BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

280 related articles for article (PubMed ID: 30203046)

  • 1. Chemical Activation of the Constitutive Androstane Receptor Leads to Activation of Oxidant-Induced Nrf2.
    Rooney JP; Oshida K; Kumar R; Baldwin WS; Corton JC
    Toxicol Sci; 2019 Jan; 167(1):172-189. PubMed ID: 30203046
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Drug metabolizing enzyme induction pathways in experimental non-alcoholic steatohepatitis.
    Fisher CD; Jackson JP; Lickteig AJ; Augustine LM; Cherrington NJ
    Arch Toxicol; 2008 Dec; 82(12):959-64. PubMed ID: 18488193
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Constitutive androstane receptor (CAR) mediates dieldrin-induced liver tumorigenesis in mouse.
    Wang Z; Wu Q; Li X; Klaunig JE
    Arch Toxicol; 2020 Aug; 94(8):2873-2884. PubMed ID: 32435917
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Compensatory changes in CYP expression in three different toxicology mouse models: CAR-null, Cyp3a-null, and Cyp2b9/10/13-null mice.
    Kumar R; Mota LC; Litoff EJ; Rooney JP; Boswell WT; Courter E; Henderson CM; Hernandez JP; Corton JC; Moore DD; Baldwin WS
    PLoS One; 2017; 12(3):e0174355. PubMed ID: 28350814
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Activation of nuclear receptor CAR by an environmental pollutant perfluorooctanoic acid.
    Abe T; Takahashi M; Kano M; Amaike Y; Ishii C; Maeda K; Kudoh Y; Morishita T; Hosaka T; Sasaki T; Kodama S; Matsuzawa A; Kojima H; Yoshinari K
    Arch Toxicol; 2017 Jun; 91(6):2365-2374. PubMed ID: 27832320
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Perfluorocarboxylic acids induce cytochrome P450 enzymes in mouse liver through activation of PPAR-alpha and CAR transcription factors.
    Cheng X; Klaassen CD
    Toxicol Sci; 2008 Nov; 106(1):29-36. PubMed ID: 18648086
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Identification of chemical modulators of the constitutive activated receptor (CAR) in a gene expression compendium.
    Oshida K; Vasani N; Jones C; Moore T; Hester S; Nesnow S; Auerbach S; Geter DR; Aleksunes LM; Thomas RS; Applegate D; Klaassen CD; Corton JC
    Nucl Recept Signal; 2015; 13():e002. PubMed ID: 25949234
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Coordinated regulation of hepatic phase I and II drug-metabolizing genes and transporters using AhR-, CAR-, PXR-, PPARα-, and Nrf2-null mice.
    Aleksunes LM; Klaassen CD
    Drug Metab Dispos; 2012 Jul; 40(7):1366-79. PubMed ID: 22496397
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Induction of drug-metabolizing enzymes by garlic and allyl sulfide compounds via activation of constitutive androstane receptor and nuclear factor E2-related factor 2.
    Fisher CD; Augustine LM; Maher JM; Nelson DM; Slitt AL; Klaassen CD; Lehman-McKeeman LD; Cherrington NJ
    Drug Metab Dispos; 2007 Jun; 35(6):995-1000. PubMed ID: 17353348
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Xenobiotic-induced hepatocyte proliferation associated with constitutive active/androstane receptor (CAR) or peroxisome proliferator-activated receptor α (PPARα) is enhanced by pregnane X receptor (PXR) activation in mice.
    Shizu R; Benoki S; Numakura Y; Kodama S; Miyata M; Yamazoe Y; Yoshinari K
    PLoS One; 2013; 8(4):e61802. PubMed ID: 23626729
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Induction of mouse UDP-glucuronosyltransferase mRNA expression in liver and intestine by activators of aryl-hydrocarbon receptor, constitutive androstane receptor, pregnane X receptor, peroxisome proliferator-activated receptor alpha, and nuclear factor erythroid 2-related factor 2.
    Buckley DB; Klaassen CD
    Drug Metab Dispos; 2009 Apr; 37(4):847-56. PubMed ID: 19144771
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Protein Kinase N Family Negatively Regulates Constitutive Androstane Receptor-Mediated Transcriptional Induction of Cytochrome P450 2b10 in the Livers of Mice.
    Kawase A; Mukai H; Tateishi S; Kuroda S; Kazaoka A; Satoh R; Shimada H; Sugiura R; Iwaki M
    J Pharmacol Exp Ther; 2021 Oct; 379(1):53-63. PubMed ID: 34312179
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Characterization of peroxisome proliferator-activated receptor alpha--independent effects of PPARalpha activators in the rodent liver: di-(2-ethylhexyl) phthalate also activates the constitutive-activated receptor.
    Ren H; Aleksunes LM; Wood C; Vallanat B; George MH; Klaassen CD; Corton JC
    Toxicol Sci; 2010 Jan; 113(1):45-59. PubMed ID: 19850644
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The role of mouse and human peroxisome proliferator-activated receptor-α in modulating the hepatic effects of perfluorooctane sulfonate in mice.
    Su S; Billy LJ; Chang S; Gonzalez FJ; Patterson AD; Peters JM
    Toxicology; 2022 Jan; 465():153056. PubMed ID: 34861291
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Induction of nuclear translocation of constitutive androstane receptor by peroxisome proliferator-activated receptor alpha synthetic ligands in mouse liver.
    Guo D; Sarkar J; Suino-Powell K; Xu Y; Matsumoto K; Jia Y; Yu S; Khare S; Haldar K; Rao MS; Foreman JE; Monga SP; Peters JM; Xu HE; Reddy JK
    J Biol Chem; 2007 Dec; 282(50):36766-76. PubMed ID: 17962186
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Stilbene compound trans-3,4,5,4´-tetramethoxystilbene, a potential anticancer drug, regulates constitutive androstane receptor (Car) target genes, but does not possess proliferative activity in mouse liver.
    Dusek J; Skoda J; Holas O; Horvatova A; Smutny T; Linhartova L; Hirsova P; Kucera O; Micuda S; Braeuning A; Pavek P
    Toxicol Lett; 2019 Oct; 313():1-10. PubMed ID: 31170421
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Regulation of mouse organic anion-transporting polypeptides (Oatps) in liver by prototypical microsomal enzyme inducers that activate distinct transcription factor pathways.
    Cheng X; Maher J; Dieter MZ; Klaassen CD
    Drug Metab Dispos; 2005 Sep; 33(9):1276-82. PubMed ID: 15919853
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Specific and overlapping functions of the nuclear hormone receptors CAR and PXR in xenobiotic response.
    Wei P; Zhang J; Dowhan DH; Han Y; Moore DD
    Pharmacogenomics J; 2002; 2(2):117-26. PubMed ID: 12049174
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Clofibric acid induces hepatic CYP 2B1/2 via constitutive androstane receptor not via peroxisome proliferator activated receptor alpha in rat.
    Ibrahim ZS; Ahmed MM; El-Shazly SA; Ishizuka M; Fujita S
    Biosci Biotechnol Biochem; 2014; 78(9):1550-9. PubMed ID: 25052003
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Importance of hepatic induction of constitutive androstane receptor and other transcription factors that regulate xenobiotic metabolism and transport.
    Petrick JS; Klaassen CD
    Drug Metab Dispos; 2007 Oct; 35(10):1806-15. PubMed ID: 17627975
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.