BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

231 related articles for article (PubMed ID: 30206207)

  • 21. Folate stress induces apoptosis via p53-dependent de novo ceramide synthesis and up-regulation of ceramide synthase 6.
    Hoeferlin LA; Fekry B; Ogretmen B; Krupenko SA; Krupenko NI
    J Biol Chem; 2013 May; 288(18):12880-90. PubMed ID: 23519469
    [TBL] [Abstract][Full Text] [Related]  

  • 22. 'Seed' analysis of off-target siRNAs reveals an essential role of Mcl-1 in resistance to the small-molecule Bcl-2/Bcl-XL inhibitor ABT-737.
    Lin X; Morgan-Lappe S; Huang X; Li L; Zakula DM; Vernetti LA; Fesik SW; Shen Y
    Oncogene; 2007 Jun; 26(27):3972-9. PubMed ID: 17173063
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Short-chain C6 ceramide sensitizes AT406-induced anti-pancreatic cancer cell activity.
    Zhao X; Sun B; Zhang J; Zhang R; Zhang Q
    Biochem Biophys Res Commun; 2016 Oct; 479(2):166-172. PubMed ID: 27562715
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Targeting ceramide synthase 6-dependent metastasis-prone phenotype in lung cancer cells.
    Suzuki M; Cao K; Kato S; Komizu Y; Mizutani N; Tanaka K; Arima C; Tai MC; Yanagisawa K; Togawa N; Shiraishi T; Usami N; Taniguchi T; Fukui T; Yokoi K; Wakahara K; Hasegawa Y; Mizutani Y; Igarashi Y; Inokuchi J; Iwaki S; Fujii S; Satou A; Matsumoto Y; Ueoka R; Tamiya-Koizumi K; Murate T; Nakamura M; Kyogashima M; Takahashi T
    J Clin Invest; 2016 Jan; 126(1):254-65. PubMed ID: 26650179
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Ceramide synthase 6 knockdown suppresses apoptosis after photodynamic therapy in human head and neck squamous carcinoma cells.
    Separovic D; Breen P; Joseph N; Bielawski J; Pierce JS; VAN Buren E; Gudz TI
    Anticancer Res; 2012 Mar; 32(3):753-60. PubMed ID: 22399588
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Very long chain ceramides interfere with C16-ceramide-induced channel formation: A plausible mechanism for regulating the initiation of intrinsic apoptosis.
    Stiban J; Perera M
    Biochim Biophys Acta; 2015 Feb; 1848(2):561-7. PubMed ID: 25462172
    [TBL] [Abstract][Full Text] [Related]  

  • 27. C16‑ceramide and sphingosine 1‑phosphate/S1PR2 have opposite effects on cell growth through mTOR signaling pathway regulation.
    Kim MH; Park JW; Lee EJ; Kim S; Shin SH; Ahn JH; Jung Y; Park I; Park WJ
    Oncol Rep; 2018 Nov; 40(5):2977-2987. PubMed ID: 30226616
    [TBL] [Abstract][Full Text] [Related]  

  • 28. ABT-737 increases tyrosine kinase inhibitor-induced apoptosis in chronic myeloid leukemia cells through XIAP downregulation and sensitizes CD34(+) CD38(-) population to imatinib.
    Airiau K; Mahon FX; Josselin M; Jeanneteau M; Turcq B; Belloc F
    Exp Hematol; 2012 May; 40(5):367-78.e2. PubMed ID: 22240609
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Obesity-induced CerS6-dependent C16:0 ceramide production promotes weight gain and glucose intolerance.
    Turpin SM; Nicholls HT; Willmes DM; Mourier A; Brodesser S; Wunderlich CM; Mauer J; Xu E; Hammerschmidt P; Brönneke HS; Trifunovic A; LoSasso G; Wunderlich FT; Kornfeld JW; Blüher M; Krönke M; Brüning JC
    Cell Metab; 2014 Oct; 20(4):678-86. PubMed ID: 25295788
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Ionizing radiation sensitizes breast cancer cells to Bcl-2 inhibitor, ABT-737, through regulating Mcl-1.
    Wu H; Schiff DS; Lin Y; Neboori HJ; Goyal S; Feng Z; Haffty BG
    Radiat Res; 2014 Dec; 182(6):618-25. PubMed ID: 25409124
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Platinum compounds sensitize ovarian carcinoma cells to ABT-737 by modulation of the Mcl-1/Noxa axis.
    Simonin K; N'Diaye M; Lheureux S; Loussouarn C; Dutoit S; Briand M; Giffard F; Brotin E; Blanc-Fournier C; Poulain L
    Apoptosis; 2013 Apr; 18(4):492-508. PubMed ID: 23344663
    [TBL] [Abstract][Full Text] [Related]  

  • 32. The effects of restraint stress on ceramide metabolism disorders in the rat liver: the role of CerS6 in hepatocyte injury.
    Liu Y; Sun Z; Sun Q; Wang L; Wang C; Li Y; Ma C; Shi W; Zhang G; Dong Y; Zhang X; Cong B
    Lipids Health Dis; 2024 Mar; 23(1):68. PubMed ID: 38431645
    [TBL] [Abstract][Full Text] [Related]  

  • 33. CerS6 Is a Novel Transcriptional Target of p53 Protein Activated by Non-genotoxic Stress.
    Fekry B; Jeffries KA; Esmaeilniakooshkghazi A; Ogretmen B; Krupenko SA; Krupenko NI
    J Biol Chem; 2016 Aug; 291(32):16586-96. PubMed ID: 27302066
    [TBL] [Abstract][Full Text] [Related]  

  • 34. CerS6-Derived Sphingolipids Interact with Mff and Promote Mitochondrial Fragmentation in Obesity.
    Hammerschmidt P; Ostkotte D; Nolte H; Gerl MJ; Jais A; Brunner HL; Sprenger HG; Awazawa M; Nicholls HT; Turpin-Nolan SM; Langer T; Krüger M; Brügger B; Brüning JC
    Cell; 2019 May; 177(6):1536-1552.e23. PubMed ID: 31150623
    [TBL] [Abstract][Full Text] [Related]  

  • 35. ABT-737 induces apoptosis in mantle cell lymphoma cells with a Bcl-2high/Mcl-1low profile and synergizes with other antineoplastic agents.
    Touzeau C; Dousset C; Bodet L; Gomez-Bougie P; Bonnaud S; Moreau A; Moreau P; Pellat-Deceunynck C; Amiot M; Le Gouill S
    Clin Cancer Res; 2011 Sep; 17(18):5973-81. PubMed ID: 21821698
    [TBL] [Abstract][Full Text] [Related]  

  • 36. The Bcl-2/Bcl-XL family inhibitor ABT-737 sensitizes ovarian cancer cells to carboplatin.
    Witham J; Valenti MR; De-Haven-Brandon AK; Vidot S; Eccles SA; Kaye SB; Richardson A
    Clin Cancer Res; 2007 Dec; 13(23):7191-8. PubMed ID: 18056200
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Ceramide synthase 6 mediates sex-specific metabolic response to dietary folic acid in mice.
    Barron K; Ogretmen B; Krupenko N
    J Nutr Biochem; 2021 Dec; 98():108832. PubMed ID: 34358645
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Inhibition of Bcl-2 and Bcl-X enhances chemotherapy sensitivity in hepatoblastoma cells.
    Lieber J; Kirchner B; Eicher C; Warmann SW; Seitz G; Fuchs J; Armeanu-Ebinger S
    Pediatr Blood Cancer; 2010 Dec; 55(6):1089-95. PubMed ID: 20680965
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Selective knockdown of ceramide synthases reveals complex interregulation of sphingolipid metabolism.
    Mullen TD; Spassieva S; Jenkins RW; Kitatani K; Bielawski J; Hannun YA; Obeid LM
    J Lipid Res; 2011 Jan; 52(1):68-77. PubMed ID: 20940143
    [TBL] [Abstract][Full Text] [Related]  

  • 40. AKT1/FOXP3 axis-mediated expression of CerS6 promotes p53 mutant pancreatic tumorigenesis.
    Qi D; Song X; Xue C; Yao W; Shen P; Yu H; Zhang Z
    Cancer Lett; 2021 Dec; 522():105-118. PubMed ID: 34343636
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 12.