207 related articles for article (PubMed ID: 30206422)
1. Anti-TNFR1 targeting in humanized mice ameliorates disease in a model of multiple sclerosis.
Williams SK; Fairless R; Maier O; Liermann PC; Pichi K; Fischer R; Eisel ULM; Kontermann R; Herrmann A; Weksler B; Romero N; Couraud PO; Pfizenmaier K; Diem R
Sci Rep; 2018 Sep; 8(1):13628. PubMed ID: 30206422
[TBL] [Abstract][Full Text] [Related]
2. Co-modulation of TNFR1 and TNFR2 in an animal model of multiple sclerosis.
Fiedler T; Fairless R; Pichi K; Fischer R; Richter F; Kontermann RE; Pfizenmaier K; Diem R; Williams SK
J Neuroinflammation; 2023 Apr; 20(1):100. PubMed ID: 37122019
[TBL] [Abstract][Full Text] [Related]
3. The TNFR1 Antagonist Atrosimab Is Therapeutic in Mouse Models of Acute and Chronic Inflammation.
Richter F; Williams SK; John K; Huber C; Vaslin C; Zanker H; Fairless R; Pichi K; Marhenke S; Vogel A; Dhaen MA; Herrmann S; Herrmann A; Pfizenmaier K; Bantel H; Diem R; Kontermann RE; Fischer R
Front Immunol; 2021; 12():705485. PubMed ID: 34305946
[TBL] [Abstract][Full Text] [Related]
4. Antibody-mediated inhibition of TNFR1 attenuates disease in a mouse model of multiple sclerosis.
Williams SK; Maier O; Fischer R; Fairless R; Hochmeister S; Stojic A; Pick L; Haar D; Musiol S; Storch MK; Pfizenmaier K; Diem R
PLoS One; 2014; 9(2):e90117. PubMed ID: 24587232
[TBL] [Abstract][Full Text] [Related]
5. Targeting pre-ligand assembly domain of TNFR1 ameliorates autoimmune diseases - an unrevealed role in downregulation of Th17 cells.
Wang YL; Chou FC; Chen SJ; Lin SH; Chang DM; Sytwu HK
J Autoimmun; 2011 Nov; 37(3):160-70. PubMed ID: 21689905
[TBL] [Abstract][Full Text] [Related]
6. ATROSAB, a humanized antagonistic anti-tumor necrosis factor receptor one-specific antibody.
Zettlitz KA; Lorenz V; Landauer K; Münkel S; Herrmann A; Scheurich P; Pfizenmaier K; Kontermann R
MAbs; 2010; 2(6):639-47. PubMed ID: 20935477
[TBL] [Abstract][Full Text] [Related]
7. Sequential treatment with a TNFR2 agonist and a TNFR1 antagonist improves outcomes in a humanized mouse model for MS.
Pegoretti V; Bauer J; Fischer R; Paro I; Douwenga W; Kontermann RE; Pfizenmaier K; Houben E; Broux B; Hellings N; Baron W; Laman JD; Eisel ULM
J Neuroinflammation; 2023 May; 20(1):106. PubMed ID: 37138340
[TBL] [Abstract][Full Text] [Related]
8. TNFR1 inhibition with a Nanobody protects against EAE development in mice.
Steeland S; Van Ryckeghem S; Van Imschoot G; De Rycke R; Toussaint W; Vanhoutte L; Vanhove C; De Vos F; Vandenbroucke RE; Libert C
Sci Rep; 2017 Oct; 7(1):13646. PubMed ID: 29057962
[TBL] [Abstract][Full Text] [Related]
9. Antagonistic TNF receptor one-specific antibody (ATROSAB): receptor binding and in vitro bioactivity.
Richter F; Liebig T; Guenzi E; Herrmann A; Scheurich P; Pfizenmaier K; Kontermann RE
PLoS One; 2013; 8(8):e72156. PubMed ID: 23977237
[TBL] [Abstract][Full Text] [Related]
10. Therapeutic effect of PEGylated TNFR1-selective antagonistic mutant TNF in experimental autoimmune encephalomyelitis mice.
Nomura T; Abe Y; Kamada H; Shibata H; Kayamuro H; Inoue M; Kawara T; Arita S; Furuya T; Yamashita T; Nagano K; Yoshikawa T; Yoshioka Y; Mukai Y; Nakagawa S; Taniai M; Ohta T; Serada S; Naka T; Tsunoda S; Tsutsumi Y
J Control Release; 2011 Jan; 149(1):8-14. PubMed ID: 20036293
[TBL] [Abstract][Full Text] [Related]
11. Opposing Functions of Microglial and Macrophagic TNFR2 in the Pathogenesis of Experimental Autoimmune Encephalomyelitis.
Gao H; Danzi MC; Choi CS; Taherian M; Dalby-Hansen C; Ellman DG; Madsen PM; Bixby JL; Lemmon VP; Lambertsen KL; Brambilla R
Cell Rep; 2017 Jan; 18(1):198-212. PubMed ID: 28052249
[TBL] [Abstract][Full Text] [Related]
12. Monovalent TNF receptor 1-selective antibody with improved affinity and neutralizing activity.
Richter F; Zettlitz KA; Seifert O; Herrmann A; Scheurich P; Pfizenmaier K; Kontermann RE
MAbs; 2019 Jan; 11(1):166-177. PubMed ID: 30252601
[TBL] [Abstract][Full Text] [Related]
13. Essential protective role of tumor necrosis factor receptor 2 in neurodegeneration.
Dong Y; Fischer R; Naudé PJ; Maier O; Nyakas C; Duffey M; Van der Zee EA; Dekens D; Douwenga W; Herrmann A; Guenzi E; Kontermann RE; Pfizenmaier K; Eisel UL
Proc Natl Acad Sci U S A; 2016 Oct; 113(43):12304-12309. PubMed ID: 27791020
[TBL] [Abstract][Full Text] [Related]
14. Distinct modes of TNF signaling through its two receptors in health and disease.
Atretkhany KN; Gogoleva VS; Drutskaya MS; Nedospasov SA
J Leukoc Biol; 2020 Jun; 107(6):893-905. PubMed ID: 32083339
[TBL] [Abstract][Full Text] [Related]
15. Pharmacokinetic and Pharmacodynamic Characterisation of an Anti-Mouse TNF Receptor 1 Domain Antibody Formatted for In Vivo Half-Life Extension.
Goodall LJ; Ovecka M; Rycroft D; Friel SL; Sanderson A; Mistry P; Davies ML; Stoop AA
PLoS One; 2015; 10(9):e0137065. PubMed ID: 26352810
[TBL] [Abstract][Full Text] [Related]
16. Structural optimization of a TNFR1-selective antagonistic TNFα mutant to create new-modality TNF-regulating biologics.
Inoue M; Tsuji Y; Yoshimine C; Enomoto S; Morita Y; Osaki N; Kunishige M; Miki M; Amano S; Yamashita K; Kamada H; Tsutsumi Y; Tsunoda SI
J Biol Chem; 2020 Jul; 295(28):9379-9391. PubMed ID: 32398258
[TBL] [Abstract][Full Text] [Related]
17. Generation and characterization of small single domain antibodies inhibiting human tumor necrosis factor receptor 1.
Steeland S; Puimège L; Vandenbroucke RE; Van Hauwermeiren F; Haustraete J; Devoogdt N; Hulpiau P; Leroux-Roels G; Laukens D; Meuleman P; De Vos M; Libert C
J Biol Chem; 2015 Feb; 290(7):4022-37. PubMed ID: 25538244
[TBL] [Abstract][Full Text] [Related]
18. Oligodendroglial TNFR2 Mediates Membrane TNF-Dependent Repair in Experimental Autoimmune Encephalomyelitis by Promoting Oligodendrocyte Differentiation and Remyelination.
Madsen PM; Motti D; Karmally S; Szymkowski DE; Lambertsen KL; Bethea JR; Brambilla R
J Neurosci; 2016 May; 36(18):5128-43. PubMed ID: 27147664
[TBL] [Abstract][Full Text] [Related]
19. Elevated interferon gamma expression in the central nervous system of tumour necrosis factor receptor 1-deficient mice with experimental autoimmune encephalomyelitis.
Wheeler RD; Zehntner SP; Kelly LM; Bourbonnière L; Owens T
Immunology; 2006 Aug; 118(4):527-38. PubMed ID: 16780563
[TBL] [Abstract][Full Text] [Related]
20. A humanized tumor necrosis factor receptor 1 (TNFR1)-specific antagonistic antibody for selective inhibition of tumor necrosis factor (TNF) action.
Kontermann RE; Münkel S; Neumeyer J; Müller D; Branschädel M; Scheurich P; Pfizenmaier K
J Immunother; 2008 Apr; 31(3):225-34. PubMed ID: 18317365
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]