BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

384 related articles for article (PubMed ID: 30253188)

  • 1. Dual roles of different redox forms of complement factor H in protecting against age related macular degeneration.
    Krilis M; Qi M; Qi J; Wong JWH; Guymer R; Liew G; Hunyor AP; Madigan M; McCluskey P; Weaver J; Krilis SA; Giannakopoulos B
    Free Radic Biol Med; 2018 Dec; 129():237-246. PubMed ID: 30253188
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Age-related macular degeneration and the role of the complement system.
    McHarg S; Clark SJ; Day AJ; Bishop PN
    Mol Immunol; 2015 Sep; 67(1):43-50. PubMed ID: 25804937
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Heparan sulfate, including that in Bruch's membrane, inhibits the complement alternative pathway: implications for age-related macular degeneration.
    Kelly U; Yu L; Kumar P; Ding JD; Jiang H; Hageman GS; Arshavsky VY; Frank MM; Hauser MA; Rickman CB
    J Immunol; 2010 Nov; 185(9):5486-94. PubMed ID: 20876352
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Nitration of tyrosines in complement factor H domains alters its immunological activity and mediates a pathogenic role in age related macular degeneration.
    Krilis M; Qi M; Madigan MC; Wong JWH; Abdelatti M; Guymer RH; Whitelock J; McCluskey P; Zhang P; Qi J; Hunyor AP; Krilis SA; Giannakopoulos B
    Oncotarget; 2017 Jul; 8(30):49016-49032. PubMed ID: 28159936
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Bisretinoid-mediated complement activation on retinal pigment epithelial cells is dependent on complement factor H haplotype.
    Radu RA; Hu J; Jiang Z; Bok D
    J Biol Chem; 2014 Mar; 289(13):9113-20. PubMed ID: 24550392
    [TBL] [Abstract][Full Text] [Related]  

  • 6. C-reactive protein and complement factor H in aged human eyes and eyes with age-related macular degeneration.
    Bhutto IA; Baba T; Merges C; Juriasinghani V; McLeod DS; Lutty GA
    Br J Ophthalmol; 2011 Sep; 95(9):1323-30. PubMed ID: 21633121
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Identification of factor H-like protein 1 as the predominant complement regulator in Bruch's membrane: implications for age-related macular degeneration.
    Clark SJ; Schmidt CQ; White AM; Hakobyan S; Morgan BP; Bishop PN
    J Immunol; 2014 Nov; 193(10):4962-70. PubMed ID: 25305316
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Alterations in Extracellular Matrix/Bruch's Membrane Can Cause the Activation of the Alternative Complement Pathway via Tick-Over.
    Fernandez-Godino R
    Adv Exp Med Biol; 2018; 1074():29-35. PubMed ID: 29721924
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Impaired binding of the age-related macular degeneration-associated complement factor H 402H allotype to Bruch's membrane in human retina.
    Clark SJ; Perveen R; Hakobyan S; Morgan BP; Sim RB; Bishop PN; Day AJ
    J Biol Chem; 2010 Sep; 285(39):30192-202. PubMed ID: 20660596
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Plasma levels of complement proteins from the alternative pathway in patients with age-related macular degeneration are independent of Complement Factor H Tyr⁴⁰²His polymorphism.
    Silva AS; Teixeira AG; Bavia L; Lin F; Velletri R; Belfort R; Isaac L
    Mol Vis; 2012; 18():2288-99. PubMed ID: 22969267
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Risk alleles in CFH and ARMS2 are independently associated with systemic complement activation in age-related macular degeneration.
    Smailhodzic D; Klaver CC; Klevering BJ; Boon CJ; Groenewoud JM; Kirchhof B; Daha MR; den Hollander AI; Hoyng CB
    Ophthalmology; 2012 Feb; 119(2):339-46. PubMed ID: 22133792
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Human complement factor H Y402H polymorphism causes an age-related macular degeneration phenotype and lipoprotein dysregulation in mice.
    Landowski M; Kelly U; Klingeborn M; Groelle M; Ding JD; Grigsby D; Bowes Rickman C
    Proc Natl Acad Sci U S A; 2019 Feb; 116(9):3703-3711. PubMed ID: 30808757
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Plasma complement components and activation fragments: associations with age-related macular degeneration genotypes and phenotypes.
    Reynolds R; Hartnett ME; Atkinson JP; Giclas PC; Rosner B; Seddon JM
    Invest Ophthalmol Vis Sci; 2009 Dec; 50(12):5818-27. PubMed ID: 19661236
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis of complement factor H by retinal pigment epithelial cells is down-regulated by oxidized photoreceptor outer segments.
    Chen M; Forrester JV; Xu H
    Exp Eye Res; 2007 Apr; 84(4):635-45. PubMed ID: 17292886
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The effect of photo-oxidative stress and inflammatory cytokine on complement factor H expression in retinal pigment epithelial cells.
    Lau LI; Chiou SH; Liu CJ; Yen MY; Wei YH
    Invest Ophthalmol Vis Sci; 2011 Aug; 52(9):6832-41. PubMed ID: 21743006
    [TBL] [Abstract][Full Text] [Related]  

  • 16. CFH Haploinsufficiency and Complement Alterations in Early-Onset Macular Degeneration.
    Lim RR; Shirali S; Rowlan J; Engel AL; Nazario M; Gonzalez K; Tong A; Neitz J; Neitz M; Chao JR
    Invest Ophthalmol Vis Sci; 2024 Apr; 65(4):43. PubMed ID: 38683564
    [TBL] [Abstract][Full Text] [Related]  

  • 17. CFH Loss in Human RPE Cells Leads to Inflammation and Complement System Dysregulation via the NF-κB Pathway.
    Armento A; Schmidt TL; Sonntag I; Merle DA; Jarboui MA; Kilger E; Clark SJ; Ueffing M
    Int J Mol Sci; 2021 Aug; 22(16):. PubMed ID: 34445430
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Assessment of Proteins Associated With Complement Activation and Inflammation in Maculae of Human Donors Homozygous Risk at Chromosome 1 CFH-to-F13B.
    Keenan TD; Toso M; Pappas C; Nichols L; Bishop PN; Hageman GS
    Invest Ophthalmol Vis Sci; 2015 Jul; 56(8):4870-9. PubMed ID: 26218915
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Regulation of age-related macular degeneration-like pathology by complement factor H.
    Toomey CB; Kelly U; Saban DR; Bowes Rickman C
    Proc Natl Acad Sci U S A; 2015 Jun; 112(23):E3040-9. PubMed ID: 25991857
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Loss of Complement Factor H impairs antioxidant capacity and energy metabolism of human RPE cells.
    Armento A; Honisch S; Panagiotakopoulou V; Sonntag I; Jacob A; Bolz S; Kilger E; Deleidi M; Clark S; Ueffing M
    Sci Rep; 2020 Jun; 10(1):10320. PubMed ID: 32587311
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 20.