BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

429 related articles for article (PubMed ID: 30238389)

  • 21. Modeling Alzheimer's disease with iPSCs reveals stress phenotypes associated with intracellular Aβ and differential drug responsiveness.
    Kondo T; Asai M; Tsukita K; Kutoku Y; Ohsawa Y; Sunada Y; Imamura K; Egawa N; Yahata N; Okita K; Takahashi K; Asaka I; Aoi T; Watanabe A; Watanabe K; Kadoya C; Nakano R; Watanabe D; Maruyama K; Hori O; Hibino S; Choshi T; Nakahata T; Hioki H; Kaneko T; Naitoh M; Yoshikawa K; Yamawaki S; Suzuki S; Hata R; Ueno S; Seki T; Kobayashi K; Toda T; Murakami K; Irie K; Klein WL; Mori H; Asada T; Takahashi R; Iwata N; Yamanaka S; Inoue H
    Cell Stem Cell; 2013 Apr; 12(4):487-96. PubMed ID: 23434393
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Activation of glycogen synthase kinase-3 beta mediates β-amyloid induced neuritic damage in Alzheimer's disease.
    DaRocha-Souto B; Coma M; Pérez-Nievas BG; Scotton TC; Siao M; Sánchez-Ferrer P; Hashimoto T; Fan Z; Hudry E; Barroeta I; Serenó L; Rodríguez M; Sánchez MB; Hyman BT; Gómez-Isla T
    Neurobiol Dis; 2012 Jan; 45(1):425-37. PubMed ID: 21945540
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Modeling Late-Onset Sporadic Alzheimer's Disease through BMI1 Deficiency.
    Flamier A; El Hajjar J; Adjaye J; Fernandes KJ; Abdouh M; Bernier G
    Cell Rep; 2018 May; 23(9):2653-2666. PubMed ID: 29847796
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Targeting CCR3 to Reduce Amyloid-β Production, Tau Hyperphosphorylation, and Synaptic Loss in a Mouse Model of Alzheimer's Disease.
    Zhu C; Xu B; Sun X; Zhu Q; Sui Y
    Mol Neurobiol; 2017 Dec; 54(10):7964-7978. PubMed ID: 27878757
    [TBL] [Abstract][Full Text] [Related]  

  • 25. The exosome of adipose-derived stem cells reduces β-amyloid pathology and apoptosis of neuronal cells derived from the transgenic mouse model of Alzheimer's disease.
    Lee M; Ban JJ; Yang S; Im W; Kim M
    Brain Res; 2018 Jul; 1691():87-93. PubMed ID: 29625119
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Current advances on different kinases involved in tau phosphorylation, and implications in Alzheimer's disease and tauopathies.
    Ferrer I; Gomez-Isla T; Puig B; Freixes M; Ribé E; Dalfó E; Avila J
    Curr Alzheimer Res; 2005 Jan; 2(1):3-18. PubMed ID: 15977985
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Cholesterol Metabolism Is a Druggable Axis that Independently Regulates Tau and Amyloid-β in iPSC-Derived Alzheimer's Disease Neurons.
    van der Kant R; Langness VF; Herrera CM; Williams DA; Fong LK; Leestemaker Y; Steenvoorden E; Rynearson KD; Brouwers JF; Helms JB; Ovaa H; Giera M; Wagner SL; Bang AG; Goldstein LSB
    Cell Stem Cell; 2019 Mar; 24(3):363-375.e9. PubMed ID: 30686764
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Amyloid-β toxicity and tau hyperphosphorylation are linked via RCAN1 in Alzheimer's disease.
    Lloret A; Badia MC; Giraldo E; Ermak G; Alonso MD; Pallardó FV; Davies KJ; Viña J
    J Alzheimers Dis; 2011; 27(4):701-9. PubMed ID: 21876249
    [TBL] [Abstract][Full Text] [Related]  

  • 29. A three-dimensional human neural cell culture model of Alzheimer's disease.
    Choi SH; Kim YH; Hebisch M; Sliwinski C; Lee S; D'Avanzo C; Chen H; Hooli B; Asselin C; Muffat J; Klee JB; Zhang C; Wainger BJ; Peitz M; Kovacs DM; Woolf CJ; Wagner SL; Tanzi RE; Kim DY
    Nature; 2014 Nov; 515(7526):274-8. PubMed ID: 25307057
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Fuzhisan ameliorates Aβ production and tau phosphorylation in hippocampal of 11month old APP/PS1 transgenic mice: A Western blot study.
    Zhang ZX; Zhao RP; Wang DS; Wang AN
    Exp Gerontol; 2016 Nov; 84():88-95. PubMed ID: 27612601
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Neuropathogenic role of adenylate kinase-1 in Aβ-mediated tau phosphorylation via AMPK and GSK3β.
    Park H; Kam TI; Kim Y; Choi H; Gwon Y; Kim C; Koh JY; Jung YK
    Hum Mol Genet; 2012 Jun; 21(12):2725-37. PubMed ID: 22419736
    [TBL] [Abstract][Full Text] [Related]  

  • 32. The participation of insulin-like growth factor-binding protein 3 released by astrocytes in the pathology of Alzheimer's disease.
    Watanabe K; Uemura K; Asada M; Maesako M; Akiyama H; Shimohama S; Takahashi R; Kinoshita A
    Mol Brain; 2015 Dec; 8(1):82. PubMed ID: 26637371
    [TBL] [Abstract][Full Text] [Related]  

  • 33. A Large Panel of Isogenic APP and PSEN1 Mutant Human iPSC Neurons Reveals Shared Endosomal Abnormalities Mediated by APP β-CTFs, Not Aβ.
    Kwart D; Gregg A; Scheckel C; Murphy EA; Paquet D; Duffield M; Fak J; Olsen O; Darnell RB; Tessier-Lavigne M
    Neuron; 2019 Oct; 104(2):256-270.e5. PubMed ID: 31416668
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Stabilization of Microtubule-Unbound Tau via Tau Phosphorylation at Ser262/356 by Par-1/MARK Contributes to Augmentation of AD-Related Phosphorylation and Aβ42-Induced Tau Toxicity.
    Ando K; Maruko-Otake A; Ohtake Y; Hayashishita M; Sekiya M; Iijima KM
    PLoS Genet; 2016 Mar; 12(3):e1005917. PubMed ID: 27023670
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Potassium 2-(1-hydroxypentyl)-benzoate improves memory deficits and attenuates amyloid and τ pathologies in a mouse model of Alzheimer's disease.
    Peng Y; Hu Y; Xu S; Rong X; Li J; Li P; Wang L; Yang J; Wang X
    J Pharmacol Exp Ther; 2014 Aug; 350(2):361-74. PubMed ID: 24893984
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Increased susceptibility to Aβ toxicity in neuronal cultures derived from familial Alzheimer's disease (PSEN1-A246E) induced pluripotent stem cells.
    Armijo E; Gonzalez C; Shahnawaz M; Flores A; Davis B; Soto C
    Neurosci Lett; 2017 Feb; 639():74-81. PubMed ID: 28034781
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Probing the therapeutic potential of TRPC6 for Alzheimer's disease in live neurons from patient-specific iPSCs.
    Tao R; Lu R; Wang J; Zeng S; Zhang T; Guo W; Zhang X; Cheng Q; Yue C; Wang Y; Jing N
    J Mol Cell Biol; 2020 Oct; 12(10):807-816. PubMed ID: 32492143
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Alterations of ATG4A and LC3B in neurons derived from Alzheimer's disease patients.
    Shirotani K; Watanabe K; Hatta D; Kutoku Y; Ohsawa Y; Sunada Y; Kondo T; Inoue H; Iwata N
    Genes Cells; 2023 Apr; 28(4):319-325. PubMed ID: 36719634
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Inhibition of HDAC3 reverses Alzheimer's disease-related pathologies in vitro and in the 3xTg-AD mouse model.
    Janczura KJ; Volmar CH; Sartor GC; Rao SJ; Ricciardi NR; Lambert G; Brothers SP; Wahlestedt C
    Proc Natl Acad Sci U S A; 2018 Nov; 115(47):E11148-E11157. PubMed ID: 30397132
    [TBL] [Abstract][Full Text] [Related]  

  • 40. iPSCs-derived nerve-like cells from familial Alzheimer's disease PSEN 1 E280A reveal increased amyloid-beta levels and loss of the Y chromosome.
    Mendivil-Perez M; Velez-Pardo C; Kosik KS; Lopera F; Jimenez-Del-Rio M
    Neurosci Lett; 2019 Jun; 703():111-118. PubMed ID: 30904577
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 22.