391 related articles for article (PubMed ID: 30215218)
1. Lack of deuterium isotope effects in the antidepressant effects of (R)-ketamine in a chronic social defeat stress model.
Zhang K; Toki H; Fujita Y; Ma M; Chang L; Qu Y; Harada S; Nemoto T; Mizuno-Yasuhira A; Yamaguchi JI; Chaki S; Hashimoto K
Psychopharmacology (Berl); 2018 Nov; 235(11):3177-3185. PubMed ID: 30215218
[TBL] [Abstract][Full Text] [Related]
2. Lack of metabolism in (R)-ketamine's antidepressant actions in a chronic social defeat stress model.
Zhang K; Fujita Y; Hashimoto K
Sci Rep; 2018 Mar; 8(1):4007. PubMed ID: 29507385
[TBL] [Abstract][Full Text] [Related]
3. Beneficial effects of (R)-ketamine, but not its metabolite (2R,6R)-hydroxynorketamine, in the depression-like phenotype, inflammatory bone markers, and bone mineral density in a chronic social defeat stress model.
Xiong Z; Fujita Y; Zhang K; Pu Y; Chang L; Ma M; Chen J; Hashimoto K
Behav Brain Res; 2019 Aug; 368():111904. PubMed ID: 30980851
[TBL] [Abstract][Full Text] [Related]
4. (S)-norketamine and (2S,6S)-hydroxynorketamine exert potent antidepressant-like effects in a chronic corticosterone-induced mouse model of depression.
Yokoyama R; Higuchi M; Tanabe W; Tsukada S; Naito M; Yamaguchi T; Chen L; Kasai A; Seiriki K; Nakazawa T; Nakagawa S; Hashimoto K; Hashimoto H; Ago Y
Pharmacol Biochem Behav; 2020 Apr; 191():172876. PubMed ID: 32088360
[TBL] [Abstract][Full Text] [Related]
5. (
Zanos P; Highland JN; Stewart BW; Georgiou P; Jenne CE; Lovett J; Morris PJ; Thomas CJ; Moaddel R; Zarate CA; Gould TD
Proc Natl Acad Sci U S A; 2019 Mar; 116(13):6441-6450. PubMed ID: 30867285
[TBL] [Abstract][Full Text] [Related]
6. (R)-Ketamine exerts antidepressant actions partly via conversion to (2R,6R)-hydroxynorketamine, while causing adverse effects at sub-anaesthetic doses.
Zanos P; Highland JN; Liu X; Troppoli TA; Georgiou P; Lovett J; Morris PJ; Stewart BW; Thomas CJ; Thompson SM; Moaddel R; Gould TD
Br J Pharmacol; 2019 Jul; 176(14):2573-2592. PubMed ID: 30941749
[TBL] [Abstract][Full Text] [Related]
7. Activity-dependent brain-derived neurotrophic factor signaling is required for the antidepressant actions of (2
Fukumoto K; Fogaça MV; Liu RJ; Duman C; Kato T; Li XY; Duman RS
Proc Natl Acad Sci U S A; 2019 Jan; 116(1):297-302. PubMed ID: 30559184
[TBL] [Abstract][Full Text] [Related]
8. (2R,6R)-hydroxynorketamine rescues chronic stress-induced depression-like behavior through its actions in the midbrain periaqueductal gray.
Chou D; Peng HY; Lin TB; Lai CY; Hsieh MC; Wen YC; Lee AS; Wang HH; Yang PS; Chen GD; Ho YC
Neuropharmacology; 2018 Sep; 139():1-12. PubMed ID: 29953886
[TBL] [Abstract][Full Text] [Related]
9. Lack of Antidepressant Effects of (2R,6R)-Hydroxynorketamine in a Rat Learned Helplessness Model: Comparison with (R)-Ketamine.
Shirayama Y; Hashimoto K
Int J Neuropsychopharmacol; 2018 Jan; 21(1):84-88. PubMed ID: 29155993
[TBL] [Abstract][Full Text] [Related]
10. (2R,6R)-Hydroxynorketamine is not essential for the antidepressant actions of (R)-ketamine in mice.
Yamaguchi JI; Toki H; Qu Y; Yang C; Koike H; Hashimoto K; Mizuno-Yasuhira A; Chaki S
Neuropsychopharmacology; 2018 Aug; 43(9):1900-1907. PubMed ID: 29802366
[TBL] [Abstract][Full Text] [Related]
11. Pharmacological evaluation of clinically relevant concentrations of (2R,6R)-hydroxynorketamine.
Shaffer CL; Dutra JK; Tseng WC; Weber ML; Bogart LJ; Hales K; Pang J; Volfson D; Am Ende CW; Green ME; Buhl DL
Neuropharmacology; 2019 Jul; 153():73-81. PubMed ID: 31015046
[TBL] [Abstract][Full Text] [Related]
12. Antidepressant-relevant concentrations of the ketamine metabolite (2
Lumsden EW; Troppoli TA; Myers SJ; Zanos P; Aracava Y; Kehr J; Lovett J; Kim S; Wang FH; Schmidt S; Jenne CE; Yuan P; Morris PJ; Thomas CJ; Zarate CA; Moaddel R; Traynelis SF; Pereira EFR; Thompson SM; Albuquerque EX; Gould TD
Proc Natl Acad Sci U S A; 2019 Mar; 116(11):5160-5169. PubMed ID: 30796190
[TBL] [Abstract][Full Text] [Related]
13. Sex-dependent metabolism of ketamine and (
Highland JN; Farmer CA; Zanos P; Lovett J; Zarate CA; Moaddel R; Gould TD
J Psychopharmacol; 2022 Feb; 36(2):170-182. PubMed ID: 34971525
[TBL] [Abstract][Full Text] [Related]
14. Mouse, rat, and dog bioavailability and mouse oral antidepressant efficacy of (
Highland JN; Morris PJ; Zanos P; Lovett J; Ghosh S; Wang AQ; Zarate CA; Thomas CJ; Moaddel R; Gould TD
J Psychopharmacol; 2019 Jan; 33(1):12-24. PubMed ID: 30488740
[TBL] [Abstract][Full Text] [Related]
15. BDNF-TrkB signaling-mediated upregulation of Narp is involved in the antidepressant-like effects of (2R,6R)-hydroxynorketamine in a chronic restraint stress mouse model.
Ju L; Yang J; Zhu T; Liu P; Yang J
BMC Psychiatry; 2022 Mar; 22(1):182. PubMed ID: 35291971
[TBL] [Abstract][Full Text] [Related]
16. Molecular mechanisms of the rapid-acting and long-lasting antidepressant actions of (R)-ketamine.
Hashimoto K
Biochem Pharmacol; 2020 Jul; 177():113935. PubMed ID: 32224141
[TBL] [Abstract][Full Text] [Related]
17. Lack of rapid antidepressant effects of Kir4.1 channel inhibitors in a chronic social defeat stress model: Comparison with (R)-ketamine.
Xiong Z; Zhang K; Ishima T; Ren Q; Ma M; Pu Y; Chang L; Chen J; Hashimoto K
Pharmacol Biochem Behav; 2019 Jan; 176():57-62. PubMed ID: 30502360
[TBL] [Abstract][Full Text] [Related]
18. Brain-derived neurotrophic factor in the ventrolateral periaqueductal gray contributes to (2R,6R)-hydroxynorketamine-mediated actions.
Chou D
Neuropharmacology; 2020 Jun; 170():108068. PubMed ID: 32222405
[TBL] [Abstract][Full Text] [Related]
19. 5-Hydroxytryptamine-Independent Antidepressant Actions of (R)-Ketamine in a Chronic Social Defeat Stress Model.
Zhang K; Dong C; Fujita Y; Fujita A; Hashimoto K
Int J Neuropsychopharmacol; 2018 Feb; 21(2):157-163. PubMed ID: 29155989
[TBL] [Abstract][Full Text] [Related]
20. NMDAR inhibition-independent antidepressant actions of ketamine metabolites.
Zanos P; Moaddel R; Morris PJ; Georgiou P; Fischell J; Elmer GI; Alkondon M; Yuan P; Pribut HJ; Singh NS; Dossou KS; Fang Y; Huang XP; Mayo CL; Wainer IW; Albuquerque EX; Thompson SM; Thomas CJ; Zarate CA; Gould TD
Nature; 2016 May; 533(7604):481-6. PubMed ID: 27144355
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
