These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

153 related articles for article (PubMed ID: 30267816)

  • 1. A polysaccharide from Antrodia cinnamomea mycelia exerts antitumor activity through blocking of TOP1/TDP1-mediated DNA repair pathway.
    Zhang Y; Wang Z; Li D; Zang W; Zhu H; Wu P; Mei Y; Liang Y
    Int J Biol Macromol; 2018 Dec; 120(Pt B):1551-1560. PubMed ID: 30267816
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Alpha-terpineol affects synthesis and antitumor activity of triterpenoids from Antrodia cinnamomea mycelia in solid-state culture.
    Zhang Y; Li D; Wang Z; Zang W; Rao P; Liang Y; Mei Y
    Food Funct; 2018 Dec; 9(12):6517-6525. PubMed ID: 30474680
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A novel polysaccharide from mycelia of cultured Phellinus linteus displays antitumor activity through apoptosis.
    Mei Y; Zhu H; Hu Q; Liu Y; Zhao S; Peng N; Liang Y
    Carbohydr Polym; 2015 Jun; 124():90-7. PubMed ID: 25839798
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Tyrosyl-DNA phosphodiesterase 2 (TDP2) repairs topoisomerase 1 DNA-protein crosslinks and 3'-blocking lesions in the absence of tyrosyl-DNA phosphodiesterase 1 (TDP1).
    Tsuda M; Kitamasu K; Kumagai C; Sugiyama K; Nakano T; Ide H
    DNA Repair (Amst); 2020; 91-92():102849. PubMed ID: 32460231
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis of Methoxy-, Methylenedioxy-, Hydroxy-, and Halo-Substituted Benzophenanthridinone Derivatives as DNA Topoisomerase IB (TOP1) and Tyrosyl-DNA Phosphodiesterase 1 (TDP1) Inhibitors and Their Biological Activity for Drug-Resistant Cancer.
    Hu DX; Tang WL; Zhang Y; Yang H; Wang W; Agama K; Pommier Y; An LK
    J Med Chem; 2021 Jun; 64(11):7617-7629. PubMed ID: 34008967
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Discovery, Synthesis, and Evaluation of Oxynitidine Derivatives as Dual Inhibitors of DNA Topoisomerase IB (TOP1) and Tyrosyl-DNA Phosphodiesterase 1 (TDP1), and Potential Antitumor Agents.
    Zhang XR; Wang HW; Tang WL; Zhang Y; Yang H; Hu DX; Ravji A; Marchand C; Kiselev E; Ofori-Atta K; Agama K; Pommier Y; An LK
    J Med Chem; 2018 Nov; 61(22):9908-9930. PubMed ID: 30336023
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Natural Products and Their Derivatives as Inhibitors of the DNA Repair Enzyme Tyrosyl-DNA Phosphodiesterase 1.
    Zakharenko AL; Luzina OA; Chepanova AA; Dyrkheeva NS; Salakhutdinov NF; Lavrik OI
    Int J Mol Sci; 2023 Mar; 24(6):. PubMed ID: 36982848
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Molecular mechanism of Antrodia cinnamomea sulfated polysaccharide on the suppression of lung cancer cell growth and migration via induction of transforming growth factor β receptor degradation.
    Lu MK; Lin TY; Chao CH; Hu CH; Hsu HY
    Int J Biol Macromol; 2017 Feb; 95():1144-1152. PubMed ID: 27818294
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Correlation between topoisomerase I and tyrosyl-DNA phosphodiesterase 1 activities in non-small cell lung cancer tissue.
    Jakobsen AK; Lauridsen KL; Samuel EB; Proszek J; Knudsen BR; Hager H; Stougaard M
    Exp Mol Pathol; 2015 Aug; 99(1):56-64. PubMed ID: 25987486
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Tyrosyl-DNA phosphodiesterase 1 targeting for modulation of camptothecin-based treatment.
    Beretta GL; Cossa G; Gatti L; Zunino F; Perego P
    Curr Med Chem; 2010; 17(15):1500-8. PubMed ID: 20166932
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Yeast Tdp1 and Rad1-Rad10 function as redundant pathways for repairing Top1 replicative damage.
    Vance JR; Wilson TE
    Proc Natl Acad Sci U S A; 2002 Oct; 99(21):13669-74. PubMed ID: 12368472
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Studying TDP1 Function in DNA Repair.
    Chiang SC; Liversidge K; El-Khamisy SF
    Methods Mol Biol; 2018; 1703():173-181. PubMed ID: 29177742
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Comparison of the apoptotic effects of supercritical fluid extracts of Antrodia cinnamomea mycelia on hepatocellular carcinoma cells.
    Lien HM; Chiu CH; Chen CC; Chang WL; Chyau CC; Peng RY
    Molecules; 2014 Jun; 19(7):9033-50. PubMed ID: 24979405
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Tyrosyl-DNA phosphodiesterase (Tdp1) participates in the repair of Top2-mediated DNA damage.
    Nitiss KC; Malik M; He X; White SW; Nitiss JL
    Proc Natl Acad Sci U S A; 2006 Jun; 103(24):8953-8. PubMed ID: 16751265
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Dual DNA topoisomerase 1 and tyrosyl-DNA phosphodiesterase 1 inhibition for improved anticancer activity.
    Zakharenko A; Dyrkheeva N; Lavrik O
    Med Res Rev; 2019 Jul; 39(4):1427-1441. PubMed ID: 31004352
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Tyrosyl-DNA phosphodiesterase as a target for anticancer therapy.
    Dexheimer TS; Antony S; Marchand C; Pommier Y
    Anticancer Agents Med Chem; 2008 May; 8(4):381-9. PubMed ID: 18473723
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Association of XRCC1 and tyrosyl DNA phosphodiesterase (Tdp1) for the repair of topoisomerase I-mediated DNA lesions.
    Plo I; Liao ZY; Barceló JM; Kohlhagen G; Caldecott KW; Weinfeld M; Pommier Y
    DNA Repair (Amst); 2003 Oct; 2(10):1087-100. PubMed ID: 13679147
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthesis of 11-aminoalkoxy substituted benzophenanthridine derivatives as tyrosyl-DNA phosphodiesterase 1 inhibitors and their anticancer activity.
    Yang H; Wang FT; Wu M; Wang W; Agama K; Pommier Y; An LK
    Bioorg Chem; 2022 Jun; 123():105789. PubMed ID: 35429714
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Epigenetic and genetic inactivation of tyrosyl-DNA-phosphodiesterase 1 (TDP1) in human lung cancer cells from the NCI-60 panel.
    Gao R; Das BB; Chatterjee R; Abaan OD; Agama K; Matuo R; Vinson C; Meltzer PS; Pommier Y
    DNA Repair (Amst); 2014 Jan; 13():1-9. PubMed ID: 24355542
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A Dual-Sensor-Based Screening System for In Vitro Selection of TDP1 Inhibitors.
    Jakobsen AK; Keller JG; Gonzalez M; Martin-Encinas E; Palacios F; Alonso C; Knudsen BR; Stougaard M
    Sensors (Basel); 2021 Jul; 21(14):. PubMed ID: 34300575
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.