BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

306 related articles for article (PubMed ID: 30248511)

  • 1. Synthesis, antimicrobial activity and molecular modeling study of 3-(5-amino-(2H)-1,2,4-triazol-3-yl]-naphthyridinones as potential DNA-gyrase inhibitors.
    Mohamed NG; Sheha MM; Hassan HY; Abdel-Hafez LJM; Omar FA
    Bioorg Chem; 2018 Dec; 81():599-611. PubMed ID: 30248511
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Novel 1,2,4-oxadiazole-chalcone/oxime hybrids as potential antibacterial DNA gyrase inhibitors: Design, synthesis, ADMET prediction and molecular docking study.
    Ibrahim TS; Almalki AJ; Moustafa AH; Allam RM; Abuo-Rahma GEA; El Subbagh HI; Mohamed MFA
    Bioorg Chem; 2021 Jun; 111():104885. PubMed ID: 33838559
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Molecular docking, discovery, synthesis, and pharmacological properties of new 6-substituted-2-(3-phenoxyphenyl)-4-phenyl quinoline derivatives; an approach to developing potent DNA gyrase inhibitors/antibacterial agents.
    Alagumuthu M; Arumugam S
    Bioorg Med Chem; 2017 Feb; 25(4):1448-1455. PubMed ID: 28094220
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Design, green one-pot synthesis and molecular docking study of novel N,N-bis(cyanoacetyl)hydrazines and bis-coumarins as effective inhibitors of DNA gyrase and topoisomerase IV.
    Metwally NH; Abdallah SO; Mohsen MMA
    Bioorg Chem; 2020 Apr; 97():103672. PubMed ID: 32145481
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Novel coumarin-thiazolyl ester derivatives as potential DNA gyrase Inhibitors: Design, synthesis, and antibacterial activity.
    Liu H; Xia DG; Chu ZW; Hu R; Cheng X; Lv XH
    Bioorg Chem; 2020 Jul; 100():103907. PubMed ID: 32413631
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthesis, antimicrobial, cytotoxic and E. coli DNA gyrase inhibitory activities of coumarinyl amino alcohols.
    Priyanka ; Singh V; Ekta ; Katiyar D
    Bioorg Chem; 2017 Apr; 71():120-127. PubMed ID: 28196603
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Design and synthesis of novel 1H-tetrazol-5-amine based potent antimicrobial agents: DNA topoisomerase IV and gyrase affinity evaluation supported by molecular docking studies.
    Szulczyk D; Dobrowolski MA; Roszkowski P; Bielenica A; Stefańska J; Koliński M; Kmiecik S; Jóźwiak M; Wrzosek M; Olejarz W; Struga M
    Eur J Med Chem; 2018 Aug; 156():631-640. PubMed ID: 30031974
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Novel anti-tubercular and antibacterial based benzosuberone-thiazole moieties: Synthesis, molecular docking analysis, DNA gyrase supercoiling and ATPase activity.
    Omar MA; Masaret GS; Abbas EMH; Abdel-Aziz MM; Harras MF; Farghaly TA
    Bioorg Chem; 2020 Nov; 104():104316. PubMed ID: 33022549
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthesis, antimicrobial evaluation, DNA gyrase inhibition, and in silico pharmacokinetic studies of novel quinoline derivatives.
    El-Shershaby MH; El-Gamal KM; Bayoumi AH; El-Adl K; Ahmed HEA; Abulkhair HS
    Arch Pharm (Weinheim); 2021 Feb; 354(2):e2000277. PubMed ID: 33078877
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Computational Approaches to Develop Isoquinoline Based Antibiotics through DNA Gyrase Inhibition Mechanisms Unveiled through Antibacterial Evaluation and Molecular Docking.
    Alagumuthu M; Muralidharan VP; Andrew M; Ahmed MH; Iyer SK; Arumugam S
    Mol Inform; 2018 Dec; 37(12):e1800048. PubMed ID: 30051592
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Design, synthesis, and antibacterial evaluation of new quinoline-1,3,4-oxadiazole and quinoline-1,2,4-triazole hybrids as potential inhibitors of DNA gyrase and topoisomerase IV.
    Hofny HA; Mohamed MFA; Gomaa HAM; Abdel-Aziz SA; Youssif BGM; El-Koussi NA; Aboraia AS
    Bioorg Chem; 2021 Jul; 112():104920. PubMed ID: 33910078
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthesis, and antibacterial activity of novel 4,5-dihydro-1H-pyrazole derivatives as DNA gyrase inhibitors.
    Liu JJ; Sun J; Fang YB; Yang YA; Jiao RH; Zhu HL
    Org Biomol Chem; 2014 Feb; 12(6):998-1008. PubMed ID: 24382549
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Discovery of novel multi-substituted benzo-indole pyrazole schiff base derivatives with antibacterial activity targeting DNA gyrase.
    Liu H; Chu ZW; Xia DG; Cao HQ; Lv XH
    Bioorg Chem; 2020 Jun; 99():103807. PubMed ID: 32272364
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Design, synthesis, in vitro antimicrobial evaluation and molecular docking studies of indol-2-one tagged with morpholinosulfonyl moiety as DNA gyrase inhibitors.
    Salem MA; Ragab A; El-Khalafawy A; Makhlouf AH; Askar AA; Ammar YA
    Bioorg Chem; 2020 Mar; 96():103619. PubMed ID: 32036161
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Discovery of New Schiff Bases Tethered Pyrazole Moiety: Design, Synthesis, Biological Evaluation, and Molecular Docking Study as Dual Targeting DHFR/DNA Gyrase Inhibitors with Immunomodulatory Activity.
    Hassan AS; Askar AA; Naglah AM; Almehizia AA; Ragab A
    Molecules; 2020 Jun; 25(11):. PubMed ID: 32498469
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis and In Silico Molecular Docking Studies on Substituted Piperic Acid Derivatives as Inhibitors of Bacterial DNA Gyrase.
    Chopra B; Dhingra AK; Prasad DN; Bhardwaj S; Dubey S
    Curr Comput Aided Drug Des; 2020; 16(3):281-294. PubMed ID: 31288729
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Drug efficacy of novel 3-O-methoxy-4-halo disubstituted 5,7-dimethoxy chromans; evaluated via DNA gyrase inhibition, bacterial cell wall lesion and antibacterial prospective.
    Ponnusamy T; Alagumuthu M; Thamaraiselvi S
    Bioorg Med Chem; 2018 Jul; 26(12):3438-3452. PubMed ID: 29803359
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Design, synthesis, antibacterial evaluation, and computational studies of hybrid oxothiazolidin-1,2,4-triazole scaffolds.
    Pathak P; Novak J; Shukla PK; Grishina M; Potemkin V; Verma A
    Arch Pharm (Weinheim); 2021 Jun; 354(6):e2000473. PubMed ID: 33656194
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Extending the N-linked aminopiperidine class to the mycobacterial gyrase domain: pharmacophore mapping from known antibacterial leads.
    Bobesh KA; Renuka J; Jeankumar VU; Shruti SK; Sridevi JP; Yogeeswari P; Sriram D
    Eur J Med Chem; 2014 Oct; 85():593-604. PubMed ID: 25127151
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Pyridine-3-carboxamide-6-yl-ureas as novel inhibitors of bacterial DNA gyrase: structure based design, synthesis, SAR and antimicrobial activity.
    Yule IA; Czaplewski LG; Pommier S; Davies DT; Narramore SK; Fishwick CW
    Eur J Med Chem; 2014 Oct; 86():31-8. PubMed ID: 25137573
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.