BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

141 related articles for article (PubMed ID: 30221038)

  • 1. Evolution of melanoma cross-resistance to CD8
    Pieper N; Zaremba A; Leonardelli S; Harbers FN; Schwamborn M; Lübcke S; Schrörs B; Baingo J; Schramm A; Haferkamp S; Seifert U; Sucker A; Lennerz V; Wölfel T; Schadendorf D; Schilling B; Paschen A; Zhao F
    Oncoimmunology; 2018; 7(8):e1450127. PubMed ID: 30221038
    [TBL] [Abstract][Full Text] [Related]  

  • 2. PD-L1 Expression and Tumor-Infiltrating Lymphocytes Define Different Subsets of MAPK Inhibitor-Treated Melanoma Patients.
    Kakavand H; Wilmott JS; Menzies AM; Vilain R; Haydu LE; Yearley JH; Thompson JF; Kefford RF; Hersey P; Long GV; Scolyer RA
    Clin Cancer Res; 2015 Jul; 21(14):3140-8. PubMed ID: 25609064
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Melanoma Differentiation Trajectories Determine Sensitivity toward Pre-Existing CD8
    Harbers FN; Thier B; Stupia S; Zhu S; Schwamborn M; Peller V; Chauvistré H; Crivello P; Fleischhauer K; Roesch A; Sucker A; Schadendorf D; Chen Y; Paschen A; Zhao F
    J Invest Dermatol; 2021 Oct; 141(10):2480-2489. PubMed ID: 33798535
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Clinical, Molecular, and Immune Analysis of Dabrafenib-Trametinib Combination Treatment for BRAF Inhibitor-Refractory Metastatic Melanoma: A Phase 2 Clinical Trial.
    Chen G; McQuade JL; Panka DJ; Hudgens CW; Amin-Mansour A; Mu XJ; Bahl S; Jané-Valbuena J; Wani KM; Reuben A; Creasy CA; Jiang H; Cooper ZA; Roszik J; Bassett RL; Joon AY; Simpson LM; Mouton RD; Glitza IC; Patel SP; Hwu WJ; Amaria RN; Diab A; Hwu P; Lazar AJ; Wargo JA; Garraway LA; Tetzlaff MT; Sullivan RJ; Kim KB; Davies MA
    JAMA Oncol; 2016 Aug; 2(8):1056-64. PubMed ID: 27124486
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The activation of MAPK in melanoma cells resistant to BRAF inhibition promotes PD-L1 expression that is reversible by MEK and PI3K inhibition.
    Jiang X; Zhou J; Giobbie-Hurder A; Wargo J; Hodi FS
    Clin Cancer Res; 2013 Feb; 19(3):598-609. PubMed ID: 23095323
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Vemurafenib resistance reprograms melanoma cells towards glutamine dependence.
    Hernandez-Davies JE; Tran TQ; Reid MA; Rosales KR; Lowman XH; Pan M; Moriceau G; Yang Y; Wu J; Lo RS; Kong M
    J Transl Med; 2015 Jul; 13():210. PubMed ID: 26139106
    [TBL] [Abstract][Full Text] [Related]  

  • 7. BRAF inhibition is associated with increased clonality in tumor-infiltrating lymphocytes.
    Cooper ZA; Frederick DT; Juneja VR; Sullivan RJ; Lawrence DP; Piris A; Sharpe AH; Fisher DE; Flaherty KT; Wargo JA
    Oncoimmunology; 2013 Oct; 2(10):e26615. PubMed ID: 24251082
    [TBL] [Abstract][Full Text] [Related]  

  • 8. BRAF Targeting Sensitizes Resistant Melanoma to Cytotoxic T Cells.
    Atay C; Kwak T; Lavilla-Alonso S; Donthireddy L; Richards A; Moberg V; Pilon-Thomas S; Schell M; Messina JL; Rebecca VW; Xiao M; Tan J; Zhang G; Weber JS; Herlyn M; Sarnaik AA; Gabrilovich DI
    Clin Cancer Res; 2019 May; 25(9):2783-2794. PubMed ID: 30765391
    [TBL] [Abstract][Full Text] [Related]  

  • 9. BRAF and MEK Inhibitors Influence the Function of Reprogrammed T Cells: Consequences for Adoptive T-Cell Therapy.
    Dörrie J; Babalija L; Hoyer S; Gerer KF; Schuler G; Heinzerling L; Schaft N
    Int J Mol Sci; 2018 Jan; 19(1):. PubMed ID: 29346301
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A TLR7 agonist strengthens T and NK cell function during BRAF-targeted therapy in a preclinical melanoma model.
    Bellmann L; Cappellano G; Schachtl-Riess JF; Prokopi A; Seretis A; Ortner D; Tripp CH; Brinckerhoff CE; Mullins DW; Stoitzner P
    Int J Cancer; 2020 Mar; 146(5):1409-1420. PubMed ID: 31702822
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Targeting the PI3K/AKT/mTOR pathway overcomes the stimulating effect of dabrafenib on the invasive behavior of melanoma cells with acquired resistance to the BRAF inhibitor.
    Caporali S; Alvino E; Lacal PM; Levati L; Giurato G; Memoli D; Caprini E; Antonini Cappellini GC; D'Atri S
    Int J Oncol; 2016 Sep; 49(3):1164-74. PubMed ID: 27572607
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Anaplastic Lymphoma Kinase Confers Resistance to BRAF Kinase Inhibitors in Melanoma.
    Janostiak R; Malvi P; Wajapeyee N
    iScience; 2019 Jun; 16():453-467. PubMed ID: 31229894
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Recurrent Tumor Cell-Intrinsic and -Extrinsic Alterations during MAPKi-Induced Melanoma Regression and Early Adaptation.
    Song C; Piva M; Sun L; Hong A; Moriceau G; Kong X; Zhang H; Lomeli S; Qian J; Yu CC; Damoiseaux R; Kelley MC; Dahlman KB; Scumpia PO; Sosman JA; Johnson DB; Ribas A; Hugo W; Lo RS
    Cancer Discov; 2017 Nov; 7(11):1248-1265. PubMed ID: 28864476
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Immunomodulatory effects of BRAF and MEK inhibitors: Implications for Melanoma therapy.
    Kuske M; Westphal D; Wehner R; Schmitz M; Beissert S; Praetorius C; Meier F
    Pharmacol Res; 2018 Oct; 136():151-159. PubMed ID: 30145328
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Innate immune receptor signaling induces transient melanoma dedifferentiation while preserving immunogenicity.
    Thier B; Zhao F; Stupia S; Brüggemann A; Koch J; Schulze N; Horn S; Coch C; Hartmann G; Sucker A; Schadendorf D; Paschen A
    J Immunother Cancer; 2022 Jun; 10(6):. PubMed ID: 35697379
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Upstream mitogen-activated protein kinase (MAPK) pathway inhibition: MEK inhibitor followed by a BRAF inhibitor in advanced melanoma patients.
    Goldinger SM; Zimmer L; Schulz C; Ugurel S; Hoeller C; Kaehler KC; Schadendorf D; Hassel JC; Becker J; Hauschild A; Dummer R;
    Eur J Cancer; 2014 Jan; 50(2):406-10. PubMed ID: 24183461
    [TBL] [Abstract][Full Text] [Related]  

  • 17. ER Translocation of the MAPK Pathway Drives Therapy Resistance in BRAF-Mutant Melanoma.
    Ojha R; Leli NM; Onorati A; Piao S; Verginadis II; Tameire F; Rebecca VW; Chude CI; Murugan S; Fennelly C; Noguera-Ortega E; Chu CT; Liu S; Xu X; Krepler C; Xiao M; Xu W; Wei Z; Frederick DT; Boland G; Mitchell TC; Karakousis GC; Schuchter LM; Flaherty KT; Zhang G; Herlyn M; Koumenis C; Amaravadi RK
    Cancer Discov; 2019 Mar; 9(3):396-415. PubMed ID: 30563872
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Glucose metabolism and NRF2 coordinate the antioxidant response in melanoma resistant to MAPK inhibitors.
    Khamari R; Trinh A; Gabert PE; Corazao-Rozas P; Riveros-Cruz S; Balayssac S; Malet-Martino M; Dekiouk S; Joncquel Chevalier Curt M; Maboudou P; Garçon G; Ravasi L; Guerreschi P; Mortier L; Quesnel B; Marchetti P; Kluza J
    Cell Death Dis; 2018 Feb; 9(3):325. PubMed ID: 29487283
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Progression patterns under BRAF inhibitor treatment and treatment beyond progression in patients with metastatic melanoma.
    Hassel JC; Buder-Bakhaya K; Bender C; Zimmer L; Weide B; Loquai C; Ugurel S; Slynko A; Gutzmer R;
    Cancer Med; 2018 Jan; 7(1):95-104. PubMed ID: 29266761
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Kinase inhibitor library screening identifies synergistic drug combinations effective in sensitive and resistant melanoma cells.
    Margue C; Philippidou D; Kozar I; Cesi G; Felten P; Kulms D; Letellier E; Haan C; Kreis S
    J Exp Clin Cancer Res; 2019 Feb; 38(1):56. PubMed ID: 30728057
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.