BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

155 related articles for article (PubMed ID: 30230312)

  • 1. A Robust Proton Flux (pHlux) Assay for Studying the Function and Inhibition of the Influenza A M2 Proton Channel.
    Santner P; Martins JMDS; Laursen JS; Behrendt L; Riber L; Olsen CA; Arkin IT; Winther JR; Willemoës M; Lindorff-Larsen K
    Biochemistry; 2018 Oct; 57(41):5949-5956. PubMed ID: 30230312
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Random Mutagenesis Analysis of the Influenza A M2 Proton Channel Reveals Novel Resistance Mutants.
    Santner P; Martins JMDS; Kampmeyer C; Hartmann-Petersen R; Laursen JS; Stein A; Olsen CA; Arkin IT; Winther JR; Willemoës M; Lindorff-Larsen K
    Biochemistry; 2018 Oct; 57(41):5957-5968. PubMed ID: 30230310
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Discovery of M2 channel blockers targeting the drug-resistant double mutants M2-S31N/L26I and M2-S31N/V27A from the influenza A viruses.
    Musharrafieh R; Ma C; Wang J
    Eur J Pharm Sci; 2020 Jan; 141():105124. PubMed ID: 31669761
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Designing inhibitors of M2 proton channel against H1N1 swine influenza virus.
    Du QS; Huang RB; Wang SQ; Chou KC
    PLoS One; 2010 Feb; 5(2):e9388. PubMed ID: 20186344
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Design and pharmacological characterization of inhibitors of amantadine-resistant mutants of the M2 ion channel of influenza A virus.
    Balannik V; Wang J; Ohigashi Y; Jing X; Magavern E; Lamb RA; Degrado WF; Pinto LH
    Biochemistry; 2009 Dec; 48(50):11872-82. PubMed ID: 19905033
    [TBL] [Abstract][Full Text] [Related]  

  • 6. 3-Azatetracyclo[5.2.1.1(5,8).0(1,5)]undecane derivatives: from wild-type inhibitors of the M2 ion channel of influenza A virus to derivatives with potent activity against the V27A mutant.
    Rey-Carrizo M; Torres E; Ma C; Barniol-Xicota M; Wang J; Wu Y; Naesens L; DeGrado WF; Lamb RA; Pinto LH; Vázquez S
    J Med Chem; 2013 Nov; 56(22):9265-74. PubMed ID: 24237039
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Viral M2 ion channel protein: a promising target for anti-influenza drug discovery.
    Moorthy NS; Poongavanam V; Pratheepa V
    Mini Rev Med Chem; 2014; 14(10):819-30. PubMed ID: 25342196
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Discovery of Potent Antivirals against Amantadine-Resistant Influenza A Viruses by Targeting the M2-S31N Proton Channel.
    Li F; Ma C; Hu Y; Wang Y; Wang J
    ACS Infect Dis; 2016 Oct; 2(10):726-733. PubMed ID: 27657178
    [TBL] [Abstract][Full Text] [Related]  

  • 9. An M2-V27A channel blocker demonstrates potent in vitro and in vivo antiviral activities against amantadine-sensitive and -resistant influenza A viruses.
    Hu Y; Musharrafieh R; Ma C; Zhang J; Smee DF; DeGrado WF; Wang J
    Antiviral Res; 2017 Apr; 140():45-54. PubMed ID: 28087313
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Recent advances in computational studies on influenza a virus M2 proton channel.
    Wang JF; Chou KC
    Mini Rev Med Chem; 2012 Sep; 12(10):971-8. PubMed ID: 22420575
    [TBL] [Abstract][Full Text] [Related]  

  • 11. New strategy for high throughput screening of anti-influenza virus M2 ion channel inhibitors.
    Li C; Long Y; Lin Z; Jie Y; Xiao Y; Yang L; Sun J; Ren Y; Chen L; Li Z
    Curr Pharm Des; 2013; 19(28):5146-55. PubMed ID: 23621591
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Novel spirothiazamenthane inhibitors of the influenza A M2 proton channel.
    Arns S; Balgi AD; Shimizu Y; Pfeifer TA; Kumar N; Shidmoossavee FS; Sun S; Tai SS; Agafitei O; Jaquith JB; Bourque E; Niikura M; Roberge M
    Eur J Med Chem; 2016 Sep; 120():64-73. PubMed ID: 27187859
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Inhibitors of the influenza A virus M2 proton channel discovered using a high-throughput yeast growth restoration assay.
    Balgi AD; Wang J; Cheng DY; Ma C; Pfeifer TA; Shimizu Y; Anderson HJ; Pinto LH; Lamb RA; DeGrado WF; Roberge M
    PLoS One; 2013; 8(2):e55271. PubMed ID: 23383318
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Drug-induced conformational and dynamical changes of the S31N mutant of the influenza M2 proton channel investigated by solid-state NMR.
    Williams JK; Tietze D; Wang J; Wu Y; DeGrado WF; Hong M
    J Am Chem Soc; 2013 Jul; 135(26):9885-97. PubMed ID: 23758317
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Structure and function of the influenza A M2 proton channel.
    Cady SD; Luo W; Hu F; Hong M
    Biochemistry; 2009 Aug; 48(31):7356-64. PubMed ID: 19601584
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Why bound amantadine fails to inhibit proton conductance according to simulations of the drug-resistant influenza A M2 (S31N).
    Gleed ML; Busath DD
    J Phys Chem B; 2015 Jan; 119(3):1225-31. PubMed ID: 25426702
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Drug inhibition and proton conduction mechanisms of the influenza a M2 proton channel.
    Gu R; Liu LA; Wei D
    Adv Exp Med Biol; 2015; 827():205-26. PubMed ID: 25387967
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Proton and cation transport activity of the M2 proton channel from influenza A virus.
    Leiding T; Wang J; Martinsson J; DeGrado WF; Arsköld SP
    Proc Natl Acad Sci U S A; 2010 Aug; 107(35):15409-14. PubMed ID: 20713739
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Structure and inhibition of the drug-resistant S31N mutant of the M2 ion channel of influenza A virus.
    Wang J; Wu Y; Ma C; Fiorin G; Wang J; Pinto LH; Lamb RA; Klein ML; Degrado WF
    Proc Natl Acad Sci U S A; 2013 Jan; 110(4):1315-20. PubMed ID: 23302696
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Functional studies and modeling of pore-lining residue mutants of the influenza a virus M2 ion channel.
    Balannik V; Carnevale V; Fiorin G; Levine BG; Lamb RA; Klein ML; Degrado WF; Pinto LH
    Biochemistry; 2010 Feb; 49(4):696-708. PubMed ID: 20028125
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.