BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

189 related articles for article (PubMed ID: 30254074)

  • 1. Structures of human cytochrome P450 1A1 with bergamottin and erlotinib reveal active-site modifications for binding of diverse ligands.
    Bart AG; Scott EE
    J Biol Chem; 2018 Dec; 293(50):19201-19210. PubMed ID: 30254074
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Cytochrome P450 1A1 opens up to new substrates.
    Munro AW
    J Biol Chem; 2018 Dec; 293(50):19211-19212. PubMed ID: 30552114
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Human Cytochrome P450 1A1 Adapts Active Site for Atypical Nonplanar Substrate.
    Bart AG; Takahashi RH; Wang X; Scott EE
    Drug Metab Dispos; 2020 Feb; 48(2):86-92. PubMed ID: 31757797
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Human cytochrome P450 1A1 structure and utility in understanding drug and xenobiotic metabolism.
    Walsh AA; Szklarz GD; Scott EE
    J Biol Chem; 2013 May; 288(18):12932-43. PubMed ID: 23508959
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Molecular modeling of cytochrome P450 1A1: enzyme-substrate interactions and substrate binding affinities.
    Szklarz GD; Paulsen MD
    J Biomol Struct Dyn; 2002 Oct; 20(2):155-62. PubMed ID: 12354067
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The Grapefruit Effect: Interaction between Cytochrome P450 and Coumarin Food Components, Bergamottin, Fraxidin and Osthole. X-ray Crystal Structure and DFT Studies.
    Rossi M; Aktar S; Davis M; Hefter Feuss E; Roman-Holba S; Wen K; Gahn C; Caruso F
    Molecules; 2020 Jul; 25(14):. PubMed ID: 32664320
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Inhibition of human and rat CYP1A1 enzyme by grapefruit juice compounds.
    Santes-Palacios R; Romo-Mancillas A; Camacho-Carranza R; Espinosa-Aguirre JJ
    Toxicol Lett; 2016 Sep; 258():267-275. PubMed ID: 27444380
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Natural furocoumarins as inducers and inhibitors of cytochrome P450 1A1 in rat hepatocytes.
    Baumgart A; Schmidt M; Schmitz HJ; Schrenk D
    Biochem Pharmacol; 2005 Feb; 69(4):657-67. PubMed ID: 15670584
    [TBL] [Abstract][Full Text] [Related]  

  • 9. 7-Ethynylcoumarins: selective inhibitors of human cytochrome P450s 1A1 and 1A2.
    Liu J; Nguyen TT; Dupart PS; Sridhar J; Zhang X; Zhu N; Stevens CL; Foroozesh M
    Chem Res Toxicol; 2012 May; 25(5):1047-57. PubMed ID: 22443586
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Characterization of differences in substrate specificity among CYP1A1, CYP1A2 and CYP1B1: an integrated approach employing molecular docking and molecular dynamics simulations.
    Kesharwani SS; Nandekar PP; Pragyan P; Rathod V; Sangamwar AT
    J Mol Recognit; 2016 Aug; 29(8):370-90. PubMed ID: 26916064
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Exploring CYP1A1 as anticancer target: homology modeling and in silico inhibitor design.
    Sangamwar AT; Labhsetwar LB; Kuberkar SV
    J Mol Model; 2008 Nov; 14(11):1101-9. PubMed ID: 18665399
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Role of cytochrome P450 1a1 and 1b1 in the metabolic activation of 7,12-dimethylbenz[a]anthracene and the effects of naturally occurring furanocoumarins on skin tumor initiation.
    Kleiner HE; Vulimiri SV; Reed MJ; Uberecken A; DiGiovanni J
    Chem Res Toxicol; 2002 Feb; 15(2):226-35. PubMed ID: 11849049
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Theoretical investigation of differences in nitroreduction of aristolochic acid I by cytochromes P450 1A1, 1A2 and 1B1.
    Jerabek P; Martinek V; Stiborova M
    Neuro Endocrinol Lett; 2012; 33 Suppl 3():25-32. PubMed ID: 23353840
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Cytochrome P450 Binding and Bioactivation of Tumor-Targeted Duocarmycin Agents.
    Bart AG; Morais G; Vangala VR; Loadman PM; Pors K; Scott EE
    Drug Metab Dispos; 2022 Jan; 50(1):49-57. PubMed ID: 34607808
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Review of Ligand Specificity Factors for CYP1A Subfamily Enzymes from Molecular Modeling Studies Reported to-Date.
    Sridhar J; Goyal N; Liu J; Foroozesh M
    Molecules; 2017 Jul; 22(7):. PubMed ID: 28698457
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Activation of microsomal glutathione S-transferase and inhibition of cytochrome P450 1A1 activity as a model system for detecting protein alkylation by thiourea-containing compounds in rat liver microsomes.
    Onderwater RC; Commandeur JN; Menge WM; Vermeulen NP
    Chem Res Toxicol; 1999 May; 12(5):396-402. PubMed ID: 10328749
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Ortho-Methylarylamines as Time-Dependent Inhibitors of Cytochrome P450 1A1 Enzyme.
    Sridhar J; Liu J; Komati R; Schroeder R; Jiang Q; Tram P; Riley K; Foroozesh M
    Drug Metab Lett; 2017; 10(4):270-277. PubMed ID: 28000546
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Modulation of CYP1A1 metabolism: From adverse health effects to chemoprevention and therapeutic options.
    Mescher M; Haarmann-Stemmann T
    Pharmacol Ther; 2018 Jul; 187():71-87. PubMed ID: 29458109
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Comparative CYP1A1 and CYP1B1 substrate and inhibitor profile of dietary flavonoids.
    Androutsopoulos VP; Papakyriakou A; Vourloumis D; Spandidos DA
    Bioorg Med Chem; 2011 May; 19(9):2842-9. PubMed ID: 21482471
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Structural requirements for potent direct inhibition of human cytochrome P450 1A1 by cannabidiol: role of pentylresorcinol moiety.
    Yamaori S; Okushima Y; Masuda K; Kushihara M; Katsu T; Narimatsu S; Yamamoto I; Watanabe K
    Biol Pharm Bull; 2013; 36(7):1197-203. PubMed ID: 23811569
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.