249 related articles for article (PubMed ID: 30224054)
1. Molecular Determinants of Substrate Affinity and Enzyme Activity of a Cytochrome P450
Geronimo I; Denning CA; Heidary DK; Glazer EC; Payne CM
Biophys J; 2018 Oct; 115(7):1251-1263. PubMed ID: 30224054
[TBL] [Abstract][Full Text] [Related]
2. Effect of Mutation and Substrate Binding on the Stability of Cytochrome P450BM3 Variants.
Geronimo I; Denning CA; Rogers WE; Othman T; Huxford T; Heidary DK; Glazer EC; Payne CM
Biochemistry; 2016 Jun; 55(25):3594-606. PubMed ID: 27267136
[TBL] [Abstract][Full Text] [Related]
3. Hoodwinking Cytochrome P450BM3 into Hydroxylating Non-Native Substrates by Exploiting Its Substrate Misrecognition.
Shoji O; Aiba Y; Watanabe Y
Acc Chem Res; 2019 Apr; 52(4):925-934. PubMed ID: 30888147
[TBL] [Abstract][Full Text] [Related]
4. Novel haem co-ordination variants of flavocytochrome P450BM3.
Girvan HM; Toogood HS; Littleford RE; Seward HE; Smith WE; Ekanem IS; Leys D; Cheesman MR; Munro AW
Biochem J; 2009 Jan; 417(1):65-76. PubMed ID: 18721129
[TBL] [Abstract][Full Text] [Related]
5. Exploring PTDH-P450BM3 Variants for the Synthesis of Drug Metabolites.
Beyer N; Kulig JK; Fraaije MW; Hayes MA; Janssen DB
Chembiochem; 2018 Feb; 19(4):326-337. PubMed ID: 29181885
[TBL] [Abstract][Full Text] [Related]
6. P450
Beyer N; Kulig JK; Bartsch A; Hayes MA; Janssen DB; Fraaije MW
Appl Microbiol Biotechnol; 2017 Mar; 101(6):2319-2331. PubMed ID: 27900443
[TBL] [Abstract][Full Text] [Related]
7. Expanding the applicability of cytochrome P450s and other haemoproteins.
Ariyasu S; Stanfield JK; Aiba Y; Shoji O
Curr Opin Chem Biol; 2020 Dec; 59():155-163. PubMed ID: 32781431
[TBL] [Abstract][Full Text] [Related]
8. A highly active single-mutation variant of P450BM3 (CYP102A1).
Whitehouse CJ; Bell SG; Yang W; Yorke JA; Blanford CF; Strong AJ; Morse EJ; Bartlam M; Rao Z; Wong LL
Chembiochem; 2009 Jul; 10(10):1654-6. PubMed ID: 19492389
[TBL] [Abstract][Full Text] [Related]
9. Functional interactions in cytochrome P450BM3. Fatty acid substrate binding alters electron-transfer properties of the flavoprotein domain.
Murataliev MB; Feyereisen R
Biochemistry; 1996 Nov; 35(47):15029-37. PubMed ID: 8942669
[TBL] [Abstract][Full Text] [Related]
10. Filling a hole in cytochrome P450 BM3 improves substrate binding and catalytic efficiency.
Huang WC; Westlake AC; Maréchal JD; Joyce MG; Moody PC; Roberts GC
J Mol Biol; 2007 Oct; 373(3):633-51. PubMed ID: 17868686
[TBL] [Abstract][Full Text] [Related]
11. Cytochrome P450-The Wonderful Nanomachine Revealed through Dynamic Simulations of the Catalytic Cycle.
Dubey KD; Shaik S
Acc Chem Res; 2019 Feb; 52(2):389-399. PubMed ID: 30633519
[TBL] [Abstract][Full Text] [Related]
12. Improving the activity of cytochrome P450 BM-3 catalyzing indole hydroxylation by directed evolution.
Pengpai Z; Sheng H; Lehe M; Yinlin L; Zhihua J; Guixiang H
Appl Biochem Biotechnol; 2013 Sep; 171(1):93-103. PubMed ID: 23817788
[TBL] [Abstract][Full Text] [Related]
13. Insights into an efficient light-driven hybrid P450 BM3 enzyme from crystallographic, spectroscopic and biochemical studies.
Spradlin J; Lee D; Mahadevan S; Mahomed M; Tang L; Lam Q; Colbert A; Shafaat OS; Goodin D; Kloos M; Kato M; Cheruzel LE
Biochim Biophys Acta; 2016 Dec; 1864(12):1732-1738. PubMed ID: 27639964
[TBL] [Abstract][Full Text] [Related]
14. Insights into electron leakage in the reaction cycle of cytochrome P450 BM3 revealed by kinetic modeling and mutagenesis.
Lim JB; Barker KA; Eller KA; Jiang L; Molina V; Saifee JF; Sikes HD
Protein Sci; 2015 Nov; 24(11):1874-83. PubMed ID: 26311413
[TBL] [Abstract][Full Text] [Related]
15. Free energy calculations give insight into the stereoselective hydroxylation of α-ionones by engineered cytochrome P450 BM3 mutants.
de Beer SB; Venkataraman H; Geerke DP; Oostenbrink C; Vermeulen NP
J Chem Inf Model; 2012 Aug; 52(8):2139-48. PubMed ID: 22765880
[TBL] [Abstract][Full Text] [Related]
16. Functional interactions in cytochrome P450BM3: flavin semiquinone intermediates, role of NADP(H), and mechanism of electron transfer by the flavoprotein domain.
Murataliev MB; Klein M; Fulco A; Feyereisen R
Biochemistry; 1997 Jul; 36(27):8401-12. PubMed ID: 9204888
[TBL] [Abstract][Full Text] [Related]
17. Structural analysis of Cytochrome P450 BM3 mutant M11 in complex with dithiothreitol.
Frydenvang K; Verkade-Vreeker MCA; Dohmen F; Commandeur JNM; Rafiq M; Mirza O; Jørgensen FS; Geerke DP
PLoS One; 2019; 14(5):e0217292. PubMed ID: 31125381
[TBL] [Abstract][Full Text] [Related]
18. Hydroxylation of anilides by engineered cytochrome P450
O'Hanlon JA; Ren X; Morris M; Wong LL; Robertson J
Org Biomol Chem; 2017 Oct; 15(41):8780-8787. PubMed ID: 29019509
[TBL] [Abstract][Full Text] [Related]
19. Engineering bacterial cytochrome P450 (P450) BM3 into a prototype with human P450 enzyme activity using indigo formation.
Park SH; Kim DH; Kim D; Kim DH; Jung HC; Pan JG; Ahn T; Kim D; Yun CH
Drug Metab Dispos; 2010 May; 38(5):732-9. PubMed ID: 20100815
[TBL] [Abstract][Full Text] [Related]
20. Molecular Dynamics and QM/MM Calculations Predict the Substrate-Induced Gating of Cytochrome P450 BM3 and the Regio- and Stereoselectivity of Fatty Acid Hydroxylation.
Dubey KD; Wang B; Shaik S
J Am Chem Soc; 2016 Jan; 138(3):837-45. PubMed ID: 26716578
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]