BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

139 related articles for article (PubMed ID: 30267747)

  • 1. Mechanistic and Structural Origins of the Asymmetric Barrier to Prion-like Cross-Seeding between Tau-3R and Tau-4R.
    Kumar H; Udgaonkar JB
    J Mol Biol; 2018 Dec; 430(24):5304-5312. PubMed ID: 30267747
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Structural disorder in four-repeat Tau fibrils reveals a new mechanism for barriers to cross-seeding of Tau isoforms.
    Weismiller HA; Murphy R; Wei G; Ma B; Nussinov R; Margittai M
    J Biol Chem; 2018 Nov; 293(45):17336-17348. PubMed ID: 30242125
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The Lys 280 → Gln mutation mimicking disease-linked acetylation of Lys 280 in tau extends the structural core of fibrils and modulates their catalytic properties.
    Kumar H; Udgaonkar JB
    Protein Sci; 2021 Apr; 30(4):785-803. PubMed ID: 33496017
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Three- and four-repeat Tau coassemble into heterogeneous filaments: an implication for Alzheimer disease.
    Siddiqua A; Margittai M
    J Biol Chem; 2010 Nov; 285(48):37920-6. PubMed ID: 20921227
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Tau protein assembles into isoform- and disulfide-dependent polymorphic fibrils with distinct structural properties.
    Furukawa Y; Kaneko K; Nukina N
    J Biol Chem; 2011 Aug; 286(31):27236-46. PubMed ID: 21659525
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Variations in filament conformation dictate seeding barrier between three- and four-repeat tau.
    Dinkel PD; Siddiqua A; Huynh H; Shah M; Margittai M
    Biochemistry; 2011 May; 50(20):4330-6. PubMed ID: 21510682
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Cross-seeding and conformational selection between three- and four-repeat human Tau proteins.
    Yu X; Luo Y; Dinkel P; Zheng J; Wei G; Margittai M; Nussinov R; Ma B
    J Biol Chem; 2012 Apr; 287(18):14950-9. PubMed ID: 22393063
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Precision proteoform design for 4R tau isoform selective templated aggregation.
    Longhini AP; DuBose A; Lobo S; Vijayan V; Bai Y; Rivera EK; Sala-Jarque J; Nikitina A; Carrettiero DC; Unger MT; Sclafani OR; Fu V; Beckett ER; Vigers M; Buée L; Landrieu I; Shell S; Shea JE; Han S; Kosik KS
    Proc Natl Acad Sci U S A; 2024 Apr; 121(15):e2320456121. PubMed ID: 38568974
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Three repeat isoforms of tau inhibit assembly of four repeat tau filaments.
    Adams SJ; DeTure MA; McBride M; Dickson DW; Petrucelli L
    PLoS One; 2010 May; 5(5):e10810. PubMed ID: 20520830
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Elongation of Fibrils Formed by a Tau Fragment is Inhibited by a Transient Dimeric Intermediate.
    Kumar H; Udgaonkar JB
    J Phys Chem B; 2022 May; 126(18):3385-3397. PubMed ID: 35503811
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Comparison of size distribution and (Pro249-Ser258) epitope exposure in in vitro and in vivo derived Tau fibrils.
    Marreiro A; Van Kolen K; Sousa C; Temmerman L; Vasconcelos B; Crespo-Rodriguez R; van Weering JRT; Van Dam D; De Deyn PP; Apetri A; Schoofs L; Mercken MH
    BMC Mol Cell Biol; 2020 Nov; 21(1):81. PubMed ID: 33183222
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Transmission of tauopathy strains is independent of their isoform composition.
    He Z; McBride JD; Xu H; Changolkar L; Kim SJ; Zhang B; Narasimhan S; Gibbons GS; Guo JL; Kozak M; Schellenberg GD; Trojanowski JQ; Lee VM
    Nat Commun; 2020 Jan; 11(1):7. PubMed ID: 31911587
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Amyloidogenic cross-seeding of Tau protein: Transient emergence of structural variants of fibrils.
    Nizynski B; Nieznanska H; Dec R; Boyko S; Dzwolak W; Nieznanski K
    PLoS One; 2018; 13(7):e0201182. PubMed ID: 30024984
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Time- and dose-dependent seeding tendency of exogenous tau R2 and R3 aggregates in cells.
    Annadurai N; Hrubý J; Kubíčková A; Malina L; Hajdúch M; Das V
    Biochem Biophys Res Commun; 2023 Apr; 653():102-105. PubMed ID: 36863211
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A thiol-based intramolecular redox switch in four-repeat tau controls fibril assembly and disassembly.
    Weismiller HA; Holub TJ; Krzesinski BJ; Margittai M
    J Biol Chem; 2021 Sep; 297(3):101021. PubMed ID: 34339733
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Conformational basis for asymmetric seeding barrier in filaments of three- and four-repeat tau.
    Siddiqua A; Luo Y; Meyer V; Swanson MA; Yu X; Wei G; Zheng J; Eaton GR; Ma B; Nussinov R; Eaton SS; Margittai M
    J Am Chem Soc; 2012 Jun; 134(24):10271-8. PubMed ID: 22656332
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Propagation of Tau aggregates.
    Goedert M; Spillantini MG
    Mol Brain; 2017 May; 10(1):18. PubMed ID: 28558799
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Differential interaction and aggregation of 3-repeat and 4-repeat tau isoforms with 14-3-3zeta protein.
    Sadik G; Tanaka T; Kato K; Yanagi K; Kudo T; Takeda M
    Biochem Biophys Res Commun; 2009 May; 383(1):37-41. PubMed ID: 19324008
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Glycation alter the process of Tau phosphorylation to change Tau isoforms aggregation property.
    Liu K; Liu Y; Li L; Qin P; Iqbal J; Deng Y; Qing H
    Biochim Biophys Acta; 2016 Feb; 1862(2):192-201. PubMed ID: 26655600
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Tau mutation S356T in the three repeat isoform leads to microtubule dysfunction and promotes prion-like seeded aggregation.
    Xia Y; Bell BM; Kim JD; Giasson BI
    Front Neurosci; 2023; 17():1181804. PubMed ID: 37304025
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.