140 related articles for article (PubMed ID: 30209480)
1. Mutated variants of squalene-hopene cyclase: enzymatic syntheses of triterpenes bearing oxygen-bridged monocycles and a new 6,6,6,6,6-fusded pentacyclic scaffold, named neogammacerane, from 2,3-oxidosqualene.
Fukuda Y; Watanabe T; Hoshino T
Org Biomol Chem; 2018 Sep; 16(37):8365-8378. PubMed ID: 30209480
[TBL] [Abstract][Full Text] [Related]
2. Alicyclobacillus acidocaldarius Squalene-Hopene Cyclase: The Critical Role of Steric Bulk at Ala306 and the First Enzymatic Synthesis of Epoxydammarane from 2,3-Oxidosqualene.
Ideno N; Umeyama S; Watanabe T; Nakajima M; Sato T; Hoshino T
Chembiochem; 2018 Sep; 19(17):1873-1886. PubMed ID: 29911308
[TBL] [Abstract][Full Text] [Related]
3. Enzymatic syntheses of novel carbocyclic scaffolds with a 6,5 + 5,5 ring system by squalene-hopene cyclase.
Nakano C; Watanabe T; Minamino M; Hoshino T
Org Biomol Chem; 2019 Oct; 17(42):9375-9389. PubMed ID: 31621743
[TBL] [Abstract][Full Text] [Related]
4. Squalene-hopene cyclase: final deprotonation reaction, conformational analysis for the cyclization of (3R,S)-2,3-oxidosqualene and further evidence for the requirement of an isopropylidene moiety both for initiation of the polycyclization cascade and for the formation of the 5-membered E-ring.
Hoshino T; Nakano S; Kondo T; Sato T; Miyoshi A
Org Biomol Chem; 2004 May; 2(10):1456-70. PubMed ID: 15136801
[TBL] [Abstract][Full Text] [Related]
5. Site-directed mutagenesis of squalene-hopene cyclase: altered substrate specificity and product distribution.
Dang T; Prestwich GD
Chem Biol; 2000 Aug; 7(8):643-9. PubMed ID: 11048954
[TBL] [Abstract][Full Text] [Related]
6. Squalene-Hopene Cyclase: Mechanistic Insights into the Polycyclization Cascades of Squalene Analogs Bearing Ethyl and Hydroxymethyl Groups at the C-2 and C-23 Positions.
Kaneko I; Terasawa Y; Hoshino T
Chemistry; 2018 Aug; 24(43):11139-11157. PubMed ID: 29732636
[TBL] [Abstract][Full Text] [Related]
7. Chemo-enzymatic syntheses of drimane-type sesquiterpenes and the fundamental core of hongoquercin meroterpenoid by recombinant squalene-hopene cyclase.
Yonemura Y; Ohyama T; Hoshino T
Org Biomol Chem; 2012 Jan; 10(2):440-6. PubMed ID: 22068606
[TBL] [Abstract][Full Text] [Related]
8. Rationally designed inhibitors as tools for comparing the mechanism of squalene-hopene cyclase with oxidosqualene cyclase.
Viola F; Ceruti M; Cattel L; Milla P; Poralla K; Balliano G
Lipids; 2000 Mar; 35(3):297-303. PubMed ID: 10783007
[TBL] [Abstract][Full Text] [Related]
9. Squalene hopene cyclases and oxido squalene cyclases: potential targets for regulating cyclisation reactions.
Nair IM; Kochupurackal J
Biotechnol Lett; 2023 Jun; 45(5-6):573-588. PubMed ID: 37055654
[TBL] [Abstract][Full Text] [Related]
10. Cyclization of squalene from both termini: identification of an onoceroid synthase and enzymatic synthesis of ambrein.
Ueda D; Hoshino T; Sato T
J Am Chem Soc; 2013 Dec; 135(49):18335-8. PubMed ID: 24274794
[TBL] [Abstract][Full Text] [Related]
11. Reviewing the polyolefin cyclization reaction of the c(35) polyprene catalyzed by squalene-hopene cyclase.
Hoshino T; Kumai Y; Sato T
Chemistry; 2009; 15(9):2091-100. PubMed ID: 19142932
[TBL] [Abstract][Full Text] [Related]
12. Site-directed mutagenesis of putative active-site residues in squalene-hopene cyclase.
Feil C; Süssmuth R; Jung G; Poralla K
Eur J Biochem; 1996 Nov; 242(1):51-5. PubMed ID: 8954152
[TBL] [Abstract][Full Text] [Related]
13. Production of epoxydammaranes by the enzymatic reactions of (3R)- and (3S)-2,3-squalene diols and those of 2,3:22,23-dioxidosqualenes with recombinant squalene cyclase and the mechanistic insight into the polycyclization reactions.
Hoshino T; Yonemura Y; Abe T; Sugino Y
Org Biomol Chem; 2007 Mar; 5(5):792-801. PubMed ID: 17315066
[TBL] [Abstract][Full Text] [Related]
14. β-Amyrin Biosynthesis: The Methyl-30 Group of (3S)-2,3-Oxidosqualene Is More Critical to Its Correct Folding To Generate the Pentacyclic Scaffold than the Methyl-24 Group.
Hoshino T; Miyahara Y; Hanaoka M; Takahashi K; Kaneko I
Chemistry; 2015 Oct; 21(44):15769-84. PubMed ID: 26351084
[TBL] [Abstract][Full Text] [Related]
15. Squalene-hopene cyclases.
Siedenburg G; Jendrossek D
Appl Environ Microbiol; 2011 Jun; 77(12):3905-15. PubMed ID: 21531832
[TBL] [Abstract][Full Text] [Related]
16. Vinyl sulfide derivatives of truncated oxidosqualene as selective inhibitors of oxidosqualene and squalene-hopene cyclases.
Ceruti M; Balliano G; Rocco F; Milla P; Arpicco S; Cattel L; Viola F
Lipids; 2001 Jun; 36(6):629-36. PubMed ID: 11485168
[TBL] [Abstract][Full Text] [Related]
17. Squalene-hopene cyclase from Methylococcus capsulatus (Bath): a bacterium producing hopanoids and steroids.
Tippelt A; Jahnke L; Poralla K
Biochim Biophys Acta; 1998 Mar; 1391(2):223-32. PubMed ID: 9555026
[TBL] [Abstract][Full Text] [Related]
18. Cyclization cascade of the C33-bisnorheptaprenoid catalyzed by recombinant squalene cyclase.
Cheng J; Hoshino T
Org Biomol Chem; 2009 Apr; 7(8):1689-99. PubMed ID: 19343258
[TBL] [Abstract][Full Text] [Related]
19. Arabidopsis thaliana LUP1 converts oxidosqualene to multiple triterpene alcohols and a triterpene diol.
Segura MJ; Meyer MM; Matsuda SP
Org Lett; 2000 Jul; 2(15):2257-9. PubMed ID: 10930257
[TBL] [Abstract][Full Text] [Related]
20. Conjugated methyl sulfide and phenyl sulfide derivatives of oxidosqualene as inhibitors of oxidosqualene and squalene-hopene cyclases.
Rocco F; Bosso SO; Viola F; Milla P; Roma G; Grossi G; Ceruti M
Lipids; 2003 Mar; 38(3):201-7. PubMed ID: 12784859
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]