262 related articles for article (PubMed ID: 30239932)
1. I260Q DNA polymerase β highlights precatalytic conformational rearrangements critical for fidelity.
Liptak C; Mahmoud MM; Eckenroth BE; Moreno MV; East K; Alnajjar KS; Huang J; Towle-Weicksel JB; Doublié S; Loria JP; Sweasy JB
Nucleic Acids Res; 2018 Nov; 46(20):10740-10756. PubMed ID: 30239932
[TBL] [Abstract][Full Text] [Related]
2. The nature of the DNA substrate influences pre-catalytic conformational changes of DNA polymerase β.
Huang J; Alnajjar KS; Mahmoud MM; Eckenroth B; Doublié S; Sweasy JB
J Biol Chem; 2018 Sep; 293(39):15084-15094. PubMed ID: 30068550
[TBL] [Abstract][Full Text] [Related]
3. Using single-molecule FRET to probe the nucleotide-dependent conformational landscape of polymerase β-DNA complexes.
Fijen C; Mahmoud MM; Kronenberg M; Kaup R; Fontana M; Towle-Weicksel JB; Sweasy JB; Hohlbein J
J Biol Chem; 2020 Jul; 295(27):9012-9020. PubMed ID: 32385112
[TBL] [Abstract][Full Text] [Related]
4. Regulation of DNA repair fidelity by molecular checkpoints: "gates" in DNA polymerase beta's substrate selection.
Radhakrishnan R; Arora K; Wang Y; Beard WA; Wilson SH; Schlick T
Biochemistry; 2006 Dec; 45(51):15142-56. PubMed ID: 17176036
[TBL] [Abstract][Full Text] [Related]
5. Defective Nucleotide Release by DNA Polymerase β Mutator Variant E288K Is the Basis of Its Low Fidelity.
Mahmoud MM; Schechter A; Alnajjar KS; Huang J; Towle-Weicksel J; Eckenroth BE; Doublié S; Sweasy JB
Biochemistry; 2017 Oct; 56(41):5550-5559. PubMed ID: 28945359
[TBL] [Abstract][Full Text] [Related]
6. Mismatch-induced conformational distortions in polymerase beta support an induced-fit mechanism for fidelity.
Arora K; Beard WA; Wilson SH; Schlick T
Biochemistry; 2005 Oct; 44(40):13328-41. PubMed ID: 16201758
[TBL] [Abstract][Full Text] [Related]
7. DNA Polymerase β in the Context of Cancer.
Sawyer DL; Sweasy JB
Crit Rev Oncog; 2022; 27(2):17-33. PubMed ID: 36734870
[TBL] [Abstract][Full Text] [Related]
8. Modifying the Basicity of the dNTP Leaving Group Modulates Precatalytic Conformational Changes of DNA Polymerase β.
Alnajjar KS; Wang K; Alvarado-Cruz I; Chavira C; Negahbani A; Nakhjiri M; Minard C; Garcia-Barboza B; Kashemirov BA; McKenna CE; Goodman MF; Sweasy JB
Biochemistry; 2024 Jun; 63(11):1412-1422. PubMed ID: 38780930
[TBL] [Abstract][Full Text] [Related]
9. Structural changes in the hydrophobic hinge region adversely affect the activity and fidelity of the I260Q mutator DNA polymerase β.
Gridley CL; Rangarajan S; Firbank S; Dalal S; Sweasy JB; Jaeger J
Biochemistry; 2013 Jun; 52(25):4422-32. PubMed ID: 23651085
[TBL] [Abstract][Full Text] [Related]
10. Effect of DNA polymerase beta loop variants on discrimination of O6-methyldeoxyguanosine modification present in the nucleotide versus template substrate.
Hamid S; Eckert KA
Biochemistry; 2005 Aug; 44(30):10378-87. PubMed ID: 16042415
[TBL] [Abstract][Full Text] [Related]
11. DNA polymerase beta: contributions of template-positioning and dNTP triphosphate-binding residues to catalysis and fidelity.
Kraynov VS; Showalter AK; Liu J; Zhong X; Tsai MD
Biochemistry; 2000 Dec; 39(51):16008-15. PubMed ID: 11123928
[TBL] [Abstract][Full Text] [Related]
12. Modifying the beta,gamma leaving-group bridging oxygen alters nucleotide incorporation efficiency, fidelity, and the catalytic mechanism of DNA polymerase beta.
Sucato CA; Upton TG; Kashemirov BA; Batra VK; Martínek V; Xiang Y; Beard WA; Pedersen LC; Wilson SH; McKenna CE; Florián J; Warshel A; Goodman MF
Biochemistry; 2007 Jan; 46(2):461-71. PubMed ID: 17209556
[TBL] [Abstract][Full Text] [Related]
13. In silico evidence for DNA polymerase-beta's substrate-induced conformational change.
Arora K; Schlick T
Biophys J; 2004 Nov; 87(5):3088-99. PubMed ID: 15507687
[TBL] [Abstract][Full Text] [Related]
14. A DNA polymerase beta mutator mutant with reduced nucleotide discrimination and increased protein stability.
Shah AM; Conn DA; Li SX; Capaldi A; Jäger J; Sweasy JB
Biochemistry; 2001 Sep; 40(38):11372-81. PubMed ID: 11560485
[TBL] [Abstract][Full Text] [Related]
15. Efficiency and fidelity of human DNA polymerases λ and β during gap-filling DNA synthesis.
Brown JA; Pack LR; Sanman LE; Suo Z
DNA Repair (Amst); 2011 Jan; 10(1):24-33. PubMed ID: 20961817
[TBL] [Abstract][Full Text] [Related]
16. Hinge residue I174 is critical for proper dNTP selection by DNA polymerase beta.
Yamtich J; Starcevic D; Lauper J; Smith E; Shi I; Rangarajan S; Jaeger J; Sweasy JB
Biochemistry; 2010 Mar; 49(11):2326-34. PubMed ID: 20108981
[TBL] [Abstract][Full Text] [Related]
17. Fluorescence resonance energy transfer studies of DNA polymerase β: the critical role of fingers domain movements and a novel non-covalent step during nucleotide selection.
Towle-Weicksel JB; Dalal S; Sohl CD; Doublié S; Anderson KS; Sweasy JB
J Biol Chem; 2014 Jun; 289(23):16541-50. PubMed ID: 24764311
[TBL] [Abstract][Full Text] [Related]
18. A pre-catalytic non-covalent step governs DNA polymerase β fidelity.
Alnajjar KS; Krylov IS; Negahbani A; Haratipour P; Kashemirov BA; Huang J; Mahmoud M; McKenna CE; Goodman MF; Sweasy JB
Nucleic Acids Res; 2019 Dec; 47(22):11839-11849. PubMed ID: 31732732
[TBL] [Abstract][Full Text] [Related]
19. Substrate-dependent millisecond domain motions in DNA polymerase β.
Berlow RB; Swain M; Dalal S; Sweasy JB; Loria JP
J Mol Biol; 2012 Jun; 419(3-4):171-82. PubMed ID: 22446382
[TBL] [Abstract][Full Text] [Related]
20. Transitions in DNA polymerase β μs-ms dynamics related to substrate binding and catalysis.
DeRose EF; Kirby TW; Mueller GA; Beard WA; Wilson SH; London RE
Nucleic Acids Res; 2018 Aug; 46(14):7309-7322. PubMed ID: 29917149
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
