These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

156 related articles for article (PubMed ID: 30212211)

  • 1. Comparative Studies of the Biosynthetic Gene Clusters for Anthraquinone-Fused Enediynes Shedding Light into the Tailoring Steps of Tiancimycin Biosynthesis.
    Yan X; Chen JJ; Adhikari A; Teijaro CN; Ge H; Crnovcic I; Chang CY; Annaval T; Yang D; Rader C; Shen B
    Org Lett; 2018 Sep; 20(18):5918-5921. PubMed ID: 30212211
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Cytochrome P450 Hydroxylase TnmL Catalyzing Sequential Hydroxylation with an Additional Proofreading Activity in Tiancimycin Biosynthesis.
    Annaval T; Teijaro CN; Adhikari A; Yan X; Chen JJ; Crnovcic I; Yang D; Shen B
    ACS Chem Biol; 2021 Jul; 16(7):1172-1178. PubMed ID: 34138533
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Characterization of an Anthracene Intermediate in Dynemicin Biosynthesis.
    Cohen DR; Townsend CA
    Angew Chem Int Ed Engl; 2018 May; 57(20):5650-5654. PubMed ID: 29512267
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Combinatorial metabolic engineering of Streptomyces sp. CB03234-S for the enhanced production of anthraquinone-fused enediyne tiancimycins.
    Zhuang Z; Kong W; Wen Z; Tong N; Lin J; Zhang F; Fan Z; Yi L; Huang Y; Duan Y; Yan X; Zhu X
    Microb Cell Fact; 2024 May; 23(1):128. PubMed ID: 38704580
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Cofactorless oxygenases guide anthraquinone-fused enediyne biosynthesis.
    Gui C; Kalkreuter E; Liu YC; Li G; Steele AD; Yang D; Chang C; Shen B
    Nat Chem Biol; 2024 Feb; 20(2):243-250. PubMed ID: 37945897
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Resistance to Enediyne Antitumor Antibiotics by Sequestration.
    Chang CY; Yan X; Crnovcic I; Annaval T; Chang C; Nocek B; Rudolf JD; Yang D; Hindra ; Babnigg G; Joachimiak A; Phillips GN; Shen B
    Cell Chem Biol; 2018 Sep; 25(9):1075-1085.e4. PubMed ID: 29937405
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Characterization of TnmH as an
    Adhikari A; Teijaro CN; Yan X; Chang CY; Gui C; Liu YC; Crnovcic I; Yang D; Annaval T; Rader C; Shen B
    J Med Chem; 2020 Aug; 63(15):8432-8441. PubMed ID: 32658465
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Streptomycin-induced ribosome engineering complemented with fermentation optimization for enhanced production of 10-membered enediynes tiancimycin-A and tiancimycin-D.
    Zhuang Z; Jiang C; Zhang F; Huang R; Yi L; Huang Y; Yan X; Duan Y; Zhu X
    Biotechnol Bioeng; 2019 Jun; 116(6):1304-1314. PubMed ID: 30712262
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Genome shuffling based on different types of ribosome engineering mutants for enhanced production of 10-membered enediyne tiancimycin-A.
    Liu H; Jiang C; Lin J; Zhuang Z; Kong W; Liu L; Huang Y; Duan Y; Zhu X
    Appl Microbiol Biotechnol; 2020 May; 104(10):4359-4369. PubMed ID: 32236679
    [TBL] [Abstract][Full Text] [Related]  

  • 10. C-N-Coupled Metabolites Yield Insights into Dynemicin A Biosynthesis.
    Cohen DR; Townsend CA
    Chembiochem; 2020 Aug; 21(15):2137-2142. PubMed ID: 32198800
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Intramolecular C-C Bond Formation Links Anthraquinone and Enediyne Scaffolds in Tiancimycin Biosynthesis.
    Gui C; Kalkreuter E; Liu YC; Adhikari A; Teijaro CN; Yang D; Chang C; Shen B
    J Am Chem Soc; 2022 Nov; 144(44):20452-20462. PubMed ID: 36279548
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A dual role for a polyketide synthase in dynemicin enediyne and anthraquinone biosynthesis.
    Cohen DR; Townsend CA
    Nat Chem; 2018 Feb; 10(2):231-236. PubMed ID: 29359752
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Ribosome engineering and fermentation optimization leads to overproduction of tiancimycin A, a new enediyne natural product from Streptomyces sp. CB03234.
    Liu L; Pan J; Wang Z; Yan X; Yang D; Zhu X; Shen B; Duan Y; Huang Y
    J Ind Microbiol Biotechnol; 2018 Mar; 45(3):141-151. PubMed ID: 29396746
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A discrete intermediate for the biosynthesis of both the enediyne core and the anthraquinone moiety of enediyne natural products.
    Bhardwaj M; Cui Z; Daniel Hankore E; Moonschi FH; Saghaeiannejad Esfahani H; Kalkreuter E; Gui C; Yang D; Phillips GN; Thorson JS; Shen B; Van Lanen SG
    Proc Natl Acad Sci U S A; 2023 Feb; 120(9):e2220468120. PubMed ID: 36802426
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Genome Mining of Micromonospora yangpuensis DSM 45577 as a Producer of an Anthraquinone-Fused Enediyne.
    Yan X; Chen JJ; Adhikari A; Yang D; Crnovcic I; Wang N; Chang CY; Rader C; Shen B
    Org Lett; 2017 Nov; 19(22):6192-6195. PubMed ID: 29086572
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The biosynthetic genes encoding for the production of the dynemicin enediyne core in Micromonospora chersina ATCC53710.
    Gao Q; Thorson JS
    FEMS Microbiol Lett; 2008 May; 282(1):105-14. PubMed ID: 18328078
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Deciphering the pathway-specific regulatory network for production of ten-membered enediyne Tiancimycins in Streptomyces sp. CB03234-S.
    Zhu M; Zhang F; Gan T; Lin J; Duan Y; Zhu X
    Microb Cell Fact; 2022 Sep; 21(1):188. PubMed ID: 36088456
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Submerged fermentation of Streptomyces uncialis providing a biotechnology platform for uncialamycin biosynthesis, engineering, and production.
    Hindra ; Yang D; Luo J; Huang T; Yan X; Adhikari A; Teijaro CN; Ge H; Shen B
    J Ind Microbiol Biotechnol; 2021 Jun; 48(3-4):. PubMed ID: 33739406
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Functional Characterization of Cytochrome P450 Hydroxylase YpmL in Yangpumicin A Biosynthesis and Its Application for Anthraquinone-Fused Enediyne Structural Diversification.
    Yang D; Ye F; Teijaro CN; Hwang D; Annaval T; Adhikari A; Li G; Yan X; Gui C; Rader C; Shen B
    Org Lett; 2022 Feb; 24(5):1219-1223. PubMed ID: 35084871
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The crystal structure of DynF from the dynemicin-biosynthesis pathway of Micromonospora chersina.
    Kosgei AJ; Miller MD; Bhardwaj M; Xu W; Thorson JS; Van Lanen SG; Phillips GN
    Acta Crystallogr F Struct Biol Commun; 2022 Jan; 78(Pt 1):1-7. PubMed ID: 34981769
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.