These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

243 related articles for article (PubMed ID: 30196060)

  • 1. Structure-based drug design: Synthesis and biological evaluation of quinazolin-4-amine derivatives as selective Aurora A kinase inhibitors.
    Long L; Wang YH; Zhuo JX; Tu ZC; Wu R; Yan M; Liu Q; Lu G
    Eur J Med Chem; 2018 Sep; 157():1361-1375. PubMed ID: 30196060
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Discovery of a Selective Aurora A Kinase Inhibitor by Virtual Screening.
    Kilchmann F; Marcaida MJ; Kotak S; Schick T; Boss SD; Awale M; Gönczy P; Reymond JL
    J Med Chem; 2016 Aug; 59(15):7188-211. PubMed ID: 27391133
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Design, synthesis, biological evaluation of 6-(2-amino-1H-benzo[d]imidazole-6-yl)quinazolin-4(3H)-one derivatives as novel anticancer agents with Aurora kinase inhibition.
    Fan C; Zhong T; Yang H; Yang Y; Wang D; Yang X; Xu Y; Fan Y
    Eur J Med Chem; 2020 Mar; 190():112108. PubMed ID: 32058239
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Design and synthesis of BPR1K653 derivatives targeting the back pocket of Aurora kinases for selective isoform inhibition.
    Ke YY; Chang CP; Lin WH; Tsai CH; Chiu IC; Wang WP; Wang PC; Chen PY; Lin WH; Chang CF; Kuo PC; Song JS; Shih C; Hsieh HP; Chi YH
    Eur J Med Chem; 2018 May; 151():533-545. PubMed ID: 29656197
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Development and biological evaluation of a novel aurora A kinase inhibitor.
    Sardon T; Cottin T; Xu J; Giannis A; Vernos I
    Chembiochem; 2009 Feb; 10(3):464-78. PubMed ID: 19199284
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Discovery of 4-aminoquinazoline--urea derivatives as Aurora kinase inhibitors with antiproliferative activity.
    Cai J; Li L; Hong KH; Wu X; Chen J; Wang P; Cao M; Zong X; Ji M
    Bioorg Med Chem; 2014 Nov; 22(21):5813-23. PubMed ID: 25270403
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Design, synthesis and bioevaluation of N-trisubstituted pyrimidine derivatives as potent aurora A kinase inhibitors.
    Luo Y; Deng YQ; Wang J; Long ZJ; Tu ZC; Peng W; Zhang JQ; Liu Q; Lu G
    Eur J Med Chem; 2014 May; 78():65-71. PubMed ID: 24681066
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Design, synthesis and biological activity of N
    Kurup S; McAllister B; Liskova P; Mistry T; Fanizza A; Stanford D; Slawska J; Keller U; Hoellein A
    J Enzyme Inhib Med Chem; 2018 Dec; 33(1):74-84. PubMed ID: 29115879
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Click approach to the discovery of 1,2,3-triazolylsalicylamides as potent Aurora kinase inhibitors.
    Song D; Park Y; Yoon J; Aman W; Hah JM; Ryu JS
    Bioorg Med Chem; 2014 Sep; 22(17):4855-66. PubMed ID: 25042560
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthesis and biological evaluation of aurora kinases inhibitors based on N-trisubstituted pyrimidine scaffold.
    Long L; Luo Y; Hou ZJ; Ma HJ; Long ZJ; Tu ZC; Huang LJ; Liu Q; Lu G
    Eur J Med Chem; 2018 Feb; 145():805-812. PubMed ID: 29358147
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Structure-Based Discovery and Bioactivity Evaluation of Novel Aurora-A Kinase Inhibitors as Anticancer Agents via Docking-Based Comparative Intermolecular Contacts Analysis (dbCICA).
    Hijjawi MS; Abutayeh RF; Taha MO
    Molecules; 2020 Dec; 25(24):. PubMed ID: 33353031
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Discovery of novel inhibitors of Aurora kinases with indazole scaffold: In silico fragment-based and knowledge-based drug design.
    Chang CF; Lin WH; Ke YY; Lin YS; Wang WC; Chen CH; Kuo PC; Hsu JTA; Uang BJ; Hsieh HP
    Eur J Med Chem; 2016 Nov; 124():186-199. PubMed ID: 27573544
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Facile identification of dual FLT3-Aurora A inhibitors: a computer-guided drug design approach.
    Chang Hsu Y; Ke YY; Shiao HY; Lee CC; Lin WH; Chen CH; Yen KJ; Hsu JT; Chang C; Hsieh HP
    ChemMedChem; 2014 May; 9(5):953-61. PubMed ID: 24665000
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Design and synthesis of Coenzyme A analogues as Aurora kinase A inhibitors: An exploration of the roles of the pyrophosphate and pantetheine moieties.
    Bellany F; Tsuchiya Y; Tran TM; Chan AWE; Allan H; Gout I; Tabor AB
    Bioorg Med Chem; 2020 Nov; 28(22):115740. PubMed ID: 33007553
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Design, Synthesis, and Biochemical Evaluation of New Triazole Derivatives as Aurora-A Kinase Inhibitors.
    Abdullah O
    Molecules; 2021 Sep; 26(18):. PubMed ID: 34577149
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Optimization and biological evaluation of 2-aminobenzothiazole derivatives as Aurora B kinase inhibitors.
    Lee E; An Y; Kwon J; Kim KI; Jeon R
    Bioorg Med Chem; 2017 Jul; 25(14):3614-3622. PubMed ID: 28529042
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Design, synthesis, biological activity evaluation of 3-(4-phenyl-1H-imidazol-2-yl)-1H-pyrazole derivatives as potent JAK 2/3 and aurora A/B kinases multi-targeted inhibitors.
    Zheng YG; Wang JA; Meng L; Pei X; Zhang L; An L; Li CL; Miao YL
    Eur J Med Chem; 2021 Jan; 209():112934. PubMed ID: 33109396
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Aurora isoform selectivity: design and synthesis of imidazo[4,5-b]pyridine derivatives as highly selective inhibitors of Aurora-A kinase in cells.
    Bavetsias V; Faisal A; Crumpler S; Brown N; Kosmopoulou M; Joshi A; Atrash B; Pérez-Fuertes Y; Schmitt JA; Boxall KJ; Burke R; Sun C; Avery S; Bush K; Henley A; Raynaud FI; Workman P; Bayliss R; Linardopoulos S; Blagg J
    J Med Chem; 2013 Nov; 56(22):9122-35. PubMed ID: 24195668
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Design, synthesis, quantum chemical studies and biological activity evaluation of pyrazole-benzimidazole derivatives as potent Aurora A/B kinase inhibitors.
    Zheng Y; Zheng M; Ling X; Liu Y; Xue Y; An L; Gu N; Ji M
    Bioorg Med Chem Lett; 2013 Jun; 23(12):3523-30. PubMed ID: 23664099
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Optimization and biological evaluation of nicotinamide derivatives as Aurora kinase inhibitors.
    Qi B; Xu X; Yang Y; He H; Yue X
    Bioorg Med Chem; 2019 Sep; 27(17):3825-3835. PubMed ID: 31307762
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.