BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

266 related articles for article (PubMed ID: 30268477)

  • 1. Elongation factor-2 kinase (eEF-2K) expression is associated with poor patient survival and promotes proliferation, invasion and tumor growth of lung cancer.
    Bircan HA; Gurbuz N; Pataer A; Caner A; Kahraman N; Bayraktar E; Bayraktar R; Erdogan MA; Kabil N; Ozpolat B
    Lung Cancer; 2018 Oct; 124():31-39. PubMed ID: 30268477
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Thymoquinone inhibits cell proliferation, migration, and invasion by regulating the elongation factor 2 kinase (eEF-2K) signaling axis in triple-negative breast cancer.
    Kabil N; Bayraktar R; Kahraman N; Mokhlis HA; Calin GA; Lopez-Berestein G; Ozpolat B
    Breast Cancer Res Treat; 2018 Oct; 171(3):593-605. PubMed ID: 29971628
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Elongation factor-2 kinase regulates TG2/β1 integrin/Src/uPAR pathway and epithelial-mesenchymal transition mediating pancreatic cancer cells invasion.
    Ashour AA; Gurbuz N; Alpay SN; Abdel-Aziz AA; Mansour AM; Huo L; Ozpolat B
    J Cell Mol Med; 2014 Nov; 18(11):2235-51. PubMed ID: 25215932
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Targeted silencing of elongation factor 2 kinase suppresses growth and sensitizes tumors to doxorubicin in an orthotopic model of breast cancer.
    Tekedereli I; Alpay SN; Tavares CD; Cobanoglu ZE; Kaoud TS; Sahin I; Sood AK; Lopez-Berestein G; Dalby KN; Ozpolat B
    PLoS One; 2012; 7(7):e41171. PubMed ID: 22911754
    [TBL] [Abstract][Full Text] [Related]  

  • 5. FOXM1 regulates expression of eukaryotic elongation factor 2 kinase and promotes proliferation, invasion and tumorgenesis of human triple negative breast cancer cells.
    Hamurcu Z; Ashour A; Kahraman N; Ozpolat B
    Oncotarget; 2016 Mar; 7(13):16619-35. PubMed ID: 26918606
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Modified gold-based siRNA nanotherapeutics for targeted therapy of triple-negative breast cancer.
    Shahbazi R; Asik E; Kahraman N; Turk M; Ozpolat B; Ulubayram K
    Nanomedicine (Lond); 2017 Aug; 12(16):1961-1973. PubMed ID: 28745127
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Targeting eukaryotic elongation factor-2 kinase suppresses the growth and peritoneal metastasis of ovarian cancer.
    Erdogan MA; Ashour A; Yuca E; Gorgulu K; Ozpolat B
    Cell Signal; 2021 May; 81():109938. PubMed ID: 33539938
    [TBL] [Abstract][Full Text] [Related]  

  • 8. What is the impact of eukaryotic elongation factor 2 kinase on cancer: A systematic review.
    Li S; Li Y; Bai Y
    Eur J Pharmacol; 2019 Aug; 857():172470. PubMed ID: 31226250
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Combined treatment of mitoxantrone sensitizes breast cancer cells to rapalogs through blocking eEF-2K-mediated activation of Akt and autophagy.
    Guan Y; Jiang S; Ye W; Ren X; Wang X; Zhang Y; Yin M; Wang K; Tao Y; Yang J; Cao D; Cheng Y
    Cell Death Dis; 2020 Nov; 11(11):948. PubMed ID: 33144562
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Inhibition of eEF-2 kinase sensitizes human nasopharyngeal carcinoma cells to lapatinib-induced apoptosis through the Src and Erk pathways.
    Liu L; Huang P; Wang Z; Chen N; Tang C; Lin Z; Peng P
    BMC Cancer; 2016 Oct; 16(1):813. PubMed ID: 27756261
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Targeting elongation factor-2 kinase (eEF-2K) induces apoptosis in human pancreatic cancer cells.
    Ashour AA; Abdel-Aziz AA; Mansour AM; Alpay SN; Huo L; Ozpolat B
    Apoptosis; 2014 Jan; 19(1):241-58. PubMed ID: 24193916
    [TBL] [Abstract][Full Text] [Related]  

  • 12. miRNA-193b-5p Suppresses Pancreatic Cancer Cell Proliferation, Invasion, Epithelial Mesenchymal Transition, and Tumor Growth by Inhibiting eEF2K.
    Gurbuz N; Kahraman N; Sonmez HE; Mokhlis HA; Kosar PA; Ozpolat B
    Anticancer Agents Med Chem; 2022; 22(14):2607-2618. PubMed ID: 35718922
    [TBL] [Abstract][Full Text] [Related]  

  • 13. eEF-2 kinase is a critical regulator of Warburg effect through controlling PP2A-A synthesis.
    Cheng Y; Ren X; Yuan Y; Shan Y; Li L; Chen X; Zhang L; Takahashi Y; Yang JW; Han B; Liao J; Li Y; Harvey H; Ryazanov A; Robertson GP; Wan G; Liu D; Chen AF; Tao Y; Yang JM
    Oncogene; 2016 Dec; 35(49):6293-6308. PubMed ID: 27181208
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Small interference RNA targeting tissue factor inhibits human lung adenocarcinoma growth in vitro and in vivo.
    Xu C; Gui Q; Chen W; Wu L; Sun W; Zhang N; Xu Q; Wang J; Fu X
    J Exp Clin Cancer Res; 2011 May; 30(1):63. PubMed ID: 21619686
    [TBL] [Abstract][Full Text] [Related]  

  • 15. eEF-2K knockdown synergizes with STS treatment to inhibit cell proliferation, migration, and invasion via the TG2/ERK pathway in A549 cells.
    Wang B; Gu X; Xiang BL; Zhao JQ; Zhang CH; Huang PD; Zhang ZH
    J Biochem Mol Toxicol; 2022 Oct; 36(10):e23158. PubMed ID: 35844142
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Death-associated protein kinase 3 controls the tumor progression of A549 cells through ERK MAPK/c-Myc signaling.
    Kake S; Usui T; Ohama T; Yamawaki H; Sato K
    Oncol Rep; 2017 Feb; 37(2):1100-1106. PubMed ID: 28075459
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Downregulation of NMI promotes tumor growth and predicts poor prognosis in human lung adenocarcinomas.
    Wang J; Zou K; Feng X; Chen M; Li C; Tang R; Xuan Y; Luo M; Chen W; Qiu H; Qin G; Li Y; Zhang C; Xiao B; Kang L; Kang T; Huang W; Yu X; Wu X; Deng W
    Mol Cancer; 2017 Oct; 16(1):158. PubMed ID: 29025423
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Effects of TGF-β signaling blockade on human A549 lung adenocarcinoma cell lines.
    Xu CC; Wu LM; Sun W; Zhang N; Chen WS; Fu XN
    Mol Med Rep; 2011; 4(5):1007-15. PubMed ID: 21725601
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Structure of the complex between calmodulin and a functional construct of eukaryotic elongation factor 2 kinase bound to an ATP-competitive inhibitor.
    Piserchio A; Isiorho EA; Dalby KN; Ghose R
    J Biol Chem; 2023 Jun; 299(6):104813. PubMed ID: 37172726
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Purification and characterization of tagless recombinant human elongation factor 2 kinase (eEF-2K) expressed in Escherichia coli.
    Abramczyk O; Tavares CD; Devkota AK; Ryazanov AG; Turk BE; Riggs AF; Ozpolat B; Dalby KN
    Protein Expr Purif; 2011 Oct; 79(2):237-44. PubMed ID: 21605678
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.