289 related articles for article (PubMed ID: 30254335)
1. Small molecule inhibitors reveal allosteric regulation of USP14 via steric blockade.
Wang Y; Jiang Y; Ding S; Li J; Song N; Ren Y; Hong D; Wu C; Li B; Wang F; He W; Wang J; Mei Z
Cell Res; 2018 Dec; 28(12):1186-1194. PubMed ID: 30254335
[TBL] [Abstract][Full Text] [Related]
2. An inhibitor of the proteasomal deubiquitinating enzyme USP14 induces tau elimination in cultured neurons.
Boselli M; Lee BH; Robert J; Prado MA; Min SW; Cheng C; Silva MC; Seong C; Elsasser S; Hatle KM; Gahman TC; Gygi SP; Haggarty SJ; Gan L; King RW; Finley D
J Biol Chem; 2017 Nov; 292(47):19209-19225. PubMed ID: 28972160
[TBL] [Abstract][Full Text] [Related]
3. A small-molecule inhibitor of deubiquitinating enzyme USP14 inhibits Dengue virus replication.
Nag DK; Finley D
Virus Res; 2012 Apr; 165(1):103-6. PubMed ID: 22306365
[TBL] [Abstract][Full Text] [Related]
4. USP14 inhibitor attenuates cerebral ischemia/reperfusion-induced neuronal injury in mice.
Min JW; Lü L; Freeling JL; Martin DS; Wang H
J Neurochem; 2017 Mar; 140(5):826-833. PubMed ID: 28029679
[TBL] [Abstract][Full Text] [Related]
5. Neurotoxic mechanisms by which the USP14 inhibitor IU1 depletes ubiquitinated proteins and Tau in rat cerebral cortical neurons: Relevance to Alzheimer's disease.
Kiprowska MJ; Stepanova A; Todaro DR; Galkin A; Haas A; Wilson SM; Figueiredo-Pereira ME
Biochim Biophys Acta Mol Basis Dis; 2017 Jun; 1863(6):1157-1170. PubMed ID: 28372990
[TBL] [Abstract][Full Text] [Related]
6. USP14 inhibitor IU1 prevents ventilator-induced lung injury in rats.
Xu YH; Guo NL
Cell Mol Biol (Noisy-le-grand); 2014 Sep; 60(2):50-4. PubMed ID: 25198582
[TBL] [Abstract][Full Text] [Related]
7. Small-Molecule Inhibitors Targeting Proteasome-Associated Deubiquitinases.
Moon S; Muniyappan S; Lee SB; Lee BH
Int J Mol Sci; 2021 Jun; 22(12):. PubMed ID: 34207520
[TBL] [Abstract][Full Text] [Related]
8. Ubiquitinated proteins promote the association of proteasomes with the deubiquitinating enzyme Usp14 and the ubiquitin ligase Ube3c.
Kuo CL; Goldberg AL
Proc Natl Acad Sci U S A; 2017 Apr; 114(17):E3404-E3413. PubMed ID: 28396413
[TBL] [Abstract][Full Text] [Related]
9. Discovery of new promising USP14 inhibitors: computational evaluation of the thumb-palm pocket.
Adelakun N; Obaseki I; Adeniyi A; Fapohunda O; Obaseki E; Omotuyi O
J Biomol Struct Dyn; 2022 Apr; 40(7):3060-3070. PubMed ID: 33170088
[TBL] [Abstract][Full Text] [Related]
10. Structurally-defined deubiquitinase inhibitors provide opportunities to investigate disease mechanisms.
Wertz IE; Murray JM
Drug Discov Today Technol; 2019 Apr; 31():109-123. PubMed ID: 31200854
[TBL] [Abstract][Full Text] [Related]
11. USP14 Inhibition Regulates Tumorigenesis by Inducing Autophagy in Lung Cancer In Vitro.
Han KH; Kwak M; Lee TH; Park MS; Jeong IH; Kim MJ; Jin JO; Lee PC
Int J Mol Sci; 2019 Oct; 20(21):. PubMed ID: 31653087
[TBL] [Abstract][Full Text] [Related]
12. A ubiquitinome analysis to study the functional roles of the proteasome associated deubiquitinating enzymes USP14 and UCH37.
van der Wal L; Bezstarosti K; Demmers JAA
J Proteomics; 2022 Jun; 262():104592. PubMed ID: 35489684
[TBL] [Abstract][Full Text] [Related]
13. Generation and Validation of Intracellular Ubiquitin Variant Inhibitors for USP7 and USP10.
Zhang W; Sartori MA; Makhnevych T; Federowicz KE; Dong X; Liu L; Nim S; Dong A; Yang J; Li Y; Haddad D; Ernst A; Heerding D; Tong Y; Moffat J; Sidhu SS
J Mol Biol; 2017 Nov; 429(22):3546-3560. PubMed ID: 28587923
[TBL] [Abstract][Full Text] [Related]
14. Ubiquitin-specific protease 14 regulates c-Jun N-terminal kinase signaling at the neuromuscular junction.
Vaden JH; Bhattacharyya BJ; Chen PC; Watson JA; Marshall AG; Phillips SE; Wilson JA; King GD; Miller RJ; Wilson SM
Mol Neurodegener; 2015 Jan; 10():3. PubMed ID: 25575639
[TBL] [Abstract][Full Text] [Related]
15. USP14 Regulates Cancer Cell Growth in a Fatty Acid Synthase-Independent Manner.
Yang JS; Yoon N; Kong M; Jung BH; Lee H; Park J
Int J Mol Sci; 2021 Dec; 22(24):. PubMed ID: 34948233
[TBL] [Abstract][Full Text] [Related]
16. Structure and mechanisms of the proteasome-associated deubiquitinating enzyme USP14.
Hu M; Li P; Song L; Jeffrey PD; Chenova TA; Wilkinson KD; Cohen RE; Shi Y
EMBO J; 2005 Nov; 24(21):3747-56. PubMed ID: 16211010
[TBL] [Abstract][Full Text] [Related]
17. USP14: Structure, Function, and Target Inhibition.
Wang F; Ning S; Yu B; Wang Y
Front Pharmacol; 2021; 12():801328. PubMed ID: 35069211
[TBL] [Abstract][Full Text] [Related]
18. Molecular Understanding of USP7 Substrate Recognition and C-Terminal Activation.
Rougé L; Bainbridge TW; Kwok M; Tong R; Di Lello P; Wertz IE; Maurer T; Ernst JA; Murray J
Structure; 2016 Aug; 24(8):1335-1345. PubMed ID: 27452404
[TBL] [Abstract][Full Text] [Related]
19. Structure-Guided Development of a Potent and Selective Non-covalent Active-Site Inhibitor of USP7.
Lamberto I; Liu X; Seo HS; Schauer NJ; Iacob RE; Hu W; Das D; Mikhailova T; Weisberg EL; Engen JR; Anderson KC; Chauhan D; Dhe-Paganon S; Buhrlage SJ
Cell Chem Biol; 2017 Dec; 24(12):1490-1500.e11. PubMed ID: 29056421
[TBL] [Abstract][Full Text] [Related]
20. Emerging role of ubiquitin-specific protease 14 in oncogenesis and development of tumor: Therapeutic implication.
Liu B; Chen J; Zhang S
Life Sci; 2019 Dec; 239():116875. PubMed ID: 31676235
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
