257 related articles for article (PubMed ID: 30199704)
1. Design, synthesis and identification of novel substituted 2-amino thiazole analogues as potential anti-inflammatory agents targeting 5-lipoxygenase.
Sinha S; Doble M; Manju SL
Eur J Med Chem; 2018 Oct; 158():34-50. PubMed ID: 30199704
[TBL] [Abstract][Full Text] [Related]
2. Design, synthesis and identification of novel coumaperine derivatives for inhibition of human 5-LOX: Antioxidant, pseudoperoxidase and docking studies.
Muthuraman S; Sinha S; Vasavi CS; Waidha KM; Basu B; Munussami P; Balamurali MM; Doble M; Saravana Kumar R
Bioorg Med Chem; 2019 Feb; 27(4):604-619. PubMed ID: 30638966
[TBL] [Abstract][Full Text] [Related]
3. Novel class of benzimidazole-thiazole hybrids: The privileged scaffolds of potent anti-inflammatory activity with dual inhibition of cyclooxygenase and 15-lipoxygenase enzymes.
Maghraby MT; Abou-Ghadir OMF; Abdel-Moty SG; Ali AY; Salem OIA
Bioorg Med Chem; 2020 Apr; 28(7):115403. PubMed ID: 32127262
[TBL] [Abstract][Full Text] [Related]
4. Synthesis and biological evaluation of N-aryl-4-aryl-1,3-thiazole-2-amine derivatives as direct 5-lipoxygenase inhibitors.
Suh J; Yum EK; Cheon HG; Cho YS
Chem Biol Drug Des; 2012 Jul; 80(1):89-98. PubMed ID: 22404847
[TBL] [Abstract][Full Text] [Related]
5. Design, synthesis, and biological evaluation of novel 1,2-diaryl-4-substituted-benzylidene-5(4H)-imidazolone derivatives as cytotoxic agents and COX-2/LOX inhibitors.
Lamie PF; Philoppes JN; Rárová L
Arch Pharm (Weinheim); 2018 Apr; 351(3-4):e1700311. PubMed ID: 29400411
[TBL] [Abstract][Full Text] [Related]
6. Identification and development of thiazole leads as COX-2/5-LOX inhibitors through in-vitro and in-vivo biological evaluation for anti-inflammatory activity.
Jacob P J; Manju SL
Bioorg Chem; 2020 Jul; 100():103882. PubMed ID: 32361295
[TBL] [Abstract][Full Text] [Related]
7. Synthesis and Biological Evaluation of N-Aryl-5-aryloxazol-2-amine Derivatives as 5-Lipoxygenase Inhibitors.
Suh JH; Yum EK; Cho YS
Chem Pharm Bull (Tokyo); 2015; 63(8):573-8. PubMed ID: 26040270
[TBL] [Abstract][Full Text] [Related]
8. Pyrazole-hydrazone derivatives as anti-inflammatory agents: Design, synthesis, biological evaluation, COX-1,2/5-LOX inhibition and docking study.
Abdelgawad MA; Labib MB; Abdel-Latif M
Bioorg Chem; 2017 Oct; 74():212-220. PubMed ID: 28865292
[TBL] [Abstract][Full Text] [Related]
9. 5-Lipoxygenase as a drug target: A review on trends in inhibitors structural design, SAR and mechanism based approach.
Sinha S; Doble M; Manju SL
Bioorg Med Chem; 2019 Sep; 27(17):3745-3759. PubMed ID: 31331653
[TBL] [Abstract][Full Text] [Related]
10. Synthesis, anti-inflammatory, analgesic, 5-lipoxygenase (5-LOX) inhibition activities, and molecular docking study of 7-substituted coumarin derivatives.
Srivastava P; Vyas VK; Variya B; Patel P; Qureshi G; Ghate M
Bioorg Chem; 2016 Aug; 67():130-8. PubMed ID: 27376460
[TBL] [Abstract][Full Text] [Related]
11. Design, synthesis and biological evaluation of benzo[1.3.2]dithiazolium ylide 1,1-dioxide derivatives as potential dual cyclooxygenase-2/5-lipoxygenase inhibitors.
Tan CM; Chen GS; Chen CS; Chang PT; Chern JW
Bioorg Med Chem; 2011 Nov; 19(21):6316-28. PubMed ID: 21958737
[TBL] [Abstract][Full Text] [Related]
12. Development of 3,5-dinitrobenzoate-based 5-lipoxygenase inhibitors.
Shang E; Liu Y; Wu Y; Zhu W; He C; Lai L
Bioorg Med Chem; 2014 Apr; 22(8):2396-402. PubMed ID: 24685113
[TBL] [Abstract][Full Text] [Related]
13. Syntheses and characterization of nimesulide derivatives for dual enzyme inhibitors of both cyclooxygenase-1/2 and 5-lipoxygenase.
Li Y; Chen SH; Ou TM; Tan JH; Li D; Gu LQ; Huang ZS
Bioorg Med Chem; 2011 Mar; 19(6):2074-83. PubMed ID: 21349729
[TBL] [Abstract][Full Text] [Related]
14. Novel N-substituted indole Schiff bases as dual inhibitors of cyclooxygenase-2 and 5-lipoxygenase enzymes: Synthesis, biological activities in vitro and docking study.
Lamie PF; Ali WAM; Bazgier V; Rárová L
Eur J Med Chem; 2016 Nov; 123():803-813. PubMed ID: 27541263
[TBL] [Abstract][Full Text] [Related]
15. Imidazo[2,1-b]thiazole derivatives as new inhibitors of 15-lipoxygenase.
Tehrani MB; Emami S; Asadi M; Saeedi M; Mirzahekmati M; Ebrahimi SM; Mahdavi M; Nadri H; Moradi A; Moghadam FH; Farzipour S; Vosooghi M; Foroumadi A; Shafiee A
Eur J Med Chem; 2014 Nov; 87():759-64. PubMed ID: 25310714
[TBL] [Abstract][Full Text] [Related]
16. Design, synthesis, and biological evaluation of new pyrazoloquinazoline derivatives as dual COX-2/5-LOX inhibitors.
Shaaban MA; Kamal AM; Faggal SI; Farag NA; Aborehab NM; Elsahar AE; Mohamed KO
Arch Pharm (Weinheim); 2020 Nov; 353(11):e2000027. PubMed ID: 32696514
[TBL] [Abstract][Full Text] [Related]
17. Design, synthesis and pharmacobiological evaluation of novel acrylic acid derivatives acting as lipoxygenase and cyclooxygenase-1 inhibitors with antioxidant and anti-inflammatory activities.
Pontiki E; Hadjipavlou-Litina D; Litinas K; Nicolotti O; Carotti A
Eur J Med Chem; 2011 Jan; 46(1):191-200. PubMed ID: 21106277
[TBL] [Abstract][Full Text] [Related]
18. Optimization of benzoquinone and hydroquinone derivatives as potent inhibitors of human 5-lipoxygenase.
Peduto A; Scuotto M; Krauth V; Roviezzo F; Rossi A; Temml V; Esposito V; Stuppner H; Schuster D; D'Agostino B; Schiraldi C; de Rosa M; Werz O; Filosa R
Eur J Med Chem; 2017 Feb; 127():715-726. PubMed ID: 27836196
[TBL] [Abstract][Full Text] [Related]
19. Identification of NSAIDs as lipoxygenase inhibitors through highly sensitive chemiluminescence method, expression analysis in mononuclear cells and computational studies.
Shahid W; Ejaz SA; Al-Rashida M; Saleem M; Ahmed M; Rahman J; Riaz N; Ashraf M
Bioorg Chem; 2021 May; 110():104818. PubMed ID: 33784531
[TBL] [Abstract][Full Text] [Related]
20. Synthesis and biological evaluation of purine-pyrazole hybrids incorporating thiazole, thiazolidinone or rhodanine moiety as 15-LOX inhibitors endowed with anticancer and antioxidant potential.
Afifi OS; Shaaban OG; Abd El Razik HA; Shams El-Dine SEA; Ashour FA; El-Tombary AA; Abu-Serie MM
Bioorg Chem; 2019 Jun; 87():821-837. PubMed ID: 30999135
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
