BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

219 related articles for article (PubMed ID: 30196066)

  • 1. Triptolide enhances chemotherapeutic efficacy of antitumor drugs in non-small-cell lung cancer cells by inhibiting Nrf2-ARE activity.
    Zhu J; Wang H; Chen F; Lv H; Xu Z; Fu J; Hou Y; Xu Y; Pi J
    Toxicol Appl Pharmacol; 2018 Nov; 358():1-9. PubMed ID: 30196066
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The triptolide derivative MRx102 inhibits Wnt pathway activation and has potent anti-tumor effects in lung cancer.
    Reno TA; Tong SW; Wu J; Fidler JM; Nelson R; Kim JY; Raz DJ
    BMC Cancer; 2016 Jul; 16():439. PubMed ID: 27400883
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Luteolin inhibits the Nrf2 signaling pathway and tumor growth in vivo.
    Chian S; Thapa R; Chi Z; Wang XJ; Tang X
    Biochem Biophys Res Commun; 2014 May; 447(4):602-8. PubMed ID: 24747074
    [TBL] [Abstract][Full Text] [Related]  

  • 4. RNAi-mediated silencing of nuclear factor erythroid-2-related factor 2 gene expression in non-small cell lung cancer inhibits tumor growth and increases efficacy of chemotherapy.
    Singh A; Boldin-Adamsky S; Thimmulappa RK; Rath SK; Ashush H; Coulter J; Blackford A; Goodman SN; Bunz F; Watson WH; Gabrielson E; Feinstein E; Biswal S
    Cancer Res; 2008 Oct; 68(19):7975-84. PubMed ID: 18829555
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Regulatory role of KEAP1 and NRF2 in PPARγ expression and chemoresistance in human non-small-cell lung carcinoma cells.
    Zhan L; Zhang H; Zhang Q; Woods CG; Chen Y; Xue P; Dong J; Tokar EJ; Xu Y; Hou Y; Fu J; Yarborough K; Wang A; Qu W; Waalkes MP; Andersen ME; Pi J
    Free Radic Biol Med; 2012 Aug; 53(4):758-68. PubMed ID: 22684020
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Ginsenoside Rd reverses cisplatin resistance in non-small-cell lung cancer A549 cells by downregulating the nuclear factor erythroid 2-related factor 2 pathway.
    Chian S; Zhao Y; Xu M; Yu X; Ke X; Gao R; Yin L
    Anticancer Drugs; 2019 Sep; 30(8):838-845. PubMed ID: 31415285
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Targeted inhibition of the HNF1A/SHH axis by triptolide overcomes paclitaxel resistance in non-small cell lung cancer.
    Li LB; Yang LX; Liu L; Liu FR; Li AH; Zhu YL; Wen H; Xue X; Tian ZX; Sun H; Li PC; Zhao XG
    Acta Pharmacol Sin; 2024 May; 45(5):1060-1076. PubMed ID: 38228910
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Pulmonary delivery of triptolide-loaded liposomes decorated with anti-carbonic anhydrase IX antibody for lung cancer therapy.
    Lin C; Wong BCK; Chen H; Bian Z; Zhang G; Zhang X; Kashif Riaz M; Tyagi D; Lin G; Zhang Y; Wang J; Lu A; Yang Z
    Sci Rep; 2017 Apr; 7(1):1097. PubMed ID: 28428618
    [TBL] [Abstract][Full Text] [Related]  

  • 9. An effective strategy for increasing the radiosensitivity of Human lung Cancer cells by blocking Nrf2-dependent antioxidant responses.
    Lee S; Lim MJ; Kim MH; Yu CH; Yun YS; Ahn J; Song JY
    Free Radic Biol Med; 2012 Aug; 53(4):807-16. PubMed ID: 22684019
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Triptolide suppresses the growth and metastasis of non-small cell lung cancer by inhibiting β-catenin-mediated epithelial-mesenchymal transition.
    Deng QD; Lei XP; Zhong YH; Chen MS; Ke YY; Li Z; Chen J; Huang LJ; Zhang Y; Liang L; Lin ZX; Liu Q; Li SP; Yu XY
    Acta Pharmacol Sin; 2021 Sep; 42(9):1486-1497. PubMed ID: 33893396
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Triptolide sensitizes liver cancer cell lines to chemotherapy in vitro and in vivo.
    Li Y; Hu S
    Panminerva Med; 2014 Sep; 56(3):211-20. PubMed ID: 24352031
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Inhibition of PDGFR by CP-673451 induces apoptosis and increases cisplatin cytotoxicity in NSCLC cells via inhibiting the Nrf2-mediated defense mechanism.
    Yang Y; Deng Y; Chen X; Zhang J; Chen Y; Li H; Wu Q; Yang Z; Zhang L; Liu B
    Toxicol Lett; 2018 Oct; 295():88-98. PubMed ID: 29857117
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Triptolide decreases expression of latency-associated nuclear antigen 1 and reduces viral titers in Kaposi's sarcoma-associated and herpesvirus-related primary effusion lymphoma cells.
    Long C; Guo W; Zhou H; Wang J; Wang H; Sun X
    Int J Oncol; 2016 Apr; 48(4):1519-30. PubMed ID: 26821279
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Triptolide inhibits epithelial‑mesenchymal transition and induces apoptosis in gefitinib‑resistant lung cancer cells.
    Li F; Cui H; Jin X; Gong X; Wang W; Wang J
    Oncol Rep; 2020 May; 43(5):1569-1579. PubMed ID: 32323848
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Dysfunctional KEAP1-NRF2 interaction in non-small-cell lung cancer.
    Singh A; Misra V; Thimmulappa RK; Lee H; Ames S; Hoque MO; Herman JG; Baylin SB; Sidransky D; Gabrielson E; Brock MV; Biswal S
    PLoS Med; 2006 Oct; 3(10):e420. PubMed ID: 17020408
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Triptolide inhibits Wnt signaling in NSCLC through upregulation of multiple Wnt inhibitory factors via epigenetic modifications to Histone H3.
    Nardi I; Reno T; Yun X; Sztain T; Wang J; Dai H; Zheng L; Shen B; Kim J; Raz D
    Int J Cancer; 2018 Nov; 143(10):2470-2478. PubMed ID: 30006924
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Triptolide interrupts rRNA synthesis and induces the RPL23‑MDM2‑p53 pathway to repress lung cancer cells.
    Wang J; Zhang ZQ; Li FQ; Chen JN; Gong X; Cao BB; Wang W
    Oncol Rep; 2020 Jun; 43(6):1863-1874. PubMed ID: 32236588
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A Novel Nrf2 Pathway Inhibitor Sensitizes Keap1-Mutant Lung Cancer Cells to Chemotherapy.
    Zhang D; Hou Z; Aldrich KE; Lockwood L; Odom AL; Liby KT
    Mol Cancer Ther; 2021 Sep; 20(9):1692-1701. PubMed ID: 34158350
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Keap1-Nrf2 Interaction Suppresses Cell Motility in Lung Adenocarcinomas by Targeting the S100P Protein.
    Chien MH; Lee WJ; Hsieh FK; Li CF; Cheng TY; Wang MY; Chen JS; Chow JM; Jan YH; Hsiao M; Hua KT; Kuo ML
    Clin Cancer Res; 2015 Oct; 21(20):4719-32. PubMed ID: 26078391
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Small Molecule Inhibitor of NRF2 Selectively Intervenes Therapeutic Resistance in KEAP1-Deficient NSCLC Tumors.
    Singh A; Venkannagari S; Oh KH; Zhang YQ; Rohde JM; Liu L; Nimmagadda S; Sudini K; Brimacombe KR; Gajghate S; Ma J; Wang A; Xu X; Shahane SA; Xia M; Woo J; Mensah GA; Wang Z; Ferrer M; Gabrielson E; Li Z; Rastinejad F; Shen M; Boxer MB; Biswal S
    ACS Chem Biol; 2016 Nov; 11(11):3214-3225. PubMed ID: 27552339
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.