BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

143 related articles for article (PubMed ID: 30227243)

  • 1. The dual sex hormone specificity for human reductive 17β-hydroxysteroid dehydrogenase type 7: Synergistic function in estrogen and androgen control.
    Thériault JF; Lin SX
    J Steroid Biochem Mol Biol; 2019 Feb; 186():61-65. PubMed ID: 30227243
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synergistic control of sex hormones by 17β-HSD type 7: a novel target for estrogen-dependent breast cancer.
    Wang X; Gérard C; Thériault JF; Poirier D; Doillon CJ; Lin SX
    J Mol Cell Biol; 2015 Dec; 7(6):568-79. PubMed ID: 25966904
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Substrate inhibition of 17β-HSD1 in living cells and regulation of 17β-HSD7 by 17β-HSD1 knockdown.
    Han H; Thériault JF; Chen G; Lin SX
    J Steroid Biochem Mol Biol; 2017 Sep; 172():36-45. PubMed ID: 28554725
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Cloning and characterization of human form 2 type 7 17beta-hydroxysteroid dehydrogenase, a primarily 3beta-keto reductase and estrogen activating and androgen inactivating enzyme.
    Liu H; Robert A; Luu-The V
    J Steroid Biochem Mol Biol; 2005 Feb; 94(1-3):173-9. PubMed ID: 15862963
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Human oestrogenic 17beta-hydroxysteroid dehydrogenase specificity: enzyme regulation through an NADPH-dependent substrate inhibition towards the highly specific oestrone reduction.
    Gangloff A; Garneau A; Huang YW; Yang F; Lin SX
    Biochem J; 2001 May; 356(Pt 1):269-76. PubMed ID: 11336660
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Potent and selective steroidal inhibitors of 17beta-hydroxysteroid dehydrogenase type 7, an enzyme that catalyzes the reduction of the key hormones estrone and dihydrotestosterone.
    Bellavance E; Luu-The V; Poirier D
    J Med Chem; 2009 Dec; 52(23):7488-502. PubMed ID: 19772289
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Reductive 17beta-hydroxysteroid dehydrogenases which synthesize estradiol and inactivate dihydrotestosterone constitute major and concerted players in ER+ breast cancer cells.
    Zhang CY; Wang WQ; Chen J; Lin SX
    J Steroid Biochem Mol Biol; 2015 Jun; 150():24-34. PubMed ID: 25257817
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mutual regulations and breast cancer cell control by steroidogenic enzymes: Dual sex-hormone receptor modulation upon 17β-HSD7 inhibition.
    Sang X; Han H; Li T; Lin SX
    J Steroid Biochem Mol Biol; 2019 Oct; 193():105411. PubMed ID: 31207361
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Estrogen and androgen-converting enzymes 17β-hydroxysteroid dehydrogenase and their involvement in cancer: with a special focus on 17β-hydroxysteroid dehydrogenase type 1, 2, and breast cancer.
    Hilborn E; Stål O; Jansson A
    Oncotarget; 2017 May; 8(18):30552-30562. PubMed ID: 28430630
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Mimicking postmenopausal steroid metabolism in breast cancer cell culture: Differences in response to DHEA or other steroids as hormone sources.
    Xu D; Lin SX
    J Steroid Biochem Mol Biol; 2016 Jul; 161():92-100. PubMed ID: 26200948
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Crystal structures of human 17β-hydroxysteroid dehydrogenase type 1 complexed with estrone and NADP
    Li T; Stephen P; Zhu DW; Shi R; Lin SX
    FEBS J; 2019 Jun; 286(11):2155-2166. PubMed ID: 30768851
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Human estrogenic 17beta-hydroxysteroid dehydrogenase: predominance of estrone reduction and its induction by NADPH.
    Jin JZ; Lin SX
    Biochem Biophys Res Commun; 1999 Jun; 259(2):489-93. PubMed ID: 10362535
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Inhibition of 17beta-hydroxysteroid dehydrogenase type 7 modulates breast cancer protein profile and enhances apoptosis by down-regulating GRP78.
    Wang XQ; Aka JA; Li T; Xu D; Doillon CJ; Lin SX
    J Steroid Biochem Mol Biol; 2017 Sep; 172():188-197. PubMed ID: 28645527
    [TBL] [Abstract][Full Text] [Related]  

  • 14. 17beta-hydroxysteroid dehydrogenase type 1 stimulates breast cancer by dihydrotestosterone inactivation in addition to estradiol production.
    Aka JA; Mazumdar M; Chen CQ; Poirier D; Lin SX
    Mol Endocrinol; 2010 Apr; 24(4):832-45. PubMed ID: 20172961
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The multi-specific human 17 beta-hydroxysteroid dehydrogenase type 7: Non-competitive inhibitors can target different catalyses to facilitate breast cancer treatment.
    Thériault JF; Poirier D; Lin SX
    J Steroid Biochem Mol Biol; 2021 Nov; 214():105963. PubMed ID: 34400276
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Reductive 17beta-hydroxysteroid dehydrogenases in the sulfatase pathway: critical in the cell proliferation of breast cancer.
    Aka JA; Mazumdar M; Lin SX
    Mol Cell Endocrinol; 2009 Mar; 301(1-2):183-90. PubMed ID: 19038308
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Androgen receptor-mediated stimulation of 17 beta-hydroxysteroid dehydrogenase activity by dihydrotestosterone and medroxyprogesterone acetate in ZR-75-1 human breast cancer cells.
    Couture P; Thériault C; Simard J; Labrie F
    Endocrinology; 1993 Jan; 132(1):179-85. PubMed ID: 8380373
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Alterations in luteal production of androstenedione, testosterone, and estrone, but not estradiol, during mid- and late pregnancy in pigs: effects of androgen deficiency.
    Grzesiak M; Knapczyk-Stwora K; Ciereszko RE; Wieciech I; Slomczynska M
    Theriogenology; 2014 Sep; 82(5):720-33. PubMed ID: 25011982
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A challenge for medicinal chemistry by the 17β-hydroxysteroid dehydrogenase superfamily: an integrated biological function and inhibition study.
    Lin SX; Poirier D; Adamski J
    Curr Top Med Chem; 2013; 13(10):1164-71. PubMed ID: 23647539
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Androgen inactivation and steroid-converting enzyme expression in abdominal adipose tissue in men.
    Blouin K; Richard C; Brochu G; Hould FS; Lebel S; Marceau S; Biron S; Luu-The V; Tchernof A
    J Endocrinol; 2006 Dec; 191(3):637-49. PubMed ID: 17170221
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.