BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

169 related articles for article (PubMed ID: 30195075)

  • 1. Motor neuron loss and neuroinflammation in a model of α-synuclein-induced neurodegeneration.
    Sorrentino ZA; Xia Y; Funk C; Riffe CJ; Rutherford NJ; Ceballos Diaz C; Sacino AN; Price ND; Golde TE; Giasson BI; Chakrabarty P
    Neurobiol Dis; 2018 Dec; 120():98-106. PubMed ID: 30195075
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Intrastriatal injection of α-synuclein can lead to widespread synucleinopathy independent of neuroanatomic connectivity.
    Sorrentino ZA; Brooks MMT; Hudson V; Rutherford NJ; Golde TE; Giasson BI; Chakrabarty P
    Mol Neurodegener; 2017 May; 12(1):40. PubMed ID: 28552073
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Intramuscular injection of α-synuclein induces CNS α-synuclein pathology and a rapid-onset motor phenotype in transgenic mice.
    Sacino AN; Brooks M; Thomas MA; McKinney AB; Lee S; Regenhardt RW; McGarvey NH; Ayers JI; Notterpek L; Borchelt DR; Golde TE; Giasson BI
    Proc Natl Acad Sci U S A; 2014 Jul; 111(29):10732-7. PubMed ID: 25002524
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Peripheral Inflammation Regulates CNS Immune Surveillance Through the Recruitment of Inflammatory Monocytes Upon Systemic α-Synuclein Administration.
    Peralta Ramos JM; Iribarren P; Bousset L; Melki R; Baekelandt V; Van der Perren A
    Front Immunol; 2019; 10():80. PubMed ID: 30761145
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Carboxy-terminal truncation and phosphorylation of α-synuclein elongates survival in a prion-like seeding mouse model of synucleinopathy.
    Sorrentino ZA; Hass E; Vijayaraghavan N; Gorion KM; Riffe CJ; Dhillon JS; Giasson BI
    Neurosci Lett; 2020 Jul; 732():135017. PubMed ID: 32371157
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Gamma-synucleinopathy: neurodegeneration associated with overexpression of the mouse protein.
    Ninkina N; Peters O; Millership S; Salem H; van der Putten H; Buchman VL
    Hum Mol Genet; 2009 May; 18(10):1779-94. PubMed ID: 19246516
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Loss of spinal motor neurons and alteration of alpha-synuclein immunostaining in MPTP induced Parkinsonism in mice.
    Vivacqua G; Biagioni F; Yu S; Casini A; Bucci D; D'Este L; Fornai F
    J Chem Neuroanat; 2012 Jul; 44(2):76-85. PubMed ID: 22580273
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Inflammatory pre-conditioning restricts the seeded induction of α-synuclein pathology in wild type mice.
    Koller EJ; Brooks MM; Golde TE; Giasson BI; Chakrabarty P
    Mol Neurodegener; 2017 Jan; 12(1):1. PubMed ID: 28049533
    [TBL] [Abstract][Full Text] [Related]  

  • 9. High expression of α-synuclein in damaged mitochondria with PLA2G6 dysfunction.
    Sumi-Akamaru H; Beck G; Shinzawa K; Kato S; Riku Y; Yoshida M; Fujimura H; Tsujimoto Y; Sakoda S; Mochizuki H
    Acta Neuropathol Commun; 2016 Mar; 4():27. PubMed ID: 27030050
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The MHC class II transactivator modulates seeded alpha-synuclein pathology and dopaminergic neurodegeneration in an in vivo rat model of Parkinson's disease.
    Jimenez-Ferrer I; Bäckström F; Dueñas-Rey A; Jewett M; Boza-Serrano A; Luk KC; Deierborg T; Swanberg M
    Brain Behav Immun; 2021 Jan; 91():369-382. PubMed ID: 33223048
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Endothelial LRP1-ICD Accelerates Cognition-Associated Alpha-Synuclein Pathology and Neurodegeneration through PARP1 Activation in a Mouse Model of Parkinson's Disease.
    Huang R; Gao Y; Duan Q; Zhang Q; He P; Chen J; Ma G; Wang L; Zhang Y; Nie K; Wang L
    Mol Neurobiol; 2023 Feb; 60(2):979-1003. PubMed ID: 36394710
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Robust Central Nervous System Pathology in Transgenic Mice following Peripheral Injection of α-Synuclein Fibrils.
    Ayers JI; Brooks MM; Rutherford NJ; Howard JK; Sorrentino ZA; Riffe CJ; Giasson BI
    J Virol; 2017 Jan; 91(2):. PubMed ID: 27852849
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Neuronal alpha-synucleinopathy with severe movement disorder in mice expressing A53T human alpha-synuclein.
    Giasson BI; Duda JE; Quinn SM; Zhang B; Trojanowski JQ; Lee VM
    Neuron; 2002 May; 34(4):521-33. PubMed ID: 12062037
    [TBL] [Abstract][Full Text] [Related]  

  • 14. rAAV2/7 vector-mediated overexpression of alpha-synuclein in mouse substantia nigra induces protein aggregation and progressive dose-dependent neurodegeneration.
    Oliveras-Salvá M; Van der Perren A; Casadei N; Stroobants S; Nuber S; D'Hooge R; Van den Haute C; Baekelandt V
    Mol Neurodegener; 2013 Nov; 8():44. PubMed ID: 24267638
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Parkinson's disease alpha-synuclein transgenic mice develop neuronal mitochondrial degeneration and cell death.
    Martin LJ; Pan Y; Price AC; Sterling W; Copeland NG; Jenkins NA; Price DL; Lee MK
    J Neurosci; 2006 Jan; 26(1):41-50. PubMed ID: 16399671
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Systemic proteasome inhibition triggers neurodegeneration in a transgenic mouse model expressing human α-synuclein under oligodendrocyte promoter: implications for multiple system atrophy.
    Stefanova N; Kaufmann WA; Humpel C; Poewe W; Wenning GK
    Acta Neuropathol; 2012 Jul; 124(1):51-65. PubMed ID: 22491959
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Rab7 reduces α-synuclein toxicity in rats and primary neurons.
    Szegö EM; Van den Haute C; Höfs L; Baekelandt V; Van der Perren A; Falkenburger BH
    Exp Neurol; 2022 Jan; 347():113900. PubMed ID: 34695425
    [TBL] [Abstract][Full Text] [Related]  

  • 18. High-salt diet does not boost neuroinflammation and neurodegeneration in a model of α-synucleinopathy.
    Heras-Garvin A; Refolo V; Reindl M; Wenning GK; Stefanova N
    J Neuroinflammation; 2020 Jan; 17(1):35. PubMed ID: 31980040
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Minocycline inhibition of microglial rescues nigrostriatal dopaminergic neurodegeneration caused by mutant alpha-synuclein overexpression.
    Wang Y; Wang Q; Yu R; Zhang Q; Zhang Z; Li H; Ren C; Yang R; Niu H
    Aging (Albany NY); 2020 Jul; 12(14):14232-14243. PubMed ID: 32706757
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Pesticide exposure exacerbates alpha-synucleinopathy in an A53T transgenic mouse model.
    Norris EH; Uryu K; Leight S; Giasson BI; Trojanowski JQ; Lee VM
    Am J Pathol; 2007 Feb; 170(2):658-66. PubMed ID: 17255333
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.