These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

167 related articles for article (PubMed ID: 30228186)

  • 1. K-Ras Lys-42 is crucial for its signaling, cell migration, and invasion.
    Choi BH; Philips MR; Chen Y; Lu L; Dai W
    J Biol Chem; 2018 Nov; 293(45):17574-17581. PubMed ID: 30228186
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Ras sumoylation in cell signaling and transformation.
    Dai W; Xie S; Chen C; Choi BH
    Semin Cancer Biol; 2021 Nov; 76():301-309. PubMed ID: 33812985
    [TBL] [Abstract][Full Text] [Related]  

  • 3. SUMOylation of Grb2 enhances the ERK activity by increasing its binding with Sos1.
    Qu Y; Chen Q; Lai X; Zhu C; Chen C; Zhao X; Deng R; Xu M; Yuan H; Wang Y; Yu J; Huang J
    Mol Cancer; 2014 Apr; 13():95. PubMed ID: 24775912
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Small G proteins Rac1 and Ras regulate serine/threonine protein phosphatase 5 (PP5)·extracellular signal-regulated kinase (ERK) complexes involved in the feedback regulation of Raf1.
    Mazalouskas MD; Godoy-Ruiz R; Weber DJ; Zimmer DB; Honkanen RE; Wadzinski BE
    J Biol Chem; 2014 Feb; 289(7):4219-32. PubMed ID: 24371145
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Rasfonin, a novel 2-pyrone derivative, induces ras-mutated Panc-1 pancreatic tumor cell death in nude mice.
    Xiao Z; Li L; Li Y; Zhou W; Cheng J; Liu F; Zheng P; Zhang Y; Che Y
    Cell Death Dis; 2014 May; 5(5):e1241. PubMed ID: 24853419
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Identification of Radil as a Ras binding partner and putative activator.
    Choi BH; Kou Z; Colon TM; Chen CH; Chen Y; Dai W
    J Biol Chem; 2021; 296():100314. PubMed ID: 33482197
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Induction of beta3-integrin gene expression by sustained activation of the Ras-regulated Raf-MEK-extracellular signal-regulated kinase signaling pathway.
    Woods D; Cherwinski H; Venetsanakos E; Bhat A; Gysin S; Humbert M; Bray PF; Saylor VL; McMahon M
    Mol Cell Biol; 2001 May; 21(9):3192-205. PubMed ID: 11287623
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Oncogenic Ras abrogates MEK SUMOylation that suppresses the ERK pathway and cell transformation.
    Kubota Y; O'Grady P; Saito H; Takekawa M
    Nat Cell Biol; 2011 Mar; 13(3):282-91. PubMed ID: 21336309
    [TBL] [Abstract][Full Text] [Related]  

  • 9. SUMOylation of the transcription factor ZFHX3 at Lys-2806 requires SAE1, UBC9, and PIAS2 and enhances its stability and function in cell proliferation.
    Wu R; Fang J; Liu M; A J; Liu J; Chen W; Li J; Ma G; Zhang Z; Zhang B; Fu L; Dong JT
    J Biol Chem; 2020 May; 295(19):6741-6753. PubMed ID: 32249212
    [TBL] [Abstract][Full Text] [Related]  

  • 10. K-ras mutation promotes ionizing radiation-induced invasion and migration of lung cancer in part via the Cathepsin L/CUX1 pathway.
    Wang L; Zhao Y; Xiong Y; Wang W; Fei Y; Tan C; Liang Z
    Exp Cell Res; 2018 Jan; 362(2):424-435. PubMed ID: 29246726
    [TBL] [Abstract][Full Text] [Related]  

  • 11. PIAS1-mediated sumoylation of focal adhesion kinase activates its autophosphorylation.
    Kadaré G; Toutant M; Formstecher E; Corvol JC; Carnaud M; Boutterin MC; Girault JA
    J Biol Chem; 2003 Nov; 278(48):47434-40. PubMed ID: 14500712
    [TBL] [Abstract][Full Text] [Related]  

  • 12. UBE2C, Directly Targeted by miR-548e-5p, Increases the Cellular Growth and Invasive Abilities of Cancer Cells Interacting with the EMT Marker Protein Zinc Finger E-box Binding Homeobox 1/2 in NSCLC.
    Jin D; Guo J; Wu Y; Du J; Wang X; An J; Hu B; Kong L; Di W; Wang W
    Theranostics; 2019; 9(7):2036-2055. PubMed ID: 31037155
    [No Abstract]   [Full Text] [Related]  

  • 13. Oncogenic K-Ras down-regulates Rac1 and RhoA activity and enhances migration and invasion of pancreatic carcinoma cells through activation of p38.
    Dreissigacker U; Mueller MS; Unger M; Siegert P; Genze F; Gierschik P; Giehl K
    Cell Signal; 2006 Aug; 18(8):1156-68. PubMed ID: 16257181
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Activation of focal adhesion kinase enhances the adhesion and invasion of pancreatic cancer cells via extracellular signal-regulated kinase-1/2 signaling pathway activation.
    Sawai H; Okada Y; Funahashi H; Matsuo Y; Takahashi H; Takeyama H; Manabe T
    Mol Cancer; 2005 Oct; 4():37. PubMed ID: 16209712
    [TBL] [Abstract][Full Text] [Related]  

  • 15. K-Ras promotes angiogenesis mediated by immortalized human pancreatic epithelial cells through mitogen-activated protein kinase signaling pathways.
    Matsuo Y; Campbell PM; Brekken RA; Sung B; Ouellette MM; Fleming JB; Aggarwal BB; Der CJ; Guha S
    Mol Cancer Res; 2009 Jun; 7(6):799-808. PubMed ID: 19509115
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Epidermal Growth Factor Receptor Signaling to the Mitogen Activated Protein Kinase Pathway Bypasses Ras in Pancreatic Cancer Cells.
    Lee S; Heinrich EL; Lu J; Lee W; Choi AH; Luu C; Chung V; Fakih M; Kim J
    Pancreas; 2016 Feb; 45(2):286-92. PubMed ID: 26262587
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The protein kinase MAP3K19 phosphorylates MAP2Ks and thereby activates ERK and JNK kinases and increases viability of KRAS-mutant lung cancer cells.
    Hoang VT; Nyswaner K; Torres-Ayuso P; Brognard J
    J Biol Chem; 2020 Jun; 295(25):8470-8479. PubMed ID: 32358059
    [TBL] [Abstract][Full Text] [Related]  

  • 18. ZEB1 suppression sensitizes KRAS mutant cancers to MEK inhibition by an IL17RD-dependent mechanism.
    Peng DH; Kundu ST; Fradette JJ; Diao L; Tong P; Byers LA; Wang J; Canales JR; Villalobos PA; Mino B; Yang Y; Minelli R; Peoples MD; Bristow CA; Heffernan TP; Carugo A; Wistuba II; Gibbons DL
    Sci Transl Med; 2019 Mar; 11(483):. PubMed ID: 30867319
    [TBL] [Abstract][Full Text] [Related]  

  • 19. RAS GTPases are modified by SUMOylation.
    Choi BH; Chen C; Philips M; Dai W
    Oncotarget; 2018 Jan; 9(4):4440-4450. PubMed ID: 29435114
    [TBL] [Abstract][Full Text] [Related]  

  • 20. H-Ras-specific activation of Rac-MKK3/6-p38 pathway: its critical role in invasion and migration of breast epithelial cells.
    Shin I; Kim S; Song H; Kim HR; Moon A
    J Biol Chem; 2005 Apr; 280(15):14675-83. PubMed ID: 15677464
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.