197 related articles for article (PubMed ID: 30217986)
1. AAV serotype 8-mediated liver specific GNMT expression delays progression of hepatocellular carcinoma and prevents carbon tetrachloride-induced liver damage.
Fang CC; Wu CF; Liao YJ; Huang SF; Chen M; Chen YA
Sci Rep; 2018 Sep; 8(1):13802. PubMed ID: 30217986
[TBL] [Abstract][Full Text] [Related]
2. Loss of the glycine N-methyltransferase gene leads to steatosis and hepatocellular carcinoma in mice.
Martínez-Chantar ML; Vázquez-Chantada M; Ariz U; Martínez N; Varela M; Luka Z; Capdevila A; Rodríguez J; Aransay AM; Matthiesen R; Yang H; Calvisi DF; Esteller M; Fraga M; Lu SC; Wagner C; Mato JM
Hepatology; 2008 Apr; 47(4):1191-9. PubMed ID: 18318442
[TBL] [Abstract][Full Text] [Related]
3. Induction of GNMT by 1,2,3,4,6-penta-O-galloyl-beta-D-glucopyranoside through proteasome-independent MYC downregulation in hepatocellular carcinoma.
Kant R; Yen CH; Hung JH; Lu CK; Tung CY; Chang PC; Chen YH; Tyan YC; Chen YA
Sci Rep; 2019 Feb; 9(1):1968. PubMed ID: 30760754
[TBL] [Abstract][Full Text] [Related]
4. Characterization of the GNMT-HectH9-PREX2 tripartite relationship in the pathogenesis of hepatocellular carcinoma.
Li CH; Yen CH; Chen YF; Lee KJ; Fang CC; Zhang X; Lai CC; Huang SF; Lin HK; Arthur Chen YM
Int J Cancer; 2017 May; 140(10):2284-2297. PubMed ID: 28205209
[TBL] [Abstract][Full Text] [Related]
5. A DNA methylation signature associated with the epigenetic repression of glycine N-methyltransferase in human hepatocellular carcinoma.
Huidobro C; Toraño EG; Fernández AF; Urdinguio RG; Rodríguez RM; Ferrero C; Martínez-Camblor P; Boix L; Bruix J; García-Rodríguez JL; Varela-Rey M; Mato JM; Martínez-Chantar ML; Fraga MF
J Mol Med (Berl); 2013 Aug; 91(8):939-50. PubMed ID: 23475283
[TBL] [Abstract][Full Text] [Related]
6. Gene Expression and DNA Methylation Alterations in the Glycine N-Methyltransferase Gene in Diet-Induced Nonalcoholic Fatty Liver Disease-Associated Carcinogenesis.
Borowa-Mazgaj B; de Conti A; Tryndyak V; Steward CR; Jimenez L; Melnyk S; Seneshaw M; Mirshahi F; Rusyn I; Beland FA; Sanyal AJ; Pogribny IP
Toxicol Sci; 2019 Aug; 170(2):273-282. PubMed ID: 31086990
[TBL] [Abstract][Full Text] [Related]
7. MicroRNA-224 down-regulates Glycine N-methyltransferase gene expression in Hepatocellular Carcinoma.
Hung JH; Li CH; Yeh CH; Huang PC; Fang CC; Chen YF; Lee KJ; Chou CH; Cheng HY; Huang HD; Chen M; Tsai TF; Lin AM; Yen CH; Tsou AP; Tyan YC; Chen YA
Sci Rep; 2018 Aug; 8(1):12284. PubMed ID: 30115977
[TBL] [Abstract][Full Text] [Related]
8. Hepatoma cells from mice deficient in glycine N-methyltransferase have increased RAS signaling and activation of liver kinase B1.
Martínez-López N; García-Rodríguez JL; Varela-Rey M; Gutiérrez V; Fernández-Ramos D; Beraza N; Aransay AM; Schlangen K; Lozano JJ; Aspichueta P; Luka Z; Wagner C; Evert M; Calvisi DF; Lu SC; Mato JM; Martínez-Chantar ML
Gastroenterology; 2012 Sep; 143(3):787-798.e13. PubMed ID: 22687285
[TBL] [Abstract][Full Text] [Related]
9. Downregulation of Methionine Cycle Genes
Chen PM; Tsai CH; Huang CC; Hwang HH; Li JR; Liu CC; Ko HA; Chiang EI
Int J Mol Sci; 2022 Jan; 23(1):. PubMed ID: 35008908
[TBL] [Abstract][Full Text] [Related]
10. A novel role of the tumor suppressor GNMT in cellular defense against DNA damage.
Wang YC; Lin WL; Lin YJ; Tang FY; Chen YM; Chiang EP
Int J Cancer; 2014 Feb; 134(4):799-810. PubMed ID: 23922098
[TBL] [Abstract][Full Text] [Related]
11. MiR-873-5p acts as an epigenetic regulator in early stages of liver fibrosis and cirrhosis.
Fernández-Ramos D; Fernández-Tussy P; Lopitz-Otsoa F; Gutiérrez-de-Juan V; Navasa N; Barbier-Torres L; Zubiete-Franco I; Simón J; Fernández AF; Arbelaiz A; Aransay AM; Lavín JL; Beraza N; Perugorria MJ; Banales JM; Villa E; Fraga MF; Anguita J; Avila MA; Berasain C; Iruzibieta P; Crespo J; Lu SC; Varela-Rey M; Mato JM; Delgado TC; Martínez-Chantar ML
Cell Death Dis; 2018 Sep; 9(10):958. PubMed ID: 30237481
[TBL] [Abstract][Full Text] [Related]
12. Characterization of a glycine N-methyltransferase gene knockout mouse model for hepatocellular carcinoma: Implications of the gender disparity in liver cancer susceptibility.
Liao YJ; Liu SP; Lee CM; Yen CH; Chuang PC; Chen CY; Tsai TF; Huang SF; Lee YH; Chen YM
Int J Cancer; 2009 Feb; 124(4):816-26. PubMed ID: 19035462
[TBL] [Abstract][Full Text] [Related]
13. Identification of 1,2,3,4,6-Penta-O-galloyl-β-d-glucopyranoside as a Glycine N-Methyltransferase Enhancer by High-Throughput Screening of Natural Products Inhibits Hepatocellular Carcinoma.
Kant R; Yen CH; Lu CK; Lin YC; Li JH; Chen YM
Int J Mol Sci; 2016 May; 17(5):. PubMed ID: 27153064
[TBL] [Abstract][Full Text] [Related]
14. Tumor suppressor gene glycine N-methyltransferase and its potential in liver disorders and hepatocellular carcinoma.
Chen M; Yang MH; Chang MM; Tyan YC; Chen YA
Toxicol Appl Pharmacol; 2019 Sep; 378():114607. PubMed ID: 31170416
[TBL] [Abstract][Full Text] [Related]
15. Dysregulated transmethylation leading to hepatocellular carcinoma compromises redox homeostasis and glucose formation.
Hughey CC; James FD; Wang Z; Goelzer M; Wasserman DH
Mol Metab; 2019 May; 23():1-13. PubMed ID: 30850319
[TBL] [Abstract][Full Text] [Related]
16. Inhibition of natural killer cells protects the liver against acute injury in the absence of glycine N-methyltransferase.
Gomez-Santos L; Luka Z; Wagner C; Fernandez-Alvarez S; Lu SC; Mato JM; Martinez-Chantar ML; Beraza N
Hepatology; 2012 Aug; 56(2):747-59. PubMed ID: 22392635
[TBL] [Abstract][Full Text] [Related]
17. Discovery of an Orally Efficacious MYC Inhibitor for Liver Cancer Using a GNMT-Based High-Throughput Screening System and Structure-Activity Relationship Analysis.
Kant R; Yang MH; Tseng CH; Yen CH; Li WY; Tyan YC; Chen M; Tzeng CC; Chen WC; You K; Wang WC; Chen YL; Chen YA
J Med Chem; 2021 Jul; 64(13):8992-9009. PubMed ID: 34132534
[TBL] [Abstract][Full Text] [Related]
18. Preferential targeting of disseminated liver tumors using a recombinant adeno-associated viral vector.
Della Peruta M; Badar A; Rosales C; Chokshi S; Kia A; Nathwani D; Galante E; Yan R; Arstad E; Davidoff AM; Williams R; Lythgoe MF; Nathwani AC
Hum Gene Ther; 2015 Feb; 26(2):94-103. PubMed ID: 25569358
[TBL] [Abstract][Full Text] [Related]
19. Functional characterization of glycine N-methyltransferase and its interactive protein DEPDC6/DEPTOR in hepatocellular carcinoma.
Yen CH; Lu YC; Li CH; Lee CM; Chen CY; Cheng MY; Huang SF; Chen KF; Cheng AL; Liao LY; Lee YH; Chen YM
Mol Med; 2012 Mar; 18(1):286-96. PubMed ID: 22160218
[TBL] [Abstract][Full Text] [Related]
20. Blocking sphingosine 1-phosphate receptor 2 accelerates hepatocellular carcinoma progression in a mouse model of NASH.
Yoshida T; Tsuchiya A; Kumagai M; Takeuchi S; Nojiri S; Watanabe T; Ogawa M; Itoh M; Takamura M; Suganami T; Ogawa Y; Terai S
Biochem Biophys Res Commun; 2020 Oct; 530(4):665-672. PubMed ID: 32768187
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]