BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

490 related articles for article (PubMed ID: 30207238)

  • 41. Design, synthesis, in vitro antiproliferative activity and apoptosis-inducing studies of 1-(3',4',5'-trimethoxyphenyl)-3-(2'-alkoxycarbonylindolyl)-2-propen-1-one derivatives obtained by a molecular hybridisation approach.
    Preti D; Romagnoli R; Rondanin R; Cacciari B; Hamel E; Balzarini J; Liekens S; Schols D; Estévez-Sarmiento F; Quintana J; Estévez F
    J Enzyme Inhib Med Chem; 2018 Dec; 33(1):1225-1238. PubMed ID: 30141353
    [TBL] [Abstract][Full Text] [Related]  

  • 42. Molecular Modeling, Synthesis and Biological Evaluation of
    Sabbah DA; Hasan SE; Abu Khalaf R; Bardaweel SK; Hajjo R; Alqaisi KM; Sweidan KA; Al-Zuheiri AM
    Molecules; 2020 Nov; 25(22):. PubMed ID: 33207767
    [TBL] [Abstract][Full Text] [Related]  

  • 43. Synthesis and Evaluation of a New Series of Arylidene Indanones as Potential Anticancer Agents.
    Özdemir A; Gökbulut S; Sever B; Çiftçi GA; Altıntop MD
    Anticancer Agents Med Chem; 2018; 18(10):1394-1404. PubMed ID: 29210665
    [TBL] [Abstract][Full Text] [Related]  

  • 44. Synthesis and antitumor activities evaluation of m-(4-morpholinoquinazolin-2-yl)benzamides in vitro and in vivo.
    Wang XM; Xin MH; Xu J; Kang BR; Li Y; Lu SM; Zhang SQ
    Eur J Med Chem; 2015; 96():382-95. PubMed ID: 25911625
    [TBL] [Abstract][Full Text] [Related]  

  • 45. Design, synthesis, biological evaluation and dynamics simulation of indazole derivatives with antiangiogenic and antiproliferative anticancer activity.
    Elsayed NMY; Serya RAT; Tolba MF; Ahmed M; Barakat K; Abou El Ella DA; Abouzid KAM
    Bioorg Chem; 2019 Feb; 82():340-359. PubMed ID: 30428414
    [TBL] [Abstract][Full Text] [Related]  

  • 46. Design, synthesis, biological evaluation, and in silico studies of 2-aminobenzothiazole derivatives as potent PI3Kα inhibitors.
    Haider K; Ahmad K; Najmi AK; Das S; Joseph A; Shahar Yar M
    Arch Pharm (Weinheim); 2022 Oct; 355(10):e2200146. PubMed ID: 35665957
    [TBL] [Abstract][Full Text] [Related]  

  • 47. DW09849, a selective phosphatidylinositol 3-kinase (PI3K) inhibitor, prevents PI3K signaling and preferentially inhibits proliferation of cells containing the oncogenic mutation p110α (H1047R).
    Liu JL; Gao GR; Zhang X; Cao SF; Guo CL; Wang X; Tong LJ; Ding J; Duan WH; Meng LH
    J Pharmacol Exp Ther; 2014 Mar; 348(3):432-41. PubMed ID: 24361696
    [TBL] [Abstract][Full Text] [Related]  

  • 48. Design, synthesis and biological evaluation of novel 4-aminoquinazolines as dual target inhibitors of EGFR-PI3Kα.
    Ding HW; Deng CL; Li DD; Liu DD; Chai SM; Wang W; Zhang Y; Chen K; Li X; Wang J; Song SJ; Song HR
    Eur J Med Chem; 2018 Feb; 146():460-470. PubMed ID: 29407971
    [TBL] [Abstract][Full Text] [Related]  

  • 49. Design, synthesis, in silico and antiproliferative evaluation of novel pyrazole derivatives as VEGFR-2 inhibitors.
    Ravula P; Vamaraju HB; Paturi M; Sharath Chandra JNGN
    Arch Pharm (Weinheim); 2018 Jan; 351(1):. PubMed ID: 29205467
    [TBL] [Abstract][Full Text] [Related]  

  • 50. Design, synthesis and in silico insights of new 7,8-disubstituted-1,3-dimethyl-1H-purine-2,6(3H,7H)-dione derivatives with potent anticancer and multi-kinase inhibitory activities.
    Mohamed AR; El Kerdawy AM; George RF; Georgey HH; Abdel Gawad NM
    Bioorg Chem; 2021 Feb; 107():104569. PubMed ID: 33387732
    [TBL] [Abstract][Full Text] [Related]  

  • 51. Design and synthesis of new RAF kinase-inhibiting antiproliferative quinoline derivatives. Part 2: Diarylurea derivatives.
    El-Gamal MI; Khan MA; Tarazi H; Abdel-Maksoud MS; Gamal El-Din MM; Yoo KH; Oh CH
    Eur J Med Chem; 2017 Feb; 127():413-423. PubMed ID: 28088086
    [TBL] [Abstract][Full Text] [Related]  

  • 52. Synthesis, biological evaluation and structure-activity relationship of a novel class of PI3Kα H1047R mutant inhibitors.
    Zhang N; Yu Z; Yang X; Zhou Y; Wang J; Zhang SL; Wang MW; He Y
    Eur J Med Chem; 2018 Oct; 158():707-719. PubMed ID: 30245395
    [TBL] [Abstract][Full Text] [Related]  

  • 53. Design, synthesis and antiproliferative activity evaluation of m-(4-morpholinyl-1,3,5-triazin-2-yl)benzamides in vitro.
    Wang XM; Xu J; Xin MH; Lu SM; Zhang SQ
    Bioorg Med Chem Lett; 2015 Apr; 25(8):1730-1735. PubMed ID: 25765909
    [TBL] [Abstract][Full Text] [Related]  

  • 54. Design and synthesis of novel 5,6-disubstituted pyridine-2,3-dione-3-thiosemicarbazone derivatives as potential anticancer agents.
    Xie W; Xie S; Zhou Y; Tang X; Liu J; Yang W; Qiu M
    Eur J Med Chem; 2014 Jun; 81():22-7. PubMed ID: 24819956
    [TBL] [Abstract][Full Text] [Related]  

  • 55. New derivatives of sulfonylhydrazone as potential antitumor agents: Design, synthesis and cheminformatics evaluation.
    Sabbah DA; Al-Azaideh BA; Talib WH; Hajjo R; Sweidan K; Al-Zuheiri AM; Sheikha GA; Shraim S
    Acta Pharm; 2021 Dec; 71(4):545-565. PubMed ID: 36651560
    [TBL] [Abstract][Full Text] [Related]  

  • 56. Design, Synthesis, and Biological Evaluation of Substituted Pyrimidines as Potential Phosphatidylinositol 3-Kinase (PI3K) Inhibitors.
    Zhang JQ; Luo YJ; Xiong YS; Yu Y; Tu ZC; Long ZJ; Lai XJ; Chen HX; Luo Y; Weng J; Lu G
    J Med Chem; 2016 Aug; 59(15):7268-74. PubMed ID: 27427973
    [TBL] [Abstract][Full Text] [Related]  

  • 57. Synthesis and biological evaluation of a new series of benzimidazole derivatives as antimicrobial, antiquorum-sensing and antitumor agents.
    El-Gohary NS; Shaaban MI
    Eur J Med Chem; 2017 May; 131():255-262. PubMed ID: 28334654
    [TBL] [Abstract][Full Text] [Related]  

  • 58. Single crystal XRD, DFT investigations and molecular docking study of 2- ((1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)amino)naphthalene-1,4-dione as a potential anti- cancer lead molecule.
    P R KR; Mary YS; Fernandez A; S AP; Mary YS; Thomas R
    Comput Biol Chem; 2019 Feb; 78():153-164. PubMed ID: 30530296
    [TBL] [Abstract][Full Text] [Related]  

  • 59. Design, synthesis, and anti-proliferative activity of 1-(4-methoxyphenyl)-12-hydroxymethyl-p-carborane derivatives.
    Kaise A; Ohta K; Endo Y
    Eur J Med Chem; 2016 Oct; 122():257-263. PubMed ID: 27371927
    [TBL] [Abstract][Full Text] [Related]  

  • 60. Discovery of 2-(2-aminopyrimidin-5-yl)-4-morpholino-N-(pyridin-3-yl)quinazolin-7-amines as novel PI3K/mTOR inhibitors and anticancer agents.
    Peng W; Tu ZC; Long ZJ; Liu Q; Lu G
    Eur J Med Chem; 2016 Jan; 108():644-654. PubMed ID: 26731167
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 25.