BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

345 related articles for article (PubMed ID: 30209118)

  • 1. Transferrin receptor 2 is a potential novel therapeutic target for β-thalassemia: evidence from a murine model.
    Artuso I; Lidonnici MR; Altamura S; Mandelli G; Pettinato M; Muckenthaler MU; Silvestri L; Ferrari G; Camaschella C; Nai A
    Blood; 2018 Nov; 132(21):2286-2297. PubMed ID: 30209118
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Correcting β-thalassemia by combined therapies that restrict iron and modulate erythropoietin activity.
    Casu C; Pettinato M; Liu A; Aghajan M; Lo Presti V; Lidonnici MR; Munoz KA; O'Hara E; Olivari V; Di Modica SM; Booten S; Guo S; Neil G; Miari R; Shapir N; Zafir-Lavie I; Domev H; Ferrari G; Sitara D; Nai A; Rivella S
    Blood; 2020 Oct; 136(17):1968-1979. PubMed ID: 32556142
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Transferrin receptor 2 (Tfr2) genetic deletion makes transfusion-independent a murine model of transfusion-dependent β-thalassemia.
    Di Modica SM; Tanzi E; Olivari V; Lidonnici MR; Pettinato M; Pagani A; Tiboni F; Furiosi V; Silvestri L; Ferrari G; Rivella S; Nai A
    Am J Hematol; 2022 Oct; 97(10):1324-1336. PubMed ID: 36071579
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Bone marrow Tfr2 deletion improves the therapeutic efficacy of the activin-receptor ligand trap RAP-536 in β-thalassemic mice.
    Tanzi E; Di Modica SM; Bordini J; Olivari V; Pagani A; Furiosi V; Silvestri L; Campanella A; Nai A
    Am J Hematol; 2024 Jul; 99(7):1313-1325. PubMed ID: 38629683
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Global loss of Tfr2 with concomitant induced iron deficiency greatly ameliorates the phenotype of a murine thalassemia intermedia model.
    Schmidt PJ; Fitzgerald K; Butler JS; Fleming MD
    Am J Hematol; 2021 Feb; 96(2):251-257. PubMed ID: 33180328
    [TBL] [Abstract][Full Text] [Related]  

  • 6. An RNAi therapeutic targeting Tmprss6 decreases iron overload in Hfe(-/-) mice and ameliorates anemia and iron overload in murine β-thalassemia intermedia.
    Schmidt PJ; Toudjarska I; Sendamarai AK; Racie T; Milstein S; Bettencourt BR; Hettinger J; Bumcrot D; Fleming MD
    Blood; 2013 Feb; 121(7):1200-8. PubMed ID: 23223430
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Extrahepatic deficiency of transferrin receptor 2 is associated with increased erythropoiesis independent of iron overload.
    Wortham AM; Goldman DC; Chen J; Fleming WH; Zhang AS; Enns CA
    J Biol Chem; 2020 Mar; 295(12):3906-3917. PubMed ID: 32054685
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A single approach to targeting transferrin receptor 2 corrects iron and erythropoietic defects in murine models of anemia of inflammation and chronic kidney disease.
    Olivari V; Di Modica SM; Lidonnici MR; Aghajan M; Cordero-Sanchez C; Tanzi E; Pettinato M; Pagani A; Tiboni F; Silvestri L; Guo S; Ferrari G; Nai A
    Kidney Int; 2023 Jul; 104(1):61-73. PubMed ID: 36990212
    [TBL] [Abstract][Full Text] [Related]  

  • 9. mRNA expression of iron regulatory genes in beta-thalassemia intermedia and beta-thalassemia major mouse models.
    Weizer-Stern O; Adamsky K; Amariglio N; Rachmilewitz E; Breda L; Rivella S; Rechavi G
    Am J Hematol; 2006 Jul; 81(7):479-83. PubMed ID: 16755567
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Decreasing TfR1 expression reverses anemia and hepcidin suppression in β-thalassemic mice.
    Li H; Choesang T; Bao W; Chen H; Feola M; Garcia-Santos D; Li J; Sun S; Follenzi A; Pham P; Liu J; Zhang J; Ponka P; An X; Mohandas N; Fleming RE; Rivella S; Li G; Ginzburg YZ
    Blood; 2017 Mar; 129(11):1514-1526. PubMed ID: 28151426
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Deletion of TMPRSS6 attenuates the phenotype in a mouse model of β-thalassemia.
    Nai A; Pagani A; Mandelli G; Lidonnici MR; Silvestri L; Ferrari G; Camaschella C
    Blood; 2012 May; 119(21):5021-9. PubMed ID: 22490684
    [TBL] [Abstract][Full Text] [Related]  

  • 12. New therapeutic targets in transfusion-dependent and -independent thalassemia.
    Cappellini MD; Motta I
    Hematology Am Soc Hematol Educ Program; 2017 Dec; 2017(1):278-283. PubMed ID: 29222267
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The erythroid function of transferrin receptor 2 revealed by Tmprss6 inactivation in different models of transferrin receptor 2 knockout mice.
    Nai A; Pellegrino RM; Rausa M; Pagani A; Boero M; Silvestri L; Saglio G; Roetto A; Camaschella C
    Haematologica; 2014 Jun; 99(6):1016-21. PubMed ID: 24658816
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Inhibition of heme oxygenase ameliorates anemia and reduces iron overload in a β-thalassemia mouse model.
    Garcia-Santos D; Hamdi A; Saxova Z; Fillebeen C; Pantopoulos K; Horvathova M; Ponka P
    Blood; 2018 Jan; 131(2):236-246. PubMed ID: 29180398
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Soluble transferrin receptor as a potential determinant of iron loading in congenital anaemias due to ineffective erythropoiesis.
    Cazzola M; Beguin Y; Bergamaschi G; Guarnone R; Cerani P; Barella S; Cao A; Galanello R
    Br J Haematol; 1999 Sep; 106(3):752-5. PubMed ID: 10468869
    [TBL] [Abstract][Full Text] [Related]  

  • 16. β-Thalassemia intermedia: a comprehensive overview and novel approaches.
    Asadov C; Alimirzoeva Z; Mammadova T; Aliyeva G; Gafarova S; Mammadov J
    Int J Hematol; 2018 Jul; 108(1):5-21. PubMed ID: 29380178
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Hematopoietic deletion of transferrin receptor 2 in mice leads to a block in erythroid differentiation during iron-deficient anemia.
    Rishi G; Secondes ES; Wallace DF; Subramaniam VN
    Am J Hematol; 2016 Aug; 91(8):812-8. PubMed ID: 27169626
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Modified activin receptor IIB ligand trap mitigates ineffective erythropoiesis and disease complications in murine β-thalassemia.
    Suragani RN; Cawley SM; Li R; Wallner S; Alexander MJ; Mulivor AW; Gardenghi S; Rivella S; Grinberg AV; Pearsall RS; Kumar R
    Blood; 2014 Jun; 123(25):3864-72. PubMed ID: 24795345
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A novel murine model of Cooley anemia and its rescue by lentiviral-mediated human beta-globin gene transfer.
    Rivella S; May C; Chadburn A; Rivière I; Sadelain M
    Blood; 2003 Apr; 101(8):2932-9. PubMed ID: 12480689
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Anemia, ineffective erythropoiesis, and hepcidin: interacting factors in abnormal iron metabolism leading to iron overload in β-thalassemia.
    Gardenghi S; Grady RW; Rivella S
    Hematol Oncol Clin North Am; 2010 Dec; 24(6):1089-107. PubMed ID: 21075282
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 18.