BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

167 related articles for article (PubMed ID: 30237061)

  • 1. The roles of breast cancer resistance protein (BCRP/ABCG2) and multidrug resistance-associated proteins (MRPs/ABCCs) in the excretion of cycloicaritin-3-O-glucoronide in UGT1A1-overexpressing HeLa cells.
    Li S; Xu J; Yao Z; Hu L; Qin Z; Gao H; Krausz KW; Gonzalez FJ; Yao X
    Chem Biol Interact; 2018 Dec; 296():45-56. PubMed ID: 30237061
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Chemical inhibition and stable knock-down of efflux transporters leads to reduced glucuronidation of wushanicaritin in UGT1A1-overexpressing HeLa cells: the role of breast cancer resistance protein (BCRP) and multidrug resistance-associated proteins (MRPs) in the excretion of glucuronides.
    Qin Z; Li S; Yao Z; Hong X; Wu B; Krausz KW; Gonzalez FJ; Gao H; Yao X
    Food Funct; 2018 Mar; 9(3):1410-1423. PubMed ID: 29318243
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Efflux excretion of bisdemethoxycurcumin-O-glucuronide in UGT1A1-overexpressing HeLa cells: Identification of breast cancer resistance protein (BCRP) and multidrug resistance-associated proteins 1 (MRP1) as the glucuronide transporters.
    Yang J; Zhang B; Qin Z; Li S; Xu J; Yao Z; Zhang X; Gonzalez FJ; Yao X
    Biofactors; 2018 Nov; 44(6):558-569. PubMed ID: 30334318
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Characterization of chrysin glucuronidation in UGT1A1-overexpressing HeLa cells: elucidating the transporters responsible for efflux of glucuronide.
    Quan E; Wang H; Dong D; Zhang X; Wu B
    Drug Metab Dispos; 2015 Apr; 43(4):433-43. PubMed ID: 25595598
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mechanism of the efflux transport of demethoxycurcumin-O-glucuronides in HeLa cells stably transfected with UDP-glucuronosyltransferase 1A1.
    Zhang B; Yang J; Qin Z; Li S; Xu J; Yao Z; Zhang X; Gonzalez FJ; Yao X
    PLoS One; 2019; 14(5):e0217695. PubMed ID: 31150474
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Stable knock-down of efflux transporters leads to reduced glucuronidation in UGT1A1-overexpressing HeLa cells: the evidence for glucuronidation-transport interplay.
    Zhang X; Dong D; Wang H; Ma Z; Wang Y; Wu B
    Mol Pharm; 2015 Apr; 12(4):1268-78. PubMed ID: 25741749
    [TBL] [Abstract][Full Text] [Related]  

  • 7. UDP-glucuronosyltransferase (UGT) 1A9-overexpressing HeLa cells is an appropriate tool to delineate the kinetic interplay between breast cancer resistance protein (BRCP) and UGT and to rapidly identify the glucuronide substrates of BCRP.
    Jiang W; Xu B; Wu B; Yu R; Hu M
    Drug Metab Dispos; 2012 Feb; 40(2):336-45. PubMed ID: 22071170
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Efflux Transport Characterization of Resveratrol Glucuronides in UDP-Glucuronosyltransferase 1A1 Transfected HeLa Cells: Application of a Cellular Pharmacokinetic Model to Decipher the Contribution of Multidrug Resistance-Associated Protein 4.
    Wang S; Li F; Quan E; Dong D; Wu B
    Drug Metab Dispos; 2016 Apr; 44(4):485-8. PubMed ID: 26758854
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Identification of UGTs and BCRP as potential pharmacokinetic determinants of the natural flavonoid alpinetin.
    Qi C; Fu J; Zhao H; Xing H; Dong D; Wu B
    Xenobiotica; 2019 Mar; 49(3):276-283. PubMed ID: 29436891
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Efflux transport of estrogen glucuronides by human MRP2, MRP3, MRP4 and BCRP.
    Järvinen E; Deng F; Kidron H; Finel M
    J Steroid Biochem Mol Biol; 2018 Apr; 178():99-107. PubMed ID: 29175180
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Characterization of metabolic activity, isozyme contribution and species differences of bavachin, and identification of efflux transporters for bavachin-O-glucuronide in HeLa1A1 cells.
    Li Y; Xu C; Xu J; Qin Z; Li S; Hu L; Yao Z; Gonzalez FJ; Yao X
    J Pharm Pharmacol; 2020 Dec; 72(12):1771-1786. PubMed ID: 32648321
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Breast Cancer Resistance Protein and Multidrug Resistance Protein 2 Determine the Disposition of Esculetin-7-O-Glucuronide and 4-Methylesculetin-7-O-Glucuronide.
    Li Y; Song W; Ou X; Luo G; Xie Y; Sun R; Wang Y; Qi X; Hu M; Liu Z; Zhu L
    Drug Metab Dispos; 2019 Mar; 47(3):203-214. PubMed ID: 30602435
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Potential Determinants for Metabolic Fates and Inhibitory Effects of Isobavachalcone Involving in Human Cytochrome P450, UDP-Glucuronosyltransferase Enzymes, and Efflux Transporters.
    Qin Z; Wang P; Duan S; Wan X; Xing H; Yang J; Zhang X; Yao Z; Yao X
    J Pharm Sci; 2021 May; 110(5):2285-2294. PubMed ID: 33610566
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Sulfation disposition of liquiritigenin in SULT1A3 overexpressing HEK293 cells: The role of breast cancer resistance protein (BCRP) and multidrug resistance-associated protein 4 (MRP4) in sulfate efflux of liquiritigenin.
    Liu T; Zhang X; Zhang Y; Hou J; Fang D; Sun H; Li Q; Xie S
    Eur J Pharm Sci; 2018 Nov; 124():228-239. PubMed ID: 30176366
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The Efflux Mechanism of Fraxetin-
    Qin Z; Zhang B; Yang J; Li S; Xu J; Yao Z; Zhang X; Gonzalez FJ; Yao X
    Front Pharmacol; 2019; 10():496. PubMed ID: 31133859
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Selectivity in the Efflux of Glucuronides by Human Transporters: MRP4 Is Highly Active toward 4-Methylumbelliferone and 1-Naphthol Glucuronides, while MRP3 Exhibits Stereoselective Propranolol Glucuronide Transport.
    Järvinen E; Troberg J; Kidron H; Finel M
    Mol Pharm; 2017 Oct; 14(10):3299-3311. PubMed ID: 28850245
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Overexpression of MRP3 in HeLa-UGT1A9 Cells Enhances Glucuronidation Capability of the Cells.
    Zhou Q; Xia B; Yin T; He Y; Ye L; Hu M
    Curr Drug Metab; 2021; 22(10):772-783. PubMed ID: 34279197
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Disposition of Mianserin and Cyclizine in UGT2B10-Overexpressing Human Embryonic Kidney 293 Cells: Identification of UGT2B10 as a Novel N-Glucosidation Enzyme and Breast Cancer Resistance Protein as an N-Glucoside Transporter.
    Lu D; Dong D; Xie Q; Li Z; Wu B
    Drug Metab Dispos; 2018 Jul; 46(7):970-979. PubMed ID: 29691239
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Decreased Expression of Multidrug Resistance-Associated Protein 4 (MRP4/ABCC4) Leads to Reduced Glucuronidation of Flavonoids in UGT1A1-Overexpressing HeLa Cells: The Role of Futile Recycling.
    Sun H; Zhou X; Zhang X; Wu B
    J Agric Food Chem; 2015 Jul; 63(26):6001-8. PubMed ID: 26066637
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Efflux transport of nicotine, cotinine and trans-3'-hydroxycotinine glucuronides by human hepatic transporters.
    Järvinen E; Sjöstedt N; Koenderink JB; Kidron H; Finel M
    Basic Clin Pharmacol Toxicol; 2019 Dec; 125(6):490-498. PubMed ID: 31237077
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.