abstract][Full Text] [Related]
8. ZEB2 and LMO2 drive immature T-cell lymphoblastic leukemia via distinct oncogenic mechanisms.
Goossens S; Wang J; Tremblay CS; De Medts J; T'Sas S; Nguyen T; Saw J; Haigh K; Curtis DJ; Van Vlierberghe P; Berx G; Taghon T; Haigh JJ
Haematologica; 2019 Aug; 104(8):1608-1616. PubMed ID: 30679322
[TBL] [Abstract][Full Text] [Related]
9. LMO2 and IL2RG synergize in thymocytes to mimic the evolution of SCID-X1 gene therapy-associated T-cell leukaemia.
Ruggero K; Al-Assar O; Chambers JS; Codrington R; Brend T; Rabbitts TH
Leukemia; 2016 Sep; 30(9):1959-62. PubMed ID: 27256700
[No Abstract] [Full Text] [Related]
10. Lmo2 expression defines tumor cell identity during T-cell leukemogenesis.
García-Ramírez I; Bhatia S; Rodríguez-Hernández G; González-Herrero I; Walter C; González de Tena-Dávila S; Parvin S; Haas O; Woessmann W; Stanulla M; Schrappe M; Dugas M; Natkunam Y; Orfao A; Domínguez V; Pintado B; Blanco O; Alonso-López D; De Las Rivas J; Martín-Lorenzo A; Jiménez R; García Criado FJ; García Cenador MB; Lossos IS; Vicente-Dueñas C; Borkhardt A; Hauer J; Sánchez-García I
EMBO J; 2018 Jul; 37(14):. PubMed ID: 29880602
[TBL] [Abstract][Full Text] [Related]
11. The LMO2 oncogene regulates DNA replication in hematopoietic cells.
Sincennes MC; Humbert M; Grondin B; Lisi V; Veiga DF; Haman A; Cazaux C; Mashtalir N; Affar el B; Verreault A; Hoang T
Proc Natl Acad Sci U S A; 2016 Feb; 113(5):1393-8. PubMed ID: 26764384
[TBL] [Abstract][Full Text] [Related]
12. The LIM-only transcription factor LMO2 determines tumorigenic and angiogenic traits in glioma stem cells.
Kim SH; Kim EJ; Hitomi M; Oh SY; Jin X; Jeon HM; Beck S; Jin X; Kim JK; Park CG; Chang SY; Yin J; Kim T; Jeon YJ; Song J; Lim YC; Lathia JD; Nakano I; Kim H
Cell Death Differ; 2015 Sep; 22(9):1517-25. PubMed ID: 25721045
[TBL] [Abstract][Full Text] [Related]
13. Foamy Virus Vector Carries a Strong Insulator in Its Long Terminal Repeat Which Reduces Its Genotoxic Potential.
Goodman MA; Arumugam P; Pillis DM; Loberg A; Nasimuzzaman M; Lynn D; van der Loo JCM; Dexheimer PJ; Keddache M; Bauer TR; Hickstein DD; Russell DW; Malik P
J Virol; 2018 Jan; 92(1):. PubMed ID: 29046446
[TBL] [Abstract][Full Text] [Related]
14. Lmo2 induces hematopoietic stem cell-like features in T-cell progenitor cells prior to leukemia.
Cleveland SM; Smith S; Tripathi R; Mathias EM; Goodings C; Elliott N; Peng D; El-Rifai W; Yi D; Chen X; Li L; Mullighan C; Downing JR; Love P; Davé UP
Stem Cells; 2013 May; 31(5):882-94. PubMed ID: 23378057
[TBL] [Abstract][Full Text] [Related]
15. LMO2 attenuates tumor growth by targeting the Wnt signaling pathway in breast and colorectal cancer.
Liu Y; Huang D; Wang Z; Wu C; Zhang Z; Wang D; Li Z; Zhu T; Yang S; Sun W
Sci Rep; 2016 Oct; 6():36050. PubMed ID: 27779255
[TBL] [Abstract][Full Text] [Related]
16. Ectopic retroviral expression of LMO2, but not IL2Rgamma, blocks human T-cell development from CD34+ cells: implications for leukemogenesis in gene therapy.
Pike-Overzet K; de Ridder D; Weerkamp F; Baert MR; Verstegen MM; Brugman MH; Howe SJ; Reinders MJ; Thrasher AJ; Wagemaker G; van Dongen JJ; Staal FJ
Leukemia; 2007 Apr; 21(4):754-63. PubMed ID: 17268520
[TBL] [Abstract][Full Text] [Related]
17. Concise review: managing genotoxicity in the therapeutic modification of stem cells.
Baum C; Modlich U; Göhring G; Schlegelberger B
Stem Cells; 2011 Oct; 29(10):1479-84. PubMed ID: 21898683
[TBL] [Abstract][Full Text] [Related]
18. Enhanced self-renewal capability in hepatic stem/progenitor cells drives cancer initiation.
Chiba T; Zheng YW; Kita K; Yokosuka O; Saisho H; Onodera M; Miyoshi H; Nakano M; Zen Y; Nakanuma Y; Nakauchi H; Iwama A; Taniguchi H
Gastroenterology; 2007 Sep; 133(3):937-50. PubMed ID: 17673212
[TBL] [Abstract][Full Text] [Related]
19. Enforced expression of E47 has differential effects on Lmo2-induced T-cell leukemias.
Goodings C; Tripathi R; Cleveland SM; Elliott N; Guo Y; Shyr Y; Davé UP
Leuk Res; 2015 Jan; 39(1):100-9. PubMed ID: 25499232
[TBL] [Abstract][Full Text] [Related]
20. SCL/TAL1 in Hematopoiesis and Cellular Reprogramming.
Hoang T; Lambert JA; Martin R
Curr Top Dev Biol; 2016; 118():163-204. PubMed ID: 27137657
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]