228 related articles for article (PubMed ID: 30206207)
1. Ceramide synthase-6 confers resistance to chemotherapy by binding to CD95/Fas in T-cell acute lymphoblastic leukemia.
Verlekar D; Wei SJ; Cho H; Yang S; Kang MH
Cell Death Dis; 2018 Sep; 9(9):925. PubMed ID: 30206207
[TBL] [Abstract][Full Text] [Related]
2. Expression of Ceramide Synthase 6 Transcriptionally Activates Acid Ceramidase in a c-Jun N-terminal Kinase (JNK)-dependent Manner.
Tirodkar TS; Lu P; Bai A; Scheffel MJ; Gencer S; Garrett-Mayer E; Bielawska A; Ogretmen B; Voelkel-Johnson C
J Biol Chem; 2015 May; 290(21):13157-67. PubMed ID: 25839235
[TBL] [Abstract][Full Text] [Related]
3. The equilibrium between long and very long chain ceramides is important for the fate of the cell and can be influenced by co-expression of CerS.
Hartmann D; Wegner MS; Wanger RA; Ferreirós N; Schreiber Y; Lucks J; Schiffmann S; Geisslinger G; Grösch S
Int J Biochem Cell Biol; 2013 Jul; 45(7):1195-203. PubMed ID: 23538298
[TBL] [Abstract][Full Text] [Related]
4. The role of C16:0 ceramide in the development of obesity and type 2 diabetes: CerS6 inhibition as a novel therapeutic approach.
Raichur S; Brunner B; Bielohuby M; Hansen G; Pfenninger A; Wang B; Bruning JC; Larsen PJ; Tennagels N
Mol Metab; 2019 Mar; 21():36-50. PubMed ID: 30655217
[TBL] [Abstract][Full Text] [Related]
5. Ceramide Synthase 6 Is a Novel Target of Methotrexate Mediating Its Antiproliferative Effect in a p53-Dependent Manner.
Fekry B; Esmaeilniakooshkghazi A; Krupenko SA; Krupenko NI
PLoS One; 2016; 11(1):e0146618. PubMed ID: 26783755
[TBL] [Abstract][Full Text] [Related]
6. Antiapoptotic roles of ceramide-synthase-6-generated C16-ceramide via selective regulation of the ATF6/CHOP arm of ER-stress-response pathways.
Senkal CE; Ponnusamy S; Bielawski J; Hannun YA; Ogretmen B
FASEB J; 2010 Jan; 24(1):296-308. PubMed ID: 19723703
[TBL] [Abstract][Full Text] [Related]
7. Alteration of ceramide synthase 6/C16-ceramide induces activating transcription factor 6-mediated endoplasmic reticulum (ER) stress and apoptosis via perturbation of cellular Ca2+ and ER/Golgi membrane network.
Senkal CE; Ponnusamy S; Manevich Y; Meyers-Needham M; Saddoughi SA; Mukhopadyay A; Dent P; Bielawski J; Ogretmen B
J Biol Chem; 2011 Dec; 286(49):42446-42458. PubMed ID: 22013072
[TBL] [Abstract][Full Text] [Related]
8. Mechanism of synergy of N-(4-hydroxyphenyl)retinamide and ABT-737 in acute lymphoblastic leukemia cell lines: Mcl-1 inactivation.
Kang MH; Wan Z; Kang YH; Sposto R; Reynolds CP
J Natl Cancer Inst; 2008 Apr; 100(8):580-95. PubMed ID: 18398104
[TBL] [Abstract][Full Text] [Related]
9. Developmentally regulated ceramide synthase 6 increases mitochondrial Ca2+ loading capacity and promotes apoptosis.
Novgorodov SA; Chudakova DA; Wheeler BW; Bielawski J; Kindy MS; Obeid LM; Gudz TI
J Biol Chem; 2011 Feb; 286(6):4644-58. PubMed ID: 21148554
[TBL] [Abstract][Full Text] [Related]
10. By activating Fas/ceramide synthase 6/p38 kinase in lipid rafts, stichoposide D inhibits growth of leukemia xenografts.
Yun SH; Park ES; Shin SW; Ju MH; Han JY; Jeong JS; Kim SH; Stonik VA; Kwak JY; Park JI
Oncotarget; 2015 Sep; 6(29):27596-612. PubMed ID: 26318294
[TBL] [Abstract][Full Text] [Related]
11. Combining CAR T cells and the Bcl-2 family apoptosis inhibitor ABT-737 for treating B-cell malignancy.
Karlsson H; Lindqvist AC; Fransson M; Paul-Wetterberg G; Nilsson B; Essand M; Nilsson K; Frisk P; Jernberg-Wiklund H; Loskog A
Cancer Gene Ther; 2013 Jul; 20(7):386-93. PubMed ID: 23788110
[TBL] [Abstract][Full Text] [Related]
12. RNA silencing of Mcl-1 enhances ABT-737-mediated apoptosis in melanoma: role for a caspase-8-dependent pathway.
Keuling AM; Felton KE; Parker AA; Akbari M; Andrew SE; Tron VA
PLoS One; 2009 Aug; 4(8):e6651. PubMed ID: 19684859
[TBL] [Abstract][Full Text] [Related]
13. BCL2 Inhibitor (ABT-737): A Restorer of Prednisolone Sensitivity in Early T-Cell Precursor-Acute Lymphoblastic Leukemia with High MEF2C Expression?
Kawashima-Goto S; Imamura T; Tomoyasu C; Yano M; Yoshida H; Fujiki A; Tamura S; Osone S; Ishida H; Morimoto A; Kuroda H; Hosoi H
PLoS One; 2015; 10(7):e0132926. PubMed ID: 26172269
[TBL] [Abstract][Full Text] [Related]
14. Dependence of ABCB1 transporter expression and function on distinct sphingolipids generated by ceramide synthases-2 and -6 in chemoresistant renal cancer.
Lee WK; Maaß M; Quach A; Poscic N; Prangley H; Pallott EC; Kim JL; Pierce JS; Ogretmen B; Futerman AH; Thévenod F
J Biol Chem; 2022 Feb; 298(2):101492. PubMed ID: 34915026
[TBL] [Abstract][Full Text] [Related]
15. Adoptive Transfer of Ceramide Synthase 6 Deficient Splenocytes Reduces the Development of Colitis.
Scheffel MJ; Helke K; Lu P; Bowers JS; Ogretmen B; Garrett-Mayer E; Paulos CM; Voelkel-Johnson C
Sci Rep; 2017 Nov; 7(1):15552. PubMed ID: 29138469
[TBL] [Abstract][Full Text] [Related]
16. Co-targeting of Bcl-2 and mTOR pathway triggers synergistic apoptosis in BH3 mimetics resistant acute lymphoblastic leukemia.
Iacovelli S; Ricciardi MR; Allegretti M; Mirabilii S; Licchetta R; Bergamo P; Rinaldo C; Zeuner A; Foà R; Milella M; McCubrey JA; Martelli AM; Tafuri A
Oncotarget; 2015 Oct; 6(31):32089-103. PubMed ID: 26392332
[TBL] [Abstract][Full Text] [Related]
17. Combination of ABT-737 and resveratrol enhances DNA damage and apoptosis in human T-cell acute lymphoblastic leukemia MOLT-4 cells.
Opydo-Chanek M; Rak A; Cierniak A; Mazur L
Toxicol In Vitro; 2017 Aug; 42():38-46. PubMed ID: 28366708
[TBL] [Abstract][Full Text] [Related]
18. Cytotoxicity, drug combinability, and biological correlates of ABT-737 against acute lymphoblastic leukemia cells with MLL rearrangement.
Jayanthan A; Incoronato A; Singh A; Blackmore C; Bernoux D; Lewis V; Stam R; Whitlock JA; Narendran A
Pediatr Blood Cancer; 2011 Mar; 56(3):353-60. PubMed ID: 21225911
[TBL] [Abstract][Full Text] [Related]
19. Activation of ceramide synthase 6 by celecoxib leads to a selective induction of C16:0-ceramide.
Schiffmann S; Ziebell S; Sandner J; Birod K; Deckmann K; Hartmann D; Rode S; Schmidt H; Angioni C; Geisslinger G; Grösch S
Biochem Pharmacol; 2010 Dec; 80(11):1632-40. PubMed ID: 20735991
[TBL] [Abstract][Full Text] [Related]
20. Influence of Bcl-2 family members on the cellular response of small-cell lung cancer cell lines to ABT-737.
Tahir SK; Yang X; Anderson MG; Morgan-Lappe SE; Sarthy AV; Chen J; Warner RB; Ng SC; Fesik SW; Elmore SW; Rosenberg SH; Tse C
Cancer Res; 2007 Feb; 67(3):1176-83. PubMed ID: 17283153
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
