175 related articles for article (PubMed ID: 30270266)
1. [Development of an In Vitro System for Evaluating Intestinal Drug Disposition Using Human Induced Pluripotent Stem Cell-Derived Intestinal Epithelial Cells].
Iwao T
Yakugaku Zasshi; 2018; 138(10):1241-1247. PubMed ID: 30270266
[TBL] [Abstract][Full Text] [Related]
2. Inhibition of mitogen-activated protein kinase kinase, DNA methyltransferase, and transforming growth factor-β promotes differentiation of human induced pluripotent stem cells into enterocytes.
Kodama N; Iwao T; Kabeya T; Horikawa T; Niwa T; Kondo Y; Nakamura K; Matsunaga T
Drug Metab Pharmacokinet; 2016 Jun; 31(3):193-200. PubMed ID: 27161454
[TBL] [Abstract][Full Text] [Related]
3. Cyclic AMP Signaling Promotes the Differentiation of Human Induced Pluripotent Stem Cells into Intestinal Epithelial Cells.
Kabeya T; Qiu S; Hibino M; Nagasaki M; Kodama N; Iwao T; Matsunaga T
Drug Metab Dispos; 2018 Oct; 46(10):1411-1419. PubMed ID: 30068521
[TBL] [Abstract][Full Text] [Related]
4. Generation of enterocyte-like cells with pharmacokinetic functions from human induced pluripotent stem cells using small-molecule compounds.
Iwao T; Kodama N; Kondo Y; Kabeya T; Nakamura K; Horikawa T; Niwa T; Kurose K; Matsunaga T
Drug Metab Dispos; 2015 Apr; 43(4):603-10. PubMed ID: 25650381
[TBL] [Abstract][Full Text] [Related]
5. [Utilization of Human iPS Cells for Evaluation of Drug Disposition and Mucosal Damages in the Small Intestine].
Iwao T
Yakugaku Zasshi; 2023; 143(3):243-247. PubMed ID: 36858557
[TBL] [Abstract][Full Text] [Related]
6. Drug metabolizing enzyme and transporter protein profiles of hepatocytes derived from human embryonic and induced pluripotent stem cells.
Ulvestad M; Nordell P; Asplund A; Rehnström M; Jacobsson S; Holmgren G; Davidson L; Brolén G; Edsbagge J; Björquist P; Küppers-Munther B; Andersson TB
Biochem Pharmacol; 2013 Sep; 86(5):691-702. PubMed ID: 23856292
[TBL] [Abstract][Full Text] [Related]
7. 3D-fibroblast tissues constructed by a cell-coat technology enhance tight-junction formation of human colon epithelial cells.
Matsusaki M; Hikimoto D; Nishiguchi A; Kadowaki K; Ohura K; Imai T; Akashi M
Biochem Biophys Res Commun; 2015 Feb; 457(3):363-9. PubMed ID: 25576862
[TBL] [Abstract][Full Text] [Related]
8. Regional Expression Levels of Drug Transporters and Metabolizing Enzymes along the Pig and Human Intestinal Tract and Comparison with Caco-2 Cells.
Vaessen SF; van Lipzig MM; Pieters RH; Krul CA; Wortelboer HM; van de Steeg E
Drug Metab Dispos; 2017 Apr; 45(4):353-360. PubMed ID: 28153842
[TBL] [Abstract][Full Text] [Related]
9. Generation of Human iPSC-Derived Intestinal Epithelial Cell Monolayers by CDX2 Transduction.
Takayama K; Negoro R; Yamashita T; Kawai K; Ichikawa M; Mori T; Nakatsu N; Harada K; Ito S; Yamada H; Yamaura Y; Hirata K; Ishida S; Mizuguchi H
Cell Mol Gastroenterol Hepatol; 2019; 8(3):513-526. PubMed ID: 31228606
[TBL] [Abstract][Full Text] [Related]
10. In vitro investigations into the roles of drug transporters and metabolizing enzymes in the disposition and drug interactions of dolutegravir, a HIV integrase inhibitor.
Reese MJ; Savina PM; Generaux GT; Tracey H; Humphreys JE; Kanaoka E; Webster LO; Harmon KA; Clarke JD; Polli JW
Drug Metab Dispos; 2013 Feb; 41(2):353-61. PubMed ID: 23132334
[TBL] [Abstract][Full Text] [Related]
11. Pharmacokinetic functions of human induced pluripotent stem cell-derived small intestinal epithelial cells.
Kabeya T; Mima S; Imakura Y; Miyashita T; Ogura I; Yamada T; Yasujima T; Yuasa H; Iwao T; Matsunaga T
Drug Metab Pharmacokinet; 2020 Aug; 35(4):374-382. PubMed ID: 32651148
[TBL] [Abstract][Full Text] [Related]
12. Usefulness of Human Jejunal Spheroid-Derived Differentiated Intestinal Epithelial Cells for the Prediction of Intestinal Drug Absorption in Humans.
Michiba K; Maeda K; Shimomura O; Miyazaki Y; Hashimoto S; Oda T; Kusuhara H
Drug Metab Dispos; 2022 Mar; 50(3):204-213. PubMed ID: 34992074
[TBL] [Abstract][Full Text] [Related]
13. Generation of Intestinal Organoids Suitable for Pharmacokinetic Studies from Human Induced Pluripotent Stem Cells.
Onozato D; Yamashita M; Nakanishi A; Akagawa T; Kida Y; Ogawa I; Hashita T; Iwao T; Matsunaga T
Drug Metab Dispos; 2018 Nov; 46(11):1572-1580. PubMed ID: 29615438
[TBL] [Abstract][Full Text] [Related]
14. Characteristic Analysis of Intestinal Transport in Enterocyte-Like Cells Differentiated from Human Induced Pluripotent Stem Cells.
Kodama N; Iwao T; Katano T; Ohta K; Yuasa H; Matsunaga T
Drug Metab Dispos; 2016 Oct; 44(10):0. PubMed ID: 27417181
[TBL] [Abstract][Full Text] [Related]
15. Human small intestinal epithelial cells differentiated from adult intestinal stem cells as a novel system for predicting oral drug absorption in humans.
Takenaka T; Harada N; Kuze J; Chiba M; Iwao T; Matsunaga T
Drug Metab Dispos; 2014 Nov; 42(11):1947-54. PubMed ID: 25200868
[TBL] [Abstract][Full Text] [Related]
16. Application of Intestinal Epithelial Cells Differentiated from Human Induced Pluripotent Stem Cells for Studies of Prodrug Hydrolysis and Drug Absorption in the Small Intestine.
Akazawa T; Yoshida S; Ohnishi S; Kanazu T; Kawai M; Takahashi K
Drug Metab Dispos; 2018 Nov; 46(11):1497-1506. PubMed ID: 30135242
[TBL] [Abstract][Full Text] [Related]
17. Functional Comparison of Human Colonic Carcinoma Cell Lines and Primary Small Intestinal Epithelial Cells for Investigations of Intestinal Drug Permeability and First-Pass Metabolism.
Yamaura Y; Chapron BD; Wang Z; Himmelfarb J; Thummel KE
Drug Metab Dispos; 2016 Mar; 44(3):329-35. PubMed ID: 26700954
[TBL] [Abstract][Full Text] [Related]
18. Quantitative Atlas of Cytochrome P450, UDP-Glucuronosyltransferase, and Transporter Proteins in Jejunum of Morbidly Obese Subjects.
Miyauchi E; Tachikawa M; Declèves X; Uchida Y; Bouillot JL; Poitou C; Oppert JM; Mouly S; Bergmann JF; Terasaki T; Scherrmann JM; Lloret-Linares C
Mol Pharm; 2016 Aug; 13(8):2631-40. PubMed ID: 27347605
[TBL] [Abstract][Full Text] [Related]
19. Polycyclic aromatic hydrocarbons in food--efflux of the conjugated biomarker 1-hydroxypyrene is mediated by Breast Cancer Resistance Protein (ABCG2) in human intestinal Caco-2 cells.
Hessel S; Lampen A; Seidel A
Food Chem Toxicol; 2013 Dec; 62():797-804. PubMed ID: 24140465
[TBL] [Abstract][Full Text] [Related]
20. Simultaneous Evaluation of Membrane Permeability and UDP-Glucuronosyltransferase-Mediated Metabolism of Food-Derived Compounds Using Human Induced Pluripotent Stem Cell-Derived Small Intestinal Epithelial Cells.
Kitaguchi T; Mizota T; Ito M; Ohno K; Kobayashi K; Ogawa I; Qiu S; Iwao T; Hanioka N; Tanaka M; Matsunaga T
Drug Metab Dispos; 2022 Jan; 50(1):17-23. PubMed ID: 34670778
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]