209 related articles for article (PubMed ID: 30249303)
1. Neurodegeneration in SCA14 is associated with increased PKCγ kinase activity, mislocalization and aggregation.
Wong MMK; Hoekstra SD; Vowles J; Watson LM; Fuller G; Németh AH; Cowley SA; Ansorge O; Talbot K; Becker EBE
Acta Neuropathol Commun; 2018 Sep; 6(1):99. PubMed ID: 30249303
[TBL] [Abstract][Full Text] [Related]
2. Increased biological activity of protein Kinase C gamma is not required in Spinocerebellar ataxia 14.
Shimobayashi E; Kapfhammer JP
Mol Brain; 2017 Jul; 10(1):34. PubMed ID: 28738819
[TBL] [Abstract][Full Text] [Related]
3. A New Mouse Model Related to SCA14 Carrying a Pseudosubstrate Domain Mutation in PKCγ Shows Perturbed Purkinje Cell Maturation and Ataxic Motor Behavior.
Shimobayashi E; Kapfhammer JP
J Neurosci; 2021 Mar; 41(9):2053-2068. PubMed ID: 33478986
[TBL] [Abstract][Full Text] [Related]
4. Spinocerebellar ataxia type 14 caused by a nonsense mutation in the PRKCG gene.
Shirafuji T; Shimazaki H; Miyagi T; Ueyama T; Adachi N; Tanaka S; Hide I; Saito N; Sakai N
Mol Cell Neurosci; 2019 Jul; 98():46-53. PubMed ID: 31158466
[TBL] [Abstract][Full Text] [Related]
5. Transcriptome Profile of a New Mouse Model of Spinocerebellar Ataxia Type 14 Implies Changes in Cerebellar Development.
Mezey SE; Kapfhammer JP; Shimobayashi E
Genes (Basel); 2022 Aug; 13(8):. PubMed ID: 36011327
[TBL] [Abstract][Full Text] [Related]
6. SCA14 mutation V138E leads to partly unfolded PKCγ associated with an exposed C-terminus, altered kinetics, phosphorylation and enhanced insolubilization.
Jezierska J; Goedhart J; Kampinga HH; Reits EA; Verbeek DS
J Neurochem; 2014 Mar; 128(5):741-51. PubMed ID: 24134140
[TBL] [Abstract][Full Text] [Related]
7. Calcium Signaling, PKC Gamma, IP3R1 and CAR8 Link Spinocerebellar Ataxias and Purkinje Cell Dendritic Development.
Shimobayashi E; Kapfhammer JP
Curr Neuropharmacol; 2018 Jan; 16(2):151-159. PubMed ID: 28554312
[TBL] [Abstract][Full Text] [Related]
8. Pharmacological induction of heat shock proteins ameliorates toxicity of mutant PKCγ in spinocerebellar ataxia type 14.
Nakazono A; Adachi N; Takahashi H; Seki T; Hamada D; Ueyama T; Sakai N; Saito N
J Biol Chem; 2018 Sep; 293(38):14758-14774. PubMed ID: 30093405
[TBL] [Abstract][Full Text] [Related]
9. PKC gamma mutations in spinocerebellar ataxia type 14 affect C1 domain accessibility and kinase activity leading to aberrant MAPK signaling.
Verbeek DS; Goedhart J; Bruinsma L; Sinke RJ; Reits EA
J Cell Sci; 2008 Jul; 121(Pt 14):2339-49. PubMed ID: 18577575
[TBL] [Abstract][Full Text] [Related]
10. Mutation in the catalytic domain of protein kinase C gamma and extension of the phenotype associated with spinocerebellar ataxia type 14.
Stevanin G; Hahn V; Lohmann E; Bouslam N; Gouttard M; Soumphonphakdy C; Welter ML; Ollagnon-Roman E; Lemainque A; Ruberg M; Brice A; Durr A
Arch Neurol; 2004 Aug; 61(8):1242-8. PubMed ID: 15313841
[TBL] [Abstract][Full Text] [Related]
11. Loss of Purkinje cells in the PKCgamma H101Y transgenic mouse.
Zhang Y; Snider A; Willard L; Takemoto DJ; Lin D
Biochem Biophys Res Commun; 2009 Jan; 378(3):524-8. PubMed ID: 19056342
[TBL] [Abstract][Full Text] [Related]
12. A novel H101Q mutation causes PKCgamma loss in spinocerebellar ataxia type 14.
Alonso I; Costa C; Gomes A; Ferro A; Seixas AI; Silva S; Cruz VT; Coutinho P; Sequeiros J; Silveira I
J Hum Genet; 2005; 50(10):523-529. PubMed ID: 16189624
[TBL] [Abstract][Full Text] [Related]
13. Mutant PKCγ in spinocerebellar ataxia type 14 disrupts synapse elimination and long-term depression in Purkinje cells in vivo.
Shuvaev AN; Horiuchi H; Seki T; Goenawan H; Irie T; Iizuka A; Sakai N; Hirai H
J Neurosci; 2011 Oct; 31(40):14324-34. PubMed ID: 21976518
[TBL] [Abstract][Full Text] [Related]
14. Mutations in protein kinase Cγ promote spinocerebellar ataxia type 14 by impairing kinase autoinhibition.
Pilo CA; Baffi TR; Kornev AP; Kunkel MT; Malfavon M; Chen DH; Rossitto LA; Chen DX; Huang LC; Longman C; Kannan N; Raskind WH; Gonzalez DJ; Taylor SS; Gorrie G; Newton AC
Sci Signal; 2022 Sep; 15(753):eabk1147. PubMed ID: 36166510
[TBL] [Abstract][Full Text] [Related]
15. Simplified Model of PKCγ Signaling Dysregulation and Cytosol-to-Membrane Translocation Kinetics During Neurodegenerative Spinocerebellar Ataxia Type 14 (SCA14).
Aslam N; Alvi F
Front Neurosci; 2019; 13():1397. PubMed ID: 32082104
[TBL] [Abstract][Full Text] [Related]
16. Enzymological analysis of mutant protein kinase Cgamma causing spinocerebellar ataxia type 14 and dysfunction in Ca2+ homeostasis.
Adachi N; Kobayashi T; Takahashi H; Kawasaki T; Shirai Y; Ueyama T; Matsuda T; Seki T; Sakai N; Saito N
J Biol Chem; 2008 Jul; 283(28):19854-63. PubMed ID: 18499672
[TBL] [Abstract][Full Text] [Related]
17. Comparison of two families with and without ataxia harboring novel variants in PRKCG.
Tada Y; Kume K; Noguchi S; Sekiya T; Nishinaka K; Ishiguchi H; Koh J; Emori S; Nakayama Y; Kurashige T; Izumi Y; Ito H; Sakai N; Kawakami H
J Hum Genet; 2022 Oct; 67(10):595-599. PubMed ID: 35760954
[TBL] [Abstract][Full Text] [Related]
18. Protein kinase C gamma mutations in spinocerebellar ataxia 14 increase kinase activity and alter membrane targeting.
Verbeek DS; Knight MA; Harmison GG; Fischbeck KH; Howell BW
Brain; 2005 Feb; 128(Pt 2):436-42. PubMed ID: 15618281
[TBL] [Abstract][Full Text] [Related]
19. Spinocerebellar ataxia type 14 caused by a mutation in protein kinase C gamma.
Yabe I; Sasaki H; Chen DH; Raskind WH; Bird TD; Yamashita I; Tsuji S; Kikuchi S; Tashiro K
Arch Neurol; 2003 Dec; 60(12):1749-51. PubMed ID: 14676051
[TBL] [Abstract][Full Text] [Related]
20. Episodic ataxia and severe infantile phenotype in spinocerebellar ataxia type 14: expansion of the phenotype and novel mutations.
De Michele G; Galatolo D; Galosi S; Mignarri A; Silvestri G; Casali C; Leuzzi V; Ricca I; Barghigiani M; Tessa A; Cioffi E; Caputi C; Riso V; Dotti MT; Saccà F; De Michele G; Cocozza S; Filla A; Santorelli FM
J Neurol; 2022 Mar; 269(3):1476-1484. PubMed ID: 34292398
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
