158 related articles for article (PubMed ID: 30227438)
1. MPT0B169 and MPT0B002, New Tubulin Inhibitors, Induce Growth Inhibition, G2/M Cell Cycle Arrest, and Apoptosis in Human Colorectal Cancer Cells.
Lee CH; Lin YF; Chen YC; Wong SM; Juan SH; Huang HM
Pharmacology; 2018; 102(5-6):262-271. PubMed ID: 30227438
[TBL] [Abstract][Full Text] [Related]
2. MPT0B169, a new tubulin inhibitor, inhibits cell growth and induces G2/M arrest in nonresistant and paclitaxel-resistant cancer cells.
Lee WH; Liu HE; Chang JY; Liou JP; Huang HM
Pharmacology; 2013; 92(1-2):90-8. PubMed ID: 23949011
[TBL] [Abstract][Full Text] [Related]
3. MPT0B169, a novel tubulin inhibitor, induces apoptosis in taxol-resistant acute myeloid leukemia cells through mitochondrial dysfunction and Mcl-1 downregulation.
Wang CC; Liu HE; Lee YL; Huang YW; Chen YJ; Liou JP; Huang HM
Tumour Biol; 2016 May; 37(5):6065-72. PubMed ID: 26608370
[TBL] [Abstract][Full Text] [Related]
4. MPT0B169, a New Antitubulin Agent, Inhibits Bcr-Abl Expression and Induces Mitochondrion-Mediated Apoptosis in Nonresistant and Imatinib-Resistant Chronic Myeloid Leukemia Cells.
Wong SM; Liu FH; Lee YL; Huang HM
PLoS One; 2016; 11(1):e0148093. PubMed ID: 26815740
[TBL] [Abstract][Full Text] [Related]
5. MPT0B002, a novel microtubule inhibitor, downregulates T315I mutant Bcr-Abl and induces apoptosis of imatinib-resistant chronic myeloid leukemia cells.
Yeh YY; Liou JP; Lee YL; Lin JY; Huang HM
Invest New Drugs; 2017 Aug; 35(4):427-435. PubMed ID: 28349229
[TBL] [Abstract][Full Text] [Related]
6. Methyl 5-[(1H-indol-3-yl)selanyl]-1H-benzoimidazol-2-ylcarbamate (M-24), a novel tubulin inhibitor, causes G2/M arrest and cell apoptosis by disrupting tubulin polymerization in human cervical and breast cancer cells.
Zuo D; Jiang X; Han M; Shen J; Lang B; Guan Q; Bai Z; Han C; Li Z; Zhang W; Wu Y
Toxicol In Vitro; 2017 Aug; 42():139-149. PubMed ID: 28412508
[TBL] [Abstract][Full Text] [Related]
7. MT-4 suppresses resistant ovarian cancer growth through targeting tubulin and HSP27.
Pai HC; Kumar S; Shen CC; Liou JP; Pan SL; Teng CM
PLoS One; 2015; 10(4):e0123819. PubMed ID: 25874627
[TBL] [Abstract][Full Text] [Related]
8. Synthesis of a terphenyl substituted 4-aza-2,3-didehydropodophyllotoxin analogues as inhibitors of tubulin polymerization and apoptosis inducers.
Kamal A; Tamboli JR; Nayak VL; Adil SF; Vishnuvardhan MV; Ramakrishna S
Bioorg Med Chem; 2014 May; 22(9):2714-23. PubMed ID: 24721832
[TBL] [Abstract][Full Text] [Related]
9. SKLB316, a novel small-molecule inhibitor of cell-cycle progression, induces G2/M phase arrest and apoptosis in vitro and inhibits tumor growth in vivo.
Xia Y; Lei Q; Zhu Y; Ye T; Wang N; Li G; Shi X; Liu Y; Shao B; Yin T; Zhao L; Wu W; Song X; Xiong Y; Wei Y; Yu L
Cancer Lett; 2014 Dec; 355(2):297-309. PubMed ID: 25301449
[TBL] [Abstract][Full Text] [Related]
10. 3-(3-Hydroxy-4-methoxyphenyl)-4-(3,4,5-trimethoxyphenyl)-1,2,5-selenadiazole (G-1103), a novel combretastatin A-4 analog, induces G2/M arrest and apoptosis by disrupting tubulin polymerization in human cervical HeLa cells and fibrosarcoma HT-1080 cells.
Zuo D; Guo D; Jiang X; Guan Q; Qi H; Xu J; Li Z; Yang F; Zhang W; Wu Y
Chem Biol Interact; 2015 Feb; 227():7-17. PubMed ID: 25529822
[TBL] [Abstract][Full Text] [Related]
11. A monomer purified from Paris polyphylla (PP-22) triggers S and G2/M phase arrest and apoptosis in human tongue squamous cell carcinoma SCC-15 by activating the p38/cdc25/cdc2 and caspase 8/caspase 3 pathways.
Ke JY; Zhang W; Gong RS; Cen WJ; Huang HQ; Li YR; Kong WD; Jiang JW
Tumour Biol; 2016 Nov; 37(11):14863-14872. PubMed ID: 27644244
[TBL] [Abstract][Full Text] [Related]
12. PP9, a steroidal saponin, induces G2/M arrest and apoptosis in human colorectal cancer cells by inhibiting the PI3K/Akt/GSK3β pathway.
Yao M; Li R; Yang Z; Ding Y; Zhang W; Li W; Liu M; Zhao C; Wang Y; Tang H; Wang J; Wen A
Chem Biol Interact; 2020 Nov; 331():109246. PubMed ID: 32877639
[TBL] [Abstract][Full Text] [Related]
13. 5-(3,4,5-trimethoxybenzoyl)-4-methyl-2-(p-tolyl) imidazol (BZML) targets tubulin and DNA to induce anticancer activity and overcome multidrug resistance in colorectal cancer cells.
Bai Z; Liu X; Guan Q; Ding N; Wei Q; Tong B; Zhao M; Zhang W; Ma L
Chem Biol Interact; 2020 Jan; 315():108886. PubMed ID: 31682804
[TBL] [Abstract][Full Text] [Related]
14. A Novel Resveratrol Based Tubulin Inhibitor Induces Mitotic Arrest and Activates Apoptosis in Cancer Cells.
Thomas E; Gopalakrishnan V; Hegde M; Kumar S; Karki SS; Raghavan SC; Choudhary B
Sci Rep; 2016 Oct; 6():34653. PubMed ID: 27748367
[TBL] [Abstract][Full Text] [Related]
15. Design and synthesis of imidazo[2,1-b]thiazole-chalcone conjugates: microtubule-destabilizing agents.
Kamal A; Balakrishna M; Nayak VL; Shaik TB; Faazil S; Nimbarte VD
ChemMedChem; 2014 Dec; 9(12):2766-80. PubMed ID: 25313981
[TBL] [Abstract][Full Text] [Related]
16. 5-(Furan-2-yl)-4-(3,4,5-trimethoxyphenyl)-3H-1,2-dithiol-3-one oxime (6f), a new synthetic compound, causes human fibrosarcoma HT-1080 cell apoptosis by disrupting tubulin polymerisation and inducing G2/M arrest.
Zuo D; Pang L; Shen J; Guan Q; Bai Z; Zhang H; Li Y; Lu G; Zhang W; Wu Y
Int J Oncol; 2017 Jun; 50(6):2069-2078. PubMed ID: 28440465
[TBL] [Abstract][Full Text] [Related]
17. MHY451 induces cell cycle arrest and apoptosis by ROS generation in HCT116 human colorectal cancer cells.
Hwang NL; Kang YJ; Sung B; Hwang SY; Jang JY; Oh HJ; Ahn YR; Kim DH; Kim SJ; Ullah S; Hossain MA; Moon HR; Chung HY; Kim ND
Oncol Rep; 2017 Sep; 38(3):1783-1789. PubMed ID: 28731136
[TBL] [Abstract][Full Text] [Related]
18. MC37, a new mono-carbonyl curcumin analog, induces G2/M cell cycle arrest and mitochondria-mediated apoptosis in human colorectal cancer cells.
Liang B; Liu Z; Cao Y; Zhu C; Zuo Y; Huang L; Wen G; Shang N; Chen Y; Yue X; Du J; Li B; Zhou B; Bu X
Eur J Pharmacol; 2017 Feb; 796():139-148. PubMed ID: 28024945
[TBL] [Abstract][Full Text] [Related]
19. A novel tubulin polymerization inhibitor, MPT0B206, downregulates Bcr-Abl expression and induces apoptosis in imatinib-sensitive and imatinib-resistant CML cells.
Chen CW; Lee YL; Liou JP; Liu YH; Liu CW; Chen TY; Huang HM
Apoptosis; 2016 Sep; 21(9):1008-18. PubMed ID: 27344662
[TBL] [Abstract][Full Text] [Related]
20. A molecular understanding of D-homoestrone-induced G2/M cell cycle arrest in HeLa human cervical carcinoma cells.
Minorics R; Bózsity N; Molnár J; Wölfling J; Mernyák E; Schneider G; Ocsovszki I; Zupkó I
J Cell Mol Med; 2015 Oct; 19(10):2365-74. PubMed ID: 26228523
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
