536 related articles for article (PubMed ID: 30239641)
1. A feedback loop between dipeptide-repeat protein, TDP-43 and karyopherin-α mediates C9orf72-related neurodegeneration.
Solomon DA; Stepto A; Au WH; Adachi Y; Diaper DC; Hall R; Rekhi A; Boudi A; Tziortzouda P; Lee YB; Smith B; Bridi JC; Spinelli G; Dearlove J; Humphrey DM; Gallo JM; Troakes C; Fanto M; Soller M; Rogelj B; Parsons RB; Shaw CE; Hortobágyi T; Hirth F
Brain; 2018 Oct; 141(10):2908-2924. PubMed ID: 30239641
[TBL] [Abstract][Full Text] [Related]
2. Aberrant deposition of stress granule-resident proteins linked to C9orf72-associated TDP-43 proteinopathy.
Chew J; Cook C; Gendron TF; Jansen-West K; Del Rosso G; Daughrity LM; Castanedes-Casey M; Kurti A; Stankowski JN; Disney MD; Rothstein JD; Dickson DW; Fryer JD; Zhang YJ; Petrucelli L
Mol Neurodegener; 2019 Feb; 14(1):9. PubMed ID: 30767771
[TBL] [Abstract][Full Text] [Related]
3. Sense-encoded poly-GR dipeptide repeat proteins correlate to neurodegeneration and uniquely co-localize with TDP-43 in dendrites of repeat-expanded C9orf72 amyotrophic lateral sclerosis.
Saberi S; Stauffer JE; Jiang J; Garcia SD; Taylor AE; Schulte D; Ohkubo T; Schloffman CL; Maldonado M; Baughn M; Rodriguez MJ; Pizzo D; Cleveland D; Ravits J
Acta Neuropathol; 2018 Mar; 135(3):459-474. PubMed ID: 29196813
[TBL] [Abstract][Full Text] [Related]
4. C9orf72 poly GA RAN-translated protein plays a key role in amyotrophic lateral sclerosis via aggregation and toxicity.
Lee YB; Baskaran P; Gomez-Deza J; Chen HJ; Nishimura AL; Smith BN; Troakes C; Adachi Y; Stepto A; Petrucelli L; Gallo JM; Hirth F; Rogelj B; Guthrie S; Shaw CE
Hum Mol Genet; 2017 Dec; 26(24):4765-4777. PubMed ID: 28973350
[TBL] [Abstract][Full Text] [Related]
5. Transcription elongation factor AFF2/FMR2 regulates expression of expanded GGGGCC repeat-containing C9ORF72 allele in ALS/FTD.
Yuva-Aydemir Y; Almeida S; Krishnan G; Gendron TF; Gao FB
Nat Commun; 2019 Nov; 10(1):5466. PubMed ID: 31784536
[TBL] [Abstract][Full Text] [Related]
6. C9ORF72 dipeptide repeat poly-GA inclusions promote intracellular aggregation of phosphorylated TDP-43.
Nonaka T; Masuda-Suzukake M; Hosokawa M; Shimozawa A; Hirai S; Okado H; Hasegawa M
Hum Mol Genet; 2018 Aug; 27(15):2658-2670. PubMed ID: 29750243
[TBL] [Abstract][Full Text] [Related]
7.
Cook CN; Wu Y; Odeh HM; Gendron TF; Jansen-West K; Del Rosso G; Yue M; Jiang P; Gomes E; Tong J; Daughrity LM; Avendano NM; Castanedes-Casey M; Shao W; Oskarsson B; Tomassy GS; McCampbell A; Rigo F; Dickson DW; Shorter J; Zhang YJ; Petrucelli L
Sci Transl Med; 2020 Sep; 12(559):. PubMed ID: 32878979
[TBL] [Abstract][Full Text] [Related]
8. C9orf72 ALS-FTD: recent evidence for dysregulation of the autophagy-lysosome pathway at multiple levels.
Beckers J; Tharkeshwar AK; Van Damme P
Autophagy; 2021 Nov; 17(11):3306-3322. PubMed ID: 33632058
[TBL] [Abstract][Full Text] [Related]
9. UBQLN2-HSP70 axis reduces poly-Gly-Ala aggregates and alleviates behavioral defects in the C9ORF72 animal model.
Zhang K; Wang A; Zhong K; Qi S; Wei C; Shu X; Tu WY; Xu W; Xia C; Xiao Y; Chen A; Bai L; Zhang J; Luo B; Wang W; Shen C
Neuron; 2021 Jun; 109(12):1949-1962.e6. PubMed ID: 33991504
[TBL] [Abstract][Full Text] [Related]
10. Dipeptide repeat protein inclusions are rare in the spinal cord and almost absent from motor neurons in C9ORF72 mutant amyotrophic lateral sclerosis and are unlikely to cause their degeneration.
Gomez-Deza J; Lee YB; Troakes C; Nolan M; Al-Sarraj S; Gallo JM; Shaw CE
Acta Neuropathol Commun; 2015 Jun; 3():38. PubMed ID: 26108573
[TBL] [Abstract][Full Text] [Related]
11. Open Access: A Role for p53 in c9ALS/FTD?
Fare CM; Shorter J
Trends Genet; 2021 May; 37(5):404-406. PubMed ID: 33551183
[TBL] [Abstract][Full Text] [Related]
12. Circadian sleep/wake-associated cells show dipeptide repeat protein aggregates in C9orf72-related ALS and FTLD cases.
Dedeene L; Van Schoor E; Vandenberghe R; Van Damme P; Poesen K; Thal DR
Acta Neuropathol Commun; 2019 Dec; 7(1):189. PubMed ID: 31791419
[TBL] [Abstract][Full Text] [Related]
13. The mTORC2/AKT/VCP axis is associated with quality control of the stalled translation of poly(GR) dipeptide repeats in C9-ALS/FTD.
Li Y; Geng J; Rimal S; Wang H; Liu X; Lu B; Li S
J Biol Chem; 2023 Mar; 299(3):102995. PubMed ID: 36764521
[TBL] [Abstract][Full Text] [Related]
14. Cell-to-cell transmission of C9orf72 poly-(Gly-Ala) triggers key features of ALS/FTD.
Khosravi B; LaClair KD; Riemenschneider H; Zhou Q; Frottin F; Mareljic N; Czuppa M; Farny D; Hartmann H; Michaelsen M; Arzberger T; Hartl FU; Hipp MS; Edbauer D
EMBO J; 2020 Apr; 39(8):e102811. PubMed ID: 32175624
[TBL] [Abstract][Full Text] [Related]
15. Cytoplasmic poly-GA aggregates impair nuclear import of TDP-43 in C9orf72 ALS/FTLD.
Khosravi B; Hartmann H; May S; Möhl C; Ederle H; Michaelsen M; Schludi MH; Dormann D; Edbauer D
Hum Mol Genet; 2017 Feb; 26(4):790-800. PubMed ID: 28040728
[TBL] [Abstract][Full Text] [Related]
16. Prevalence of brain and spinal cord inclusions, including dipeptide repeat proteins, in patients with the C9ORF72 hexanucleotide repeat expansion: a systematic neuropathological review.
Schipper LJ; Raaphorst J; Aronica E; Baas F; de Haan R; de Visser M; Troost D
Neuropathol Appl Neurobiol; 2016 Oct; 42(6):547-60. PubMed ID: 26373655
[TBL] [Abstract][Full Text] [Related]
17. Drosha inclusions are new components of dipeptide-repeat protein aggregates in FTLD-TDP and ALS C9orf72 expansion cases.
Porta S; Kwong LK; Trojanowski JQ; Lee VM
J Neuropathol Exp Neurol; 2015 Apr; 74(4):380-7. PubMed ID: 25756586
[TBL] [Abstract][Full Text] [Related]
18. The Hairpin Form of r(G
Wang ZF; Ursu A; Childs-Disney JL; Guertler R; Yang WY; Bernat V; Rzuczek SG; Fuerst R; Zhang YJ; Gendron TF; Yildirim I; Dwyer BG; Rice JE; Petrucelli L; Disney MD
Cell Chem Biol; 2019 Feb; 26(2):179-190.e12. PubMed ID: 30503283
[TBL] [Abstract][Full Text] [Related]
19. Insights into C9ORF72-Related ALS/FTD from Drosophila and iPSC Models.
Yuva-Aydemir Y; Almeida S; Gao FB
Trends Neurosci; 2018 Jul; 41(7):457-469. PubMed ID: 29729808
[TBL] [Abstract][Full Text] [Related]
20. Quantitative analysis and clinico-pathological correlations of different dipeptide repeat protein pathologies in C9ORF72 mutation carriers.
Mackenzie IR; Frick P; Grässer FA; Gendron TF; Petrucelli L; Cashman NR; Edbauer D; Kremmer E; Prudlo J; Troost D; Neumann M
Acta Neuropathol; 2015 Dec; 130(6):845-61. PubMed ID: 26374446
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
