These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

133 related articles for article (PubMed ID: 30247889)

  • 1. Structural Insight into Enantioselective Inversion of an Alcohol Dehydrogenase Reveals a "Polar Gate" in Stereorecognition of Diaryl Ketones.
    Zhou J; Wang Y; Xu G; Wu L; Han R; Schwaneberg U; Rao Y; Zhao YL; Zhou J; Ni Y
    J Am Chem Soc; 2018 Oct; 140(39):12645-12654. PubMed ID: 30247889
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Structural basis for a highly (S)-enantioselective reductase towards aliphatic ketones with only one carbon difference between side chain.
    Koesoema AA; Sugiyama Y; Xu Z; Standley DM; Senda M; Senda T; Matsuda T
    Appl Microbiol Biotechnol; 2019 Dec; 103(23-24):9543-9553. PubMed ID: 31482280
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Reversible control of enantioselectivity by the length of ketone substituent in biocatalytic reduction.
    Koesoema AA; Sugiyama Y; Sriwong KT; Xu Z; Verina S; Standley DM; Senda M; Senda T; Matsuda T
    Appl Microbiol Biotechnol; 2019 Dec; 103(23-24):9529-9541. PubMed ID: 31720775
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Relaxation of nonproductive binding and increased rate of coenzyme release in an alcohol dehydrogenase increases turnover with a nonpreferred alcohol enantiomer.
    Hamnevik E; Enugala TR; Maurer D; Ntuku S; Oliveira A; Dobritzsch D; Widersten M
    FEBS J; 2017 Nov; 284(22):3895-3914. PubMed ID: 28963762
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Inversion of substrate stereoselectivity of horse liver alcohol dehydrogenase by substitutions of Ser-48 and Phe-93.
    Kim K; Plapp BV
    Chem Biol Interact; 2017 Oct; 276():77-87. PubMed ID: 28025168
    [TBL] [Abstract][Full Text] [Related]  

  • 6. I86A/C295A mutant secondary alcohol dehydrogenase from Thermoanaerobacter ethanolicus has broadened substrate specificity for aryl ketones.
    Nealon CM; Welsh TP; Kim CS; Phillips RS
    Arch Biochem Biophys; 2016 Sep; 606():151-6. PubMed ID: 27495738
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Induced axial chirality in biocatalytic asymmetric ketone reduction.
    Agudo R; Roiban GD; Reetz MT
    J Am Chem Soc; 2013 Feb; 135(5):1665-8. PubMed ID: 23075382
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Facile Stereoselective Reduction of Prochiral Ketones by using an F
    Martin C; Tjallinks G; Trajkovic M; Fraaije MW
    Chembiochem; 2021 Jan; 22(1):156-159. PubMed ID: 32935896
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Impact and relevance of alcohol dehydrogenase enantioselectivities on biotechnological applications.
    Koesoema AA; Standley DM; Senda T; Matsuda T
    Appl Microbiol Biotechnol; 2020 Apr; 104(7):2897-2909. PubMed ID: 32060695
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Structural basis for substrate specificity differences of horse liver alcohol dehydrogenase isozymes.
    Adolph HW; Zwart P; Meijers R; Hubatsch I; Kiefer M; Lamzin V; Cedergren-Zeppezauer E
    Biochemistry; 2000 Oct; 39(42):12885-97. PubMed ID: 11041853
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Atomic resolution structures of R-specific alcohol dehydrogenase from Lactobacillus brevis provide the structural bases of its substrate and cosubstrate specificity.
    Schlieben NH; Niefind K; Müller J; Riebel B; Hummel W; Schomburg D
    J Mol Biol; 2005 Jun; 349(4):801-13. PubMed ID: 15896805
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Purification and characterization of an anti-Prelog alcohol dehydrogenase from Oenococcus oeni that reduces 2-octanone to (R)-2-octanol.
    Meng F; Xu Y
    Biotechnol Lett; 2010 Apr; 32(4):533-7. PubMed ID: 20035369
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Insights into the general and efficient cross McMurry reactions between ketones.
    Duan XF; Zeng J; Lü JW; Zhang ZB
    J Org Chem; 2006 Dec; 71(26):9873-6. PubMed ID: 17168612
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Manipulating the stereoselectivity of a thermostable alcohol dehydrogenase by directed evolution for efficient asymmetric synthesis of arylpropanols.
    Dong Y; Yao P; Cui Y; Wu Q; Zhu D; Li G; Reetz MT
    Biol Chem; 2019 Feb; 400(3):313-321. PubMed ID: 30269104
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Screening, Molecular Cloning, and Biochemical Characterization of an Alcohol Dehydrogenase from Pichia pastoris Useful for the Kinetic Resolution of a Racemic β-Hydroxy-β-trifluoromethyl Ketone.
    Bulut D; Duangdee N; Gröger H; Berkessel A; Hummel W
    Chembiochem; 2016 Jul; 17(14):1349-58. PubMed ID: 27123855
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Mutation of cysteine-295 to alanine in secondary alcohol dehydrogenase from Thermoanaerobacter ethanolicus affects the enantioselectivity and substrate specificity of ketone reductions.
    Heiss C; Laivenieks M; Zeikus JG; Phillips RS
    Bioorg Med Chem; 2001 Jul; 9(7):1659-66. PubMed ID: 11425565
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Methodology Development in Directed Evolution: Exploring Options when Applying Triple-Code Saturation Mutagenesis.
    Qu G; Lonsdale R; Yao P; Li G; Liu B; Reetz MT; Sun Z
    Chembiochem; 2018 Feb; 19(3):239-246. PubMed ID: 29314451
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Crystal structures of mouse class II alcohol dehydrogenase reveal determinants of substrate specificity and catalytic efficiency.
    Svensson S; Höög JO; Schneider G; Sandalova T
    J Mol Biol; 2000 Sep; 302(2):441-53. PubMed ID: 10970744
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Substrate specificity and stereoselectivity of horse liver alcohol dehydrogenase. Kinetic evaluation of binding and activation parameters controlling the catalytic cycles of unbranched, acyclic secondary alcohols and ketones as substrates of the native and active-site-specific Co(II)-substituted enzyme.
    Adolph HW; Maurer P; Schneider-Bernlöhr H; Sartorius C; Zeppezauer M
    Eur J Biochem; 1991 Nov; 201(3):615-25. PubMed ID: 1935957
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Structural insights into substrate specificity and solvent tolerance in alcohol dehydrogenase ADH-'A' from Rhodococcus ruber DSM 44541.
    Karabec M; Łyskowski A; Tauber KC; Steinkellner G; Kroutil W; Grogan G; Gruber K
    Chem Commun (Camb); 2010 Sep; 46(34):6314-6. PubMed ID: 20676439
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.