BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

166 related articles for article (PubMed ID: 30204052)

  • 21. Aza-SAHA Derivatives Are Selective Histone Deacetylase 10 Chemical Probes That Inhibit Polyamine Deacetylation and Phenocopy HDAC10 Knockout.
    Steimbach RR; Herbst-Gervasoni CJ; Lechner S; Stewart TM; Klinke G; Ridinger J; Géraldy MNE; Tihanyi G; Foley JR; Uhrig U; Kuster B; Poschet G; Casero RA; Médard G; Oehme I; Christianson DW; Gunkel N; Miller AK
    J Am Chem Soc; 2022 Oct; 144(41):18861-18875. PubMed ID: 36200994
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Histone deacetylase 10: A polyamine deacetylase from the crystal structure to the first inhibitors.
    Lambona C; Zwergel C; Fioravanti R; Valente S; Mai A
    Curr Opin Struct Biol; 2023 Oct; 82():102668. PubMed ID: 37542907
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Identification of potent HDAC 2 inhibitors using E-pharmacophore modelling, structure-based virtual screening and molecular dynamic simulation.
    Pai P; Kumar A; Shetty MG; Kini SG; Krishna MB; Satyamoorthy K; Babitha KS
    J Mol Model; 2022 Apr; 28(5):119. PubMed ID: 35419753
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Combined pharmacophore modeling, 3D-QSAR and docking studies to identify novel HDAC inhibitors using drug repurposing.
    Liu J; Zhu Y; He Y; Zhu H; Gao Y; Li Z; Zhu J; Sun X; Fang F; Wen H; Li W
    J Biomol Struct Dyn; 2020 Feb; 38(2):533-547. PubMed ID: 30938574
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Design and synthesis of benzodiazepine analogs as isoform-selective human lysine deacetylase inhibitors.
    Reddy DR; Ballante F; Zhou NJ; Marshall GR
    Eur J Med Chem; 2017 Feb; 127():531-553. PubMed ID: 28109947
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Energy-optimised pharmacophore approach to identify potential hotspots during inhibition of Class II HDAC isoforms.
    Ganai SA; Shanmugam K; Mahadevan V
    J Biomol Struct Dyn; 2015; 33(2):374-87. PubMed ID: 24460542
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Structural basis for the design and synthesis of selective HDAC inhibitors.
    Di Micco S; Chini MG; Terracciano S; Bruno I; Riccio R; Bifulco G
    Bioorg Med Chem; 2013 Jul; 21(13):3795-807. PubMed ID: 23693069
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Polyamine Deacetylase Structure and Catalysis: Prokaryotic Acetylpolyamine Amidohydrolase and Eukaryotic HDAC10.
    Shinsky SA; Christianson DW
    Biochemistry; 2018 Jun; 57(22):3105-3114. PubMed ID: 29533602
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Homology modeling, force field design, and free energy simulation studies to optimize the activities of histone deacetylase inhibitors.
    Park H; Lee S
    J Comput Aided Mol Des; 2004 Jun; 18(6):375-88. PubMed ID: 15662999
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Isolation and characterization of mammalian HDAC10, a novel histone deacetylase.
    Kao HY; Lee CH; Komarov A; Han CC; Evans RM
    J Biol Chem; 2002 Jan; 277(1):187-93. PubMed ID: 11677242
    [TBL] [Abstract][Full Text] [Related]  

  • 31. X-ray Crystallographic Snapshots of Substrate Binding in the Active Site of Histone Deacetylase 10.
    Herbst-Gervasoni CJ; Christianson DW
    Biochemistry; 2021 Feb; 60(4):303-313. PubMed ID: 33449614
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Structure-based virtual screening for novel potential selective inhibitors of class IIa histone deacetylases for cancer treatment.
    Elmezayen AD; Kemal Y
    Comput Biol Chem; 2021 Jun; 92():107491. PubMed ID: 33930743
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Exploring inhibitor release pathways in histone deacetylases using random acceleration molecular dynamics simulations.
    Kalyaanamoorthy S; Chen YP
    J Chem Inf Model; 2012 Feb; 52(2):589-603. PubMed ID: 22263580
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Pharmacophore-enabled virtual screening, molecular docking and molecular dynamics studies for identification of potent and selective histone deacetylase 8 inhibitors.
    Kashyap K; Kakkar R
    Comput Biol Med; 2020 Aug; 123():103850. PubMed ID: 32658783
    [TBL] [Abstract][Full Text] [Related]  

  • 35. In Silico Identification of Potential Inhibitor Against a Fungal Histone Deacetylase, RPD3 from
    Shanmugam G; Kim T; Jeon J
    Molecules; 2019 May; 24(11):. PubMed ID: 31151320
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Molecular docking and molecular dynamics study on SmHDAC1 to identify potential lead compounds against Schistosomiasis.
    Singh R; Pandey PN
    Mol Biol Rep; 2015 Mar; 42(3):689-98. PubMed ID: 25663090
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Identification of HDAC10, a novel class II human histone deacetylase containing a leucine-rich domain.
    Tong JJ; Liu J; Bertos NR; Yang XJ
    Nucleic Acids Res; 2002 Mar; 30(5):1114-23. PubMed ID: 11861901
    [TBL] [Abstract][Full Text] [Related]  

  • 38. QSAR modeling to design selective histone deacetylase 8 (HDAC8) inhibitors.
    Cao GP; Thangapandian S; Son M; Kumar R; Choi YJ; Kim Y; Kwon YJ; Kim HH; Suh JK; Lee KW
    Arch Pharm Res; 2016 Oct; 39(10):1356-1369. PubMed ID: 27542119
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Insights into intermolecular interactions, electrostatic properties and the stability of C646 in the binding pocket of p300 histone acetyltransferase enzyme: a combined molecular dynamics and charge density study.
    Sivanandam M; Saravanan K; Kumaradhas P
    J Biomol Struct Dyn; 2018 Sep; 36(12):3246-3264. PubMed ID: 28948877
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Phenolic compounds as histone deacetylase inhibitors: binding propensity and interaction insights from molecular docking and dynamics simulations.
    Uba AI; Zengin G
    Amino Acids; 2023 May; 55(5):579-593. PubMed ID: 36781452
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 9.